Search Results - "Menger, Marcus M"

The use of high-affinity polyhistidine binders as masking probes for the selection of an NDM-1 specific aptamer by Sabrowski, Wiebke, Dreymann, Nico, Möller, Anja, Czepluch, Denise, Albani, Patricia P., Theodoridis, Dimitrios, Menger, Marcus M.

“…The emergence of carbapenemase-producing multi-drug resistant Enterobacteriaceae poses a dramatic, world-wide health risk. Limited treatment options and a lack…”
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Inhibition of Human Urokinase-Type Plasminogen Activator (uPA) Enzyme Activity and Receptor Binding by DNA Aptamers as Potential Therapeutics through Binding to the Different Forms of uPA by Dreymann, Nico, Wuensche, Julia, Sabrowski, Wiebke, Moeller, Anja, Czepluch, Denise, Vu Van, Dana, Fuessel, Susanne, Menger, Marcus M

“…Urokinase-type plasminogen activator is widely discussed as a marker for cancer prognosis and diagnosis and as a target for cancer therapies. Together with its…”
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Enhancing Colorimetric Detection of Nucleic Acids on Nitrocellulose Membranes: Cutting-Edge Applications in Diagnostics and Forensics by Subhashini, Nidhi, Kerler, Yannick, Menger, Marcus M, Böhm, Olga, Witte, Judith, Stadler, Christian, Griberman, Alexander

“…This study re-introduces a protein-free rapid test method for nucleic acids on paper based lateral flow assays utilizing special multichannel nitrocellulose…”
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Markedly divergent effects of Ouabain on a Temozolomide-resistant (T98G) vs. a Temozolomide-sensitive (LN229) Glioblastoma cell line by Weidemann, Heidrun, Feger, Daniel, Ehlert, Jan E., Menger, Marcus M., Krempien, Robert C.

“…Background Glioblastoma multiforme (GBM) is the most aggressive primary brain tumor with poor prognosis. GMB are highly recurrent mainly because of radio- and…”
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Aptamer-Based Sandwich Assay Formats for Detection and Discrimination of Human High- and Low-Molecular-Weight uPA for Cancer Prognosis and Diagnosis by Dreymann, Nico, Sabrowski, Wiebke, Danso, Jennifer, Menger, Marcus M

“…Urokinase-type plasminogen activator (urokinase, uPA) is a frequently discussed biomarker for prognosis, diagnosis, and recurrence of cancer. In a previous…”
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Label-Free Determination of the Kinetic Parameters of Protein-Aptamer Interaction by Surface Plasmon Resonance by Dreymann, Nico, Möller, Anja, Menger, Marcus M

“…Due to their high specificity and affinity to target molecules, aptamers can be used as powerful tools in diagnostics, therapeutics, and environmental or food…”
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Determination of Aptamer Structure Using Circular Dichroism Spectroscopy by Kerler, Yannick, Sass, Stephan, Hille, Carsten, Menger, Marcus M

“…G-quadruplexes can be important as three-dimensional structures for aptamers as they improve the properties of the nucleic acids like higher nuclease…”
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Immobilization-Free Determination of Dissociation Constants Independent of Ligand Size Using MicroScale Thermophoresis by Sabrowski, Wiebke, Stöcklein, Walter F M, Menger, Marcus M

“…The quantitative characterization of aptamer-ligand interactions is an important step in the aptamer development process. However, certain pitfalls impede K…”
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Molekularer Abdruck oder Selektion bei der Erzeugung biomimetischer Specifyer by Menger, Marcus M., Yarman, Aysu, Oktay, Aysel, Scheller, Frieder W.

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Molekularer Abdruck oder Selektion bei der Erzeugung biomimetischer Specifyer by Menger, Marcus M., Yarman, Aysu, Oktay, Aysel, Scheller, Frieder W.

“…Abstract Aptamers and imprinted polymers (MIPs) for the recognition of low-molecular substances, proteins, nucleic acids, viruses and cells have been developed…”
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