Search Results - "Mengjie, Chen"

VIPER: variability-preserving imputation for accurate gene expression recovery in single-cell RNA sequencing studies by Chen, Mengjie, Zhou, Xiang

“…We develop a method, VIPER, to impute the zero values in single-cell RNA sequencing studies to facilitate accurate transcriptome quantification at the…”
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ROBUST COVARIANCE AND SCATTER MATRIX ESTIMATION UNDER HUBER’S CONTAMINATION MODEL by Chen, Mengjie, Gao, Chao, Ren, Zhao

“…Covariance matrix estimation is one of the most important problems in statistics. To accommodate the complexity of modern datasets, it is desired to have…”
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Demystifying "drop-outs" in single-cell UMI data by Kim, Tae Hyun, Zhou, Xiang, Chen, Mengjie

“…Many existing pipelines for scRNA-seq data apply pre-processing steps such as normalization or imputation to account for excessive zeros or "drop-outs." Here,…”
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Thermally Driven Structure and Performance Evolution of Atomically Dispersed FeN4 Sites for Oxygen Reduction by Li, Jiazhan, Zhang, Hanguang, Samarakoon, Widitha, Shan, Weitao, Cullen, David A., Karakalos, Stavros, Chen, Mengjie, Gu, Daming, More, Karren L., Wang, Guofeng, Feng, Zhenxing, Wang, Zhenbo, Wu, Gang

“…FeN4 moieties embedded in partially graphitized carbon are the most efficient platinum group metal free active sites for the oxygen reduction reaction in…”
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Nanocarbon/oxide composite catalysts for bifunctional oxygen reduction and evolution in reversible alkaline fuel cells: A mini review by Chen, Mengjie, Wang, Lei, Yang, Haipeng, Zhao, Shuai, Xu, Hui, Wu, Gang

“…A reversible fuel cell (RFC), which integrates a fuel cell with an electrolyzer, is similar to a rechargeable battery. This technology lies on high-performance…”
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Precious metal-free approach to hydrogen electrocatalysis for energy conversion: From mechanism understanding to catalyst design by Wang, Tanyuan, Xie, Huan, Chen, Mengjie, D'Aloia, Alyssa, Cho, Jaephil, Wu, Gang, Li, Qing

“…Hydrogen (H2) is the most promising green energy resources to replace conventional fossil fuels due to the high mass energy density and renewability. The…”
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m6A RNA modifications are measured at single-base resolution across the mammalian transcriptome by Hu, Lulu, Liu, Shun, Peng, Yong, Ge, Ruiqi, Su, Rui, Senevirathne, Chamara, Harada, Bryan T., Dai, Qing, Wei, Jiangbo, Zhang, Lisheng, Hao, Ziyang, Luo, Liangzhi, Wang, Huanyu, Wang, Yuru, Luo, Minkui, Chen, Mengjie, Chen, Jianjun, He, Chuan

“…Functional studies of the RNA N 6 -methyladenosine (m 6 A) modification have been limited by an inability to map individual m 6 A-modified sites in whole…”
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A meta-analysis of the relationship between vaginal microecology, human papillomavirus infection and cervical intraepithelial neoplasia by Liang, Yuejuan, Chen, Mengjie, Qin, Lu, Wan, Bing, Wang, He

“…Microecology is an emerging discipline in recent years. The female reproductive tract is an important microecological region, and its microecological…”
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Atomically dispersed manganese catalysts for oxygen reduction in proton-exchange membrane fuel cells by Li, Jiazhan, Chen, Mengjie, Cullen, David A., Hwang, Sooyeon, Wang, Maoyu, Li, Boyang, Liu, Kexi, Karakalos, Stavros, Lucero, Marcos, Zhang, Hanguang, Lei, Chao, Xu, Hui, Sterbinsky, George E., Feng, Zhenxing, Su, Dong, More, Karren L., Wang, Guofeng, Wang, Zhenbo, Wu, Gang

“…Platinum group metal (PGM)-free catalysts that are also iron free are highly desirable for the oxygen reduction reaction (ORR) in proton-exchange membrane fuel…”
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REPIC: a database for exploring the N 6 -methyladenosine methylome by Liu, Shun, Zhu, Allen, He, Chuan, Chen, Mengjie

“…The REPIC (RNA EPItranscriptome Collection) database records about 10 million peaks called from publicly available m A-seq and MeRIP-seq data using our unified…”
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Ternary PtIrNi Catalysts for Efficient Electrochemical Ammonia Oxidation by Li, Yi, Li, Xing, Pillai, Hemanth Somarajan, Lattimer, Judith, Mohd Adli, Nadia, Karakalos, Stavros, Chen, Mengjie, Guo, Lin, Xu, Hui, Yang, Juan, Su, Dong, Xin, Hongliang, Wu, Gang

“…Ammonia (NH3) has proved to be an effective alternative to hydrogen in low-temperature fuel cells via its direct ammonia oxidation reaction (AOR). However, the…”
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Integrative differential expression and gene set enrichment analysis using summary statistics for scRNA-seq studies by Ma, Ying, Sun, Shiquan, Shang, Xuequn, Keller, Evan T., Chen, Mengjie, Zhou, Xiang

“…Differential expression (DE) analysis and gene set enrichment (GSE) analysis are commonly applied in single cell RNA sequencing (scRNA-seq) studies. Here, we…”
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Immune infiltration and a ferroptosis-associated gene signature for predicting the prognosis of patients with endometrial cancer by Weijiao, Yin, Fuchun, Liao, Mengjie, Chen, Xiaoqing, Qin, Hao, Lai, Yuan, Lin, Desheng, Yao

“…Ferroptosis, a form of programmed cell death induced by excess iron-dependent lipid peroxidation product accumulation, plays a critical role in cancer…”
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Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations by Chang, Jiang, Tan, Wenle, Ling, Zhiqiang, Xi, Ruibin, Shao, Mingming, Chen, Mengjie, Luo, Yingying, Zhao, Yanjie, Liu, Yun, Huang, Xiancong, Xia, Yuchao, Hu, Jinlin, Parker, Joel S., Marron, David, Cui, Qionghua, Peng, Linna, Chu, Jiahui, Li, Hongmin, Du, Zhongli, Han, Yaling, Tan, Wen, Liu, Zhihua, Zhan, Qimin, Li, Yun, Mao, Weimin, Wu, Chen, Lin, Dongxin

“…Approximately half of the world’s 500,000 new oesophageal squamous-cell carcinoma (ESCC) cases each year occur in China. Here, we show whole-genome sequencing…”
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Integrins regulate stemness in solid tumor: an emerging therapeutic target by Xiong, Jiangling, Yan, Lianlian, Zou, Cheng, Wang, Kai, Chen, Mengjie, Xu, Bin, Zhou, Zhipeng, Zhang, Dingxiao

“…Abstract Integrins are the adhesion molecules and transmembrane receptors that consist of α and β subunits. After binding to extracellular matrix components,…”
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Circular RNA circMYBPC1 promotes skeletal muscle differentiation by targeting MyHC by Chen, Mengjie, Wei, Xuefeng, Song, Mingming, Jiang, Rui, Huang, Kongwei, Deng, Yanfei, Liu, Qingyou, Shi, Deshun, Li, Hui

“…Skeletal muscle development is a complex and highly orchestrated biological process mediated by a series of myogenesis regulatory factors. Numerous studies…”
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Paclitaxel-loaded silk fibroin nanospheres by Chen, Mengjie, Shao, Zhengzhong, Chen, Xin

“…Silk fibroin is a very promising biomedical material because of its renewability, nontoxicity, biocompatibility, and biodegradability. On the basis of a simple…”
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RADAR: differential analysis of MeRIP-seq data with a random effect model by Zhang, Zijie, Zhan, Qi, Eckert, Mark, Zhu, Allen, Chryplewicz, Agnieszka, De Jesus, Dario F, Ren, Decheng, Kulkarni, Rohit N, Lengyel, Ernst, He, Chuan, Chen, Mengjie

“…Epitranscriptome profiling using MeRIP-seq is a powerful technique for in vivo functional studies of reversible RNA modifications. We develop RADAR, a…”
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The risk and latency evaluation of secondary primary malignancies of cervical cancer patients who received radiotherapy: A study based on the SEER database by Chen, Mengjie, Pan, Xinbin, Wang, He, Yao, Desheng

“…To study the risk factors for the onset of secondary primary malignancies (SPM) and the latency between SPM and cervical cancer after radiotherapy. We selected…”
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Case report: Brachial plexopathy caused by malignant peripheral nerve sheath tumor and review of the literature by Chen, Mengjie, Li, Xiuli, Feng, Xinhong

“…Brachial plexopathy (BP) is easily misdiagnosed due to its complexity and varying clinical presentation. Malignant peripheral nerve sheath tumors (MPNST) can…”
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