Search Results - "Mengyun, Li"
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Delivery of mRNA vaccine with a lipid-like material potentiates antitumor efficacy through Toll-like receptor 4 signaling
Published in Proceedings of the National Academy of Sciences - PNAS (09-02-2021)“…Intracellular delivery of messenger RNA (mRNA)-based cancer vaccine has shown great potential to elicit antitumor immunity. To achieve robust antitumor…”
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Sensing of autoinducer-2 by functionally distinct receptors in prokaryotes
Published in Nature communications (23-10-2020)“…Autoinducer-2 (AI-2) is a quorum sensing signal that mediates communication within and between many bacterial species. However, its known receptors (LuxP and…”
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cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity
Published in The Journal of clinical investigation (01-11-2019)“…Checkpoint blockade antibodies have been approved as immunotherapy for multiple types of cancer, but the response rate and efficacy are still limited. There…”
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AHNAK Nucleoprotein 2 Performs a Promoting Role in the Proliferation and Migration of Uveal Melanoma Cells
Published in Cancer biotherapy & radiopharmaceuticals (01-12-2019)“…AHNAK nucleoprotein 2 (AHNAK2) is supposed to participate in calcium signaling and cytoarchitecture by directly interacting with some proteins. Recently, it…”
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Antifungal Activities of cis-trans Citral Isomers against Trichophyton rubrum with ERG6 as a Potential Target
Published in Molecules (Basel, Switzerland) (14-07-2021)“…Trichophyton rubrum causes ringworm worldwide. Citral (CIT), extracted from Pectis plants, is a monoterpene and naturally composed of geometric isomers neral…”
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6
RTA408 alleviates retinal ganglion cells damage in mouse glaucoma by inhibiting excessive autophagy
Published in PloS one (11-11-2024)“…Background Glaucoma, characterized by a high incidence and significant ocular harm, has been elucidated through various mechanisms. Excessive autophagy leading…”
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ENSO modulation of summertime tropospheric ozone over China
Published in Environmental research letters (01-03-2022)“…Abstract Ozone (O 3 ) is one of the most critical pollutants affecting air quality in China in recent years. In this study, different impacts of the El…”
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Clinical characteristics and prognosis analysis of acute symptomatic seizures secondary to autoimmune encephalitis
Published in Frontiers in neurology (30-10-2024)“…Objective This study aimed to analyze the clinical characteristics and prognosis of patients with autoimmune encephalitis (PWAE) who experienced seizures…”
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Thymic transcriptome analysis after Newcastle disease virus inoculation in chickens and the influence of host small RNAs on NDV replication
Published in Scientific reports (13-05-2021)“…Newcastle disease (ND), caused by virulent Newcastle disease virus (NDV), is a contagious viral disease affecting various birds and poultry worldwide. In this…”
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Motivational Climate Predicts Student Evaluations of Teaching: Relationships Between Students’ Course Perceptions, Ease of Course, and Evaluations of Teaching
Published in AERA open (01-02-2022)“…Student evaluations of teaching (SETs) are important at most colleges and universities. One purpose of this study was to determine the extent to which…”
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New skin tissue engineering scaffold with sulfated silk fibroin/chitosan/hydroxyapatite and its application
Published in Biochemical and biophysical research communications (15-01-2023)“…Repairing skin wounds has always been challenging in clinical practice. The new skin tissue engineering scaffold provides innovative ways to address these…”
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Molecular mechanism of valine and its metabolite in improving triglyceride synthesis of porcine intestinal epithelial cells
Published in Scientific reports (20-02-2023)“…An insufficient energy supply to intestinal epithelial cells decreases production performance in weaned piglets. Triglycerides are the main energy source for…”
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SeMet attenuates AFB1-induced intestinal injury in rabbits by activating the Nrf2 pathway
Published in Ecotoxicology and environmental safety (01-07-2022)“…The aim of this study was to investigate the role of selenomethionine (SeMet) in alleviating AFB1 induced intestinal injury by inhibiting intestinal oxidative…”
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14
Venetoclax and decitabine in refractory TP53-mutated early T-cell precursor acute lymphoblastic leukemia
Published in Annals of hematology (01-03-2022)Get full text
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Mevalonate Blockade in Cancer Cells Triggers CLEC9A + Dendritic Cell-Mediated Antitumor Immunity
Published in Cancer research (Chicago, Ill.) (01-09-2021)“…Hyperactive mevalonate (MVA) metabolic activity is often observed in cancer cells, and blockade of this pathway inhibits tumor cell lipid synthesis and cell…”
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Automated Extraction of Lake Water Bodies in Complex Geographical Environments by Fusing Sentinel-1/2 Data
Published in Water (Basel) (01-01-2022)“…Lakes are an important component of global water resources. Lake water bodies extraction based on satellite remote sensing mainly utilizes optical or radar…”
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Disparate macrophage responses are linked to infection outcome of Hantan virus in humans or rodents
Published in Nature communications (10-01-2024)“…Hantaan virus (HTNV) is asymptomatically carried by rodents, yet causes lethal hemorrhagic fever with renal syndrome in humans, the underlying mechanisms of…”
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Dexmedetomidine improved one-lung ventilation-induced cognitive dysfunction in rats
Published in BMC anesthesiology (23-04-2022)“…One-lung ventilation (OLV) is widely used in thoracic surgery. However, OLV may also increase CERO and aggravate delayed cognitive recovery. Here, we aimed to…”
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Cold protection allows local cryotherapy in a clinical-relevant model of traumatic optic neuropathy
Published in eLife (30-03-2022)“…Therapeutic hypothermia (TH) is potentially an important therapy for central nervous system (CNS) trauma. However, its clinical application remains…”
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LncRNA NEAT1 Potentiates SREBP2 Activity to Promote Inflammatory Macrophage Activation and Limit Hantaan Virus Propagation
Published in Frontiers in microbiology (13-04-2022)“…As the global prototypical zoonotic hantavirus, Hantaan virus (HTNV) is prevalent in Asia and is the leading causative agent of severe hemorrhagic fever with…”
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