Search Results - "Meng Looi, Lai"
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The Lancet Commission on diagnostics: transforming access to diagnostics
Published in The Lancet (British edition) (27-11-2021)“…[...]the publication of an essential diagnostics list (EDL) for priority settings by WHO in 2018 has been a key step in recognising the importance of…”
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The Top 25 Laboratory Tests by Volume and Revenue in Five Different Countries
Published in American journal of clinical pathology (02-04-2019)“…Abstract Objectives To compare the most common diagnostic/laboratory tests across five different referral hospitals by volume and revenue. Methods The authors…”
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A review on omics-based biomarkers discovery for Alzheimer's disease from the bioinformatics perspectives: Statistical approach vs machine learning approach
Published in Computers in biology and medicine (01-12-2021)“…Alzheimer's Disease (AD) is a neurodegenerative disease that affects cognition and is the most common cause of dementia in the elderly. As the number of…”
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A multi-ethnic proteomic profiling analysis in Alzheimer's disease identifies the disparities in dysregulation of proteins and pathogenesis
Published in PeerJ (San Francisco, CA) (18-07-2024)“…Alzheimer's disease (AD) is the most common type of dementia that affects the elderly population. Lately, blood-based proteomics have been intensively sought…”
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Clustering of HR + /HER2- breast cancer in an Asian cohort is driven by immune phenotypes
Published in Breast cancer research : BCR (22-04-2024)“…Breast cancer exhibits significant heterogeneity, manifesting in various subtypes that are critical in guiding treatment decisions. This study aimed to…”
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The classification of glomerulonephritis in systemic lupus erythematosus revisited
Published in Journal of the American Society of Nephrology (01-02-2004)“…The currently used classification reflects our understanding of the pathogenesis of the various forms of lupus nephritis, but clinicopathologic studies have…”
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Potential utility of telomere length assessment in breast cancer in a diagnostic histopathology setting
Published in Malaysian journal of pathology (01-04-2023)“…Telomeres shorten with cell cycling but are restored above mortality threshold in many cancers making them potentially exploitable for differentiating…”
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Propylthiouracil-Induced Antineutrophil Cytoplasmic Antibodies-Associated Vasculitis with Renal and Lung Involvement
Published in Case reports in nephrology and dialysis (17-06-2022)“…Propylthiouracil (PTU)-induced antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) is a rare and heterogeneous disease. Moreover, optimal…”
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Usefulness of a scoring system in the interpretation of histology in neonatal cholestasis
Published in World journal of gastroenterology : WJG (14-11-2009)“…AIM: To ascertain the usefulness of a histological scoring system devised to assist in the interpretation of liver histology in neonatal cholestasis (NC)…”
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Assessment of Telomere Length in Archived Formalin-Fixed, Paraffinized Human Tissue Is Confounded by Chronological Age and Storage Duration
Published in PloS one (06-09-2016)“…Telomeres shorten with physiological aging but undergo substantial restoration during cancer immortalization. Increasingly, cancer studies utilize the archive…”
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Differential Expression Analysis of Blood MicroRNA in Identifying Potential Genes Relevant to Alzheimer’s Disease Pathogenesis, Using an Integrated Bioinformatics and Machine Learning Approach
Published in Applied sciences (01-02-2023)“…Alzheimer’s disease (AD) is a neurodegenerative disease characterized by cognitive and functional impairment. Recent research has focused on the deregulation…”
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Multi-Configuration Analysis of DenseNet Architecture for Whole Slide Image Scoring of ER-IHC
Published in IEEE access (2023)“…Nuclei classification is a mandatory process to obtain scoring information for whole slide images (WSIs). In immunohistochemistry (IHC) staining specifically…”
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Access to pathology and laboratory medicine services: a crucial gap
Published in The Lancet (British edition) (12-05-2018)“…As global efforts accelerate to implement the Sustainable Development Goals and, in particular, universal health coverage, access to high-quality and timely…”
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14
Adjuvant! Online is overoptimistic in predicting survival of Asian breast cancer patients
Published in European journal of cancer (1990) (01-05-2012)“…Abstract Background: Adjuvant! Online is a free web-based tool which predicts 10-year breast cancer outcomes and the efficacy of adjuvant therapy in patients…”
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HER2-Sish Histopathology Image Classification Using Deep Neural Networks
Published in 2023 IEEE International Conference on Image Processing (ICIP) (08-10-2023)“…The status of the human epidermal growth factor receptor 2 (HER2) gene amplification is an important marker for assessing the efficacy of clinical treatments…”
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Conference Proceeding -
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Esophageal squamous cell carcinomas in a Malaysian cohort show a lack of association with human papillomavirus
Published in Journal of digestive diseases (01-05-2018)“…OBJECTIVE With an age‐standardized incidence rate of 2 per 100 000, esophageal cancer is not common among Malaysians, but they are nevertheless important due…”
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DNA mismatch repair and CD133-marked cancer stem cells in colorectal carcinoma
Published in PeerJ (San Francisco, CA) (11-09-2018)“…Except for a few studies with contradictory observations, information is lacking on the possibility of association between DNA mismatch repair (MMR) status and…”
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Delivering modern, high-quality, affordable pathology and laboratory medicine to low-income and middle-income countries: a call to action
Published in The Lancet (British edition) (12-05-2018)“…Modern, affordable pathology and laboratory medicine (PALM) systems are essential to achieve the 2030 Sustainable Development Goals for health in low-income…”
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Does the axillary lymph node ratio have any added prognostic value over pN staging for South East Asian breast cancer patients?
Published in PloS one (24-09-2012)“…Lymph node ratio (LNR, i.e. the ratio of the number of positive nodes to the total number of nodes excised) is reported to be superior to the absolute number…”
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Improving pathology and laboratory medicine in low-income and middle-income countries: roadmap to solutions
Published in The Lancet (British edition) (12-05-2018)“…Insufficient awareness of the centrality of pathology and laboratory medicine (PALM) to a functioning health-care system at policy and governmental level, with…”
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Journal Article