Search Results - "Meng, Xianli"

Upconversion NIR-II fluorophores for mitochondria-targeted cancer imaging and photothermal therapy by Zhou, Hui, Zeng, Xiaodong, Li, Anguo, Zhou, Wenyi, Tang, Lin, Hu, Wenbo, Fan, Quli, Meng, Xianli, Deng, Hai, Duan, Lian, Li, Yanqin, Deng, Zixin, Hong, Xuechuan, Xiao, Yuling

“…NIR-II fluorophores have shown great promise for biomedical applications with superior in vivo optical properties. To date, few small-molecule NIR-II…”
Get full text

Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases by Bai, Jinrong, Zhang, Yunsen, Tang, Ce, Hou, Ya, Ai, Xiaopeng, Chen, Xiaorui, Zhang, Yi, Wang, Xiaobo, Meng, Xianli

“…[Display omitted] Gallic acid (GA), also known as 3,4,5-trihydroxybenzoic acid, is a natural secondary metabolite and widely isolated from various fruits,…”
Get full text

Versatile Types of Inorganic/Organic NIR-IIa/IIb Fluorophores: From Strategic Design toward Molecular Imaging and Theranostics by Liu, Yishen, Li, Yang, Koo, Seyoung, Sun, Yao, Liu, Yixuan, Liu, Xing, Pan, Yanna, Zhang, Zhiyun, Du, Mingxia, Lu, Siyu, Qiao, Xue, Gao, Jianfeng, Wang, Xiaobo, Deng, Zixin, Meng, Xianli, Xiao, Yuling, Kim, Jong Seung, Hong, Xuechuan

“…In vivo imaging in the second near-infrared window (NIR-II, 1000–1700 nm), which enables us to look deeply into living subjects, is producing marvelous…”
Get full text

Pyroptosis by caspase-11 inflammasome-Gasdermin D pathway in autoimmune diseases by Wu, Jiasi, Sun, Jiayi, Meng, Xianli

“…[Display omitted] •Caspase-11 engaged in the crosstalk between innate and adaptive immune response.•Caspase-11 activation implicates in the pathogenesis of…”
Get full text

Molecular Simulation Elaborating the Mechanism of 1β-Hydroxy Alantolactone Inhibiting Ubiquitin-Conjugating Enzyme UbcH5s by Xu, Youdong, Meng, Xianli

“…1β-hydroxy alantolactone, a sesquiterpene lactone, exhibits potent anti-inflammatory and anticancer activities. Recently, it has been found to target UbcH5s by…”
Get full text

A Comprehensive Review on the Chemical Properties, Plant Sources, Pharmacological Activities, Pharmacokinetic and Toxicological Characteristics of Tetrahydropalmatine by Du, Qinyun, Meng, Xianli, Wang, Shaohui

“…Tetrahydropalmatine (THP), a tetrahydroproberine isoquinoline alkaloid, is widely present in some botanical drugs, such as H.S. Lo (Menispermaceae; Radix…”
Get full text

Novel NIR-II organic fluorophores for bioimaging beyond 1550 nm by Li, Yang, Liu, Yufang, Li, Qianqian, Zeng, Xiaodong, Tian, Tian, Zhou, Wenyi, Cui, Yan, Wang, Xikun, Cheng, Xiaoding, Ding, Qihang, Wang, Xiaofei, Wu, Junzhu, Deng, Hai, Li, Yanqin, Meng, Xianli, Deng, Zixin, Hong, Xuechuan, Xiao, Yuling

“…Near-infrared fluorescence imaging in the 1500-1700 nm sub-window (NIR-IIb) has shown a deeper penetration depth, higher resolution and zero auto-fluorescence…”
Get full text

Salidroside as a potential neuroprotective agent for ischemic stroke: a review of sources, pharmacokinetics, mechanism and safety by Fan, Fangfang, Yang, Lu, Li, Rui, Zou, Xuemei, Li, Ning, Meng, Xianli, Zhang, Yi, Wang, Xiaobo

“…[Display omitted] •Comprehensively reviewed the natural sources and synthetic pathways of Salidroside.•Delineated pharmacokinetics, BBB permeability and safety…”
Get full text

To Elucidate the Inhibition of Excessive Autophagy of Rhodiola crenulata on Exhaustive Exercise-Induced Skeletal Muscle Injury by Combined Network Pharmacology and Molecular Docking by Li, Xuanhao, Hou, Ya, Wang, Xiaobo, Zhang, Ying, Meng, Xianli, Hu, Yao, Zhang, Yi

“…Autophagy can remodel skeletal muscle in response to exercise. However, excessive autophagy can have adverse effects on skeletal muscle. Although Rhodiola…”
Get full text

Targeting foam cell formation and macrophage polarization in atherosclerosis: The Therapeutic potential of rhubarb by Liu, Xianfeng, Wu, Jiasi, Tian, Ruimin, Su, Siyu, Deng, Siang, Meng, Xianli

“…[Display omitted] •Targeting macrophage polarization is a potential therapeutic strategy for atherosclerosis.•Inhibiting foam cell formation is a promising way…”
Get full text

Cytokine storm-calming property of the isoquinoline alkaloids in Coptis chinensis Franch by Lan, Yuejia, Wang, Huan, Wu, Jiasi, Meng, Xianli

“…Coronavirus disease (COVID-19) has spread worldwide and its effects have been more devastating than any other infectious disease. Importantly, patients with…”
Get full text

Comprehensive bioinformatics analysis to identify a novel cuproptosis-related prognostic signature and its ceRNA regulatory axis and candidate traditional Chinese medicine active ingredients in lung adenocarcinoma by Wang, Shaohui, Xing, Nan, Meng, Xianli, Xiang, Li, Zhang, Yi

“…Lung adenocarcinoma (LUAD) is the most ordinary histological subtype of lung cancer, and regulatory cell death is an attractive target for cancer therapy…”
Get full text

Berberine: A Review of its Pharmacokinetics Properties and Therapeutic Potentials in Diverse Vascular Diseases by Ai, Xiaopeng, Yu, Peiling, Peng, Lixia, Luo, Liuling, Liu, Jia, Li, Shengqian, Lai, Xianrong, Luan, Fei, Meng, Xianli

“…Traditional Chinese medicine plays a significant role in the treatment of various diseases and has attracted increasing attention for clinical applications…”
Get full text

A review of traditional Chinese medicine on treatment of diabetic retinopathy and involved mechanisms by Ai, Xiaopeng, Yu, Peiling, Hou, Ya, Song, Xinchen, Luo, Jie, Li, Ning, Lai, Xianrong, Wang, Xiaobo, Meng, Xianli

“…[Display omitted] •We summarized and analyzed the prescriptions, herbs and identified compounds of TCM on the treatment of DR from the aspects of…”
Get full text

Coptisine from Coptis chinensis blocks NLRP3 inflammasome activation by inhibiting caspase-1 by Wu, Jiasi, Luo, Yu, Jiang, Qing, Li, Sheng, Huang, Wenge, Xiang, Li, Liu, Deming, Hu, Yingfan, Wang, Ping, Lu, Xiaoxia, Zhang, Guolin, Wang, Fei, Meng, Xianli

“…Coptisine prevents caspase-1 activity, leading to NLRP3 inflammasome disassembly and decreased secretion of IL-1β and IL-18. Coptisine also suppresses the…”
Get full text

The enhanced mitochondrial dysfunction by cantleyoside confines inflammatory response and promotes apoptosis of human HFLS-RA cell line via AMPK/Sirt 1/NF-κB pathway activation by Bai, Jinrong, Xie, Na, Hou, Ya, Chen, Xiaorui, Hu, Yao, Zhang, Yi, Meng, Xianli, Wang, Xiaobo, Tang, Ce

“…Cantleyoside (CA) is a kind of iridoid glycosides in Pterocephalus hookeri (C. B. Clarke) Höeck. The purpose of this study was to investigate the effects of CA…”
Get full text

Potential applications of microfluidics based blood brain barrier (BBB)-on-chips for in vitro drug development by Wang, Xiaobo, Hou, Ya, Ai, Xiaopeng, Sun, Jiayi, Xu, Binjie, Meng, Xianli, Zhang, Yi, Zhang, Sanyin

“…[Display omitted] •Microfluidic BBB chips composed of brain microvascular endothelial cells, pericytes, astrocytes and multifarious neurons can simulate the…”
Get full text

Mitochondrial MPTP: A Novel Target of Ethnomedicine for Stroke Treatment by Apoptosis Inhibition by Li, Yangxin, Sun, Jiayi, Wu, Ruixia, Bai, Jinrong, Hou, Ya, Zeng, Yong, Zhang, Yi, Wang, Xiaobo, Wang, Zhang, Meng, Xianli

“…Mammalian mitochondrial permeability transition pore (MPTP), across the inner and outer membranes of mitochondria, is a nonspecific channel for signal…”
Get full text

An Updated Meta-Analysis Based on the Preclinical Evidence of Mechanism of Aconitine-Induced Cardiotoxicity by Jiang, Hong, Zhang, Yating, Zhang, Yi, Wang, Xiaobo, Meng, Xianli

“…Most species in traditional Chinese medicine have the effect of dispelling wind, dehumidifying, warming the meridian, and relieving pain. Aconitine is the…”
Get full text

Scutellarin ameliorates mitochondrial dysfunction and apoptosis in OGD/R-insulted HT22 cells through mitophagy induction by Yang, Lu, Liu, Xianfeng, Chen, Siyin, Sun, Jiayi, Tao, Yiwen, Ma, liyuan, Zeng, Yong, Luo, Kaipei, Tian, Ruimin, Meng, Xianli

“…Scutellarin (Scu), a flavonoid from herbal Erigeron breviscapus (Vaniot) Hand-Mazz, exerts neuroprotective effects against cerebral ischemia. However, whether…”
Get full text