Search Results - "Mengatto, Luisa"

Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models by Sasso, Oscar, Moreno-Sanz, Guillermo, Martucci, Cataldo, Realini, Natalia, Dionisi, Mauro, Mengatto, Luisa, Duranti, Andrea, Tarozzo, Glauco, Tarzia, Giorgio, Mor, Marco, Bertorelli, Rosalia, Reggiani, Angelo, Piomelli, Daniele

“…The N-acylethanolamine acid amidase inhibitor ARN077 exerts profound antinociceptive effects in animal pain models by enhancing endogenous lipid signaling at…”
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Synthesis and Structure–Activity Relationship (SAR) of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors by Ponzano, Stefano, Bertozzi, Fabio, Mengatto, Luisa, Dionisi, Mauro, Armirotti, Andrea, Romeo, Elisa, Berteotti, Anna, Fiorelli, Claudio, Tarozzo, Glauco, Reggiani, Angelo, Duranti, Andrea, Tarzia, Giorgio, Mor, Marco, Cavalli, Andrea, Piomelli, Daniele, Bandiera, Tiziano

“…N-Acylethanolamine acid amidase (NAAA) is a lysosomal cysteine hydrolase involved in the degradation of saturated and monounsaturated fatty acid ethanolamides…”
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Selective Inhibitors of G2019S-LRRK2 Kinase Activity by Garofalo, Albert W, Bright, Jessica, De Lombaert, Stéphane, Toda, Alyssa M. A, Zobel, Kerry, Andreotti, Daniele, Beato, Claudia, Bernardi, Silvia, Budassi, Federica, Caberlotto, Laura, Gao, Peng, Griffante, Cristiana, Liu, Xinying, Mengatto, Luisa, Migliore, Marco, Sabbatini, Fabio Maria, Sava, Anna, Serra, Elena, Vincetti, Paolo, Zhang, Mingliang, Carlisle, Holly J

“…Pathogenic variants in the leucine-rich repeat kinase 2 (LRRK2) gene have been identified that increase the risk for developing Parkinson’s disease in a…”
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Discovery and SAR Evolution of Pyrazole Azabicyclo[3.2.1]octane Sulfonamides as a Novel Class of Non-Covalent N‑Acylethanolamine-Hydrolyzing Acid Amidase (NAAA) Inhibitors for Oral Administration by Di Fruscia, Paolo, Carbone, Anna, Bottegoni, Giovanni, Berti, Francesco, Giacomina, Francesca, Ponzano, Stefano, Pagliuca, Chiara, Fiasella, Annalisa, Pizzirani, Daniela, Ortega, Jose Antonio, Nuzzi, Andrea, Tarozzo, Glauco, Mengatto, Luisa, Giampà, Roberta, Penna, Ilaria, Russo, Debora, Romeo, Elisa, Summa, Maria, Bertorelli, Rosalia, Armirotti, Andrea, Bertozzi, Sine Mandrup, Reggiani, Angelo, Bandiera, Tiziano, Bertozzi, Fabio

“…Inhibition of intracellular N-acylethanolamine-hydrolyzing acid amidase (NAAA) activity is a promising approach to manage the inflammatory response under…”
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A Potent Systemically Active N‑Acylethanolamine Acid Amidase Inhibitor that Suppresses Inflammation and Human Macrophage Activation by Ribeiro, Alison, Pontis, Silvia, Mengatto, Luisa, Armirotti, Andrea, Chiurchiù, Valerio, Capurro, Valeria, Fiasella, Annalisa, Nuzzi, Andrea, Romeo, Elisa, Moreno-Sanz, Guillermo, Maccarrone, Mauro, Reggiani, Angelo, Tarzia, Giorgio, Mor, Marco, Bertozzi, Fabio, Bandiera, Tiziano, Piomelli, Daniele

“…Fatty acid ethanolamides such as palmitoylethanolamide (PEA) and oleoylethanolamide (OEA) are lipid-derived mediators that potently inhibit pain and…”
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Synthesis, Biological Evaluation, and 3D QSAR Study of 2‑Methyl-4-oxo-3-oxetanylcarbamic Acid Esters as N‑Acylethanolamine Acid Amidase (NAAA) Inhibitors by Ponzano, Stefano, Berteotti, Anna, Petracca, Rita, Vitale, Romina, Mengatto, Luisa, Bandiera, Tiziano, Cavalli, Andrea, Piomelli, Daniele, Bertozzi, Fabio, Bottegoni, Giovanni

“…N-(2-Oxo-3-oxetanyl)carbamic acid esters have recently been reported to be noncompetitive inhibitors of the N-acylethanolamine acid amidase (NAAA) potentially…”
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Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase by Pizzirani, Daniela, Bach, Anders, Realini, Natalia, Armirotti, Andrea, Mengatto, Luisa, Bauer, Inga, Girotto, Stefania, Pagliuca, Chiara, De Vivo, Marco, Summa, Maria, Ribeiro, Alison, Piomelli, Daniele

“…The ceramides are a family of bioactive lipid‐derived messengers involved in the control of cellular senescence, inflammation, and apoptosis. Ceramide…”
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Inside Cover: Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase (Angew. Chem. Int. Ed. 2/2015) by Pizzirani, Daniela, Bach, Anders, Realini, Natalia, Armirotti, Andrea, Mengatto, Luisa, Bauer, Inga, Girotto, Stefania, Pagliuca, Chiara, De Vivo, Marco, Summa, Maria, Ribeiro, Alison, Piomelli, Daniele

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β-Lactones Inhibit N-acylethanolamine Acid Amidase by S-Acylation of the Catalytic N-Terminal Cysteine by Armirotti, Andrea, Romeo, Elisa, Ponzano, Stefano, Mengatto, Luisa, Dionisi, Mauro, Karacsonyi, Claudia, Bertozzi, Fabio, Garau, Gianpiero, Tarozzo, Glauco, Reggiani, Angelo, Bandiera, Tiziano, Tarzia, Giorgio, Mor, Marco, Piomelli, Daniele

“…The cysteine amidase N-acylethanolamine acid amidase (NAAA) is a member of the N-terminal nucleophile class of enzymes and a potential target for…”
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Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase by Pizzirani, Daniela, Bach, Anders, Realini, Natalia, Armirotti, Andrea, Mengatto, Luisa, Bauer, Inga, Girotto, Stefania, Pagliuca, Chiara, De Vivo, Marco, Summa, Maria, Ribeiro, Alison, Piomelli, Daniele

“…The ceramides are a family of bioactive lipid‐derived messengers involved in the control of cellular senescence, inflammation, and apoptosis. Ceramide…”
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Innentitelbild: Benzoxazolone Carboxamides: Potent and Systemically Active Inhibitors of Intracellular Acid Ceramidase (Angew. Chem. 2/2015) by Pizzirani, Daniela, Bach, Anders, Realini, Natalia, Armirotti, Andrea, Mengatto, Luisa, Bauer, Inga, Girotto, Stefania, Pagliuca, Chiara, De Vivo, Marco, Summa, Maria, Ribeiro, Alison, Piomelli, Daniele

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