Search Results - "Meng, Qingcai"

Ferroptosis, necroptosis, and pyroptosis in anticancer immunity by Tang, Rong, Xu, Jin, Zhang, Bo, Liu, Jiang, Liang, Chen, Hua, Jie, Meng, Qingcai, Yu, Xianjun, Shi, Si

“…In recent years, cancer immunotherapy based on immune checkpoint inhibitors (ICIs) has achieved considerable success in the clinic. However, ICIs are…”
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Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives by Mao, Xiaoqi, Xu, Jin, Wang, Wei, Liang, Chen, Hua, Jie, Liu, Jiang, Zhang, Bo, Meng, Qingcai, Yu, Xianjun, Shi, Si

“…Cancer-associated fibroblasts (CAFs), a stromal cell population with cell-of-origin, phenotypic and functional heterogeneity, are the most essential components…”
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TRIM14 Inhibits cGAS Degradation Mediated by Selective Autophagy Receptor p62 to Promote Innate Immune Responses by Chen, Meixin, Meng, Qingcai, Qin, Yunfei, Liang, Puping, Tan, Peng, He, Lian, Zhou, Yubin, Chen, Yongjun, Huang, Junjiu, Wang, Rong-Fu, Cui, Jun

“…Cyclic GMP-AMP synthase (cGAS) is an essential DNA virus sensor that triggers type I interferon (IFN) signaling by producing cGAMP to initiate antiviral…”
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PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications by Zhu, Heng, Wei, Miaoyan, Xu, Jin, Hua, Jie, Liang, Chen, Meng, Qingcai, Zhang, Yiyin, Liu, Jiang, Zhang, Bo, Yu, Xianjun, Shi, Si

“…Pancreatic cancer is a highly lethal disease with a poor prognosis, and existing therapies offer only limited effectiveness. Mutation gene sequencing has shown…”
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Complex roles of the stroma in the intrinsic resistance to gemcitabine in pancreatic cancer: where we are and where we are going by Liang, Chen, Shi, Si, Meng, Qingcai, Liang, Dingkong, Ji, Shunrong, Zhang, Bo, Qin, Yi, Xu, Jin, Ni, Quanxing, Yu, Xianjun

“…Pancreatic ductal adenocarcinoma (PDAC) is among the most devastating human malignancies. The poor clinical outcome in PDAC is partly attributed to a…”
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The reciprocal regulation between host tissue and immune cells in pancreatic ductal adenocarcinoma: new insights and therapeutic implications by Liu, Xiaomeng, Xu, Jin, Zhang, Bo, Liu, Jiang, Liang, Chen, Meng, Qingcai, Hua, Jie, Yu, Xianjun, Shi, Si

“…Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death and is one of the most difficult-to-treat cancers. Surgical…”
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Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis by Rong, Zeyin, Shi, Si, Tan, Zhen, Xu, Jin, Meng, Qingcai, Hua, Jie, Liu, Jiang, Zhang, Bo, Wang, Wei, Yu, Xianjun, Liang, Chen

“…Extensive studies have demonstrated the pivotal roles of circular RNAs (circRNAs) in the occurrence and development of different human cancers. However, the…”
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Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2) by Xia, Guanggai, Wang, Hongcheng, Song, Ziliang, Meng, Qingcai, Huang, Xiuyan, Huang, Xinyu

“…Pancreatic cancer is susceptible to gemcitabine resistance, and patients receive less benefit from gemcitabine chemotherapy. Previous studies report that…”
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Overcoming chemoresistance by targeting reprogrammed metabolism: the Achilles' heel of pancreatic ductal adenocarcinoma by Tuerhong, Abudureyimu, Xu, Jin, Shi, Si, Tan, Zhen, Meng, Qingcai, Hua, Jie, Liu, Jiang, Zhang, Bo, Wang, Wei, Yu, Xianjun, Liang, Chen

“…Pancreatic ductal adenocarcinoma (PDAC) is one of the leading causes of cancer-related death due to its late diagnosis that removes the opportunity for surgery…”
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Circular RNA in pancreatic cancer: a novel avenue for the roles of diagnosis and treatment by Rong, Zeyin, Xu, Jin, Shi, Si, Tan, Zhen, Meng, Qingcai, Hua, Jie, Liu, Jiang, Zhang, Bo, Wang, Wei, Yu, Xianjun, Liang, Chen

“…Pancreatic cancer (PC), an important cause of cancer-related deaths worldwide, is one of the most malignant cancers characterized by a dismal prognosis…”
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Ferroptosis: At the Crossroad of Gemcitabine Resistance and Tumorigenesis in Pancreatic Cancer by Yang, Jianhui, Xu, Jin, Zhang, Bo, Tan, Zhen, Meng, Qingcai, Hua, Jie, Liu, Jiang, Wang, Wei, Shi, Si, Yu, Xianjun, Liang, Chen

“…The overall five-year survival rate of pancreatic cancer has hardly changed in the past few decades (less than 10%) because of resistance to all known…”
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PIN1 Maintains Redox Balance via the c-Myc/NRF2 Axis to Counteract Kras-Induced Mitochondrial Respiratory Injury in Pancreatic Cancer Cells by Liang, Chen, Shi, Si, Liu, Mingyang, Qin, Yi, Meng, Qingcai, Hua, Jie, Ji, Shunrong, Zhang, Yuqing, Yang, Jingxuan, Xu, Jin, Ni, Quanxing, Li, Min, Yu, Xianjun

“…: Kras is a decisive oncogene in pancreatic ductal adenocarcinoma (PDAC). PIN1 is a key effector involved in the Kras/ERK axis, synergistically mediating…”
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Signaling pathways in cancer‐associated fibroblasts: recent advances and future perspectives by Fang, Zengli, Meng, Qingcai, Xu, Jin, Wang, Wei, Zhang, Bo, Liu, Jiang, Liang, Chen, Hua, Jie, Zhao, Yingjun, Yu, Xianjun, Shi, Si

“…As a critical component of the tumor microenvironment (TME), cancer‐associated fibroblasts (CAFs) play important roles in cancer initiation and progression…”
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The role of m6A-related genes in the prognosis and immune microenvironment of pancreatic adenocarcinoma by Tang, Rong, Zhang, Yiyin, Liang, Chen, Xu, Jin, Meng, Qingcai, Hua, Jie, Liu, Jiang, Zhang, Bo, Yu, Xianjun, Shi, Si

“…Pancreatic adenocarcinoma (PAAD) is among the most lethal diseases and has a dismal prognosis; however, efficient treatment is currently limited. Several…”
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The promising role of noncoding RNAs in cancer-associated fibroblasts: an overview of current status and future perspectives by Fang, Zengli, Xu, Jin, Zhang, Bo, Wang, Wei, Liu, Jiang, Liang, Chen, Hua, Jie, Meng, Qingcai, Yu, Xianjun, Shi, Si

“…As the most important component of the stromal cell population in the tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) are crucial players in…”
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RNA N6-methyladenosine demethylase FTO promotes pancreatic cancer progression by inducing the autocrine activity of PDGFC in an m6A-YTHDF2-dependent manner by Tan, Zhen, Shi, Si, Xu, Jin, Liu, Xiaomeng, Lei, Yubin, Zhang, Bo, Hua, Jie, Meng, Qingcai, Wang, Wei, Yu, Xianjun, Liang, Chen

“…RNA N6-methyladenosine (m 6 A) is an emerging regulator of mRNA modifications and represents a novel player in tumorigenesis. Although it has functional…”
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Deciphering the Prognostic Implications of the Components and Signatures in the Immune Microenvironment of Pancreatic Ductal Adenocarcinoma by Tang, Rong, Liu, Xiaomeng, Liang, Chen, Hua, Jie, Xu, Jin, Wang, Wei, Meng, Qingcai, Liu, Jiang, Zhang, Bo, Yu, Xianjun, Shi, Si

“…The treatment modalities for pancreatic ductal adenocarcinoma (PDAC) are limited and unsatisfactory. Although many novel drugs targeting the tumor…”
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Diagnostic and prognostic value of carcinoembryonic antigen in pancreatic cancer: a systematic review and meta-analysis by Meng, Qingcai, Shi, Si, Liang, Chen, Liang, Dingkong, Xu, Wenyan, Ji, Shunrong, Zhang, Bo, Ni, Quanxing, Xu, Jin, Yu, Xianjun

“…Carcinoembryonic antigen (CEA) is one of the most widely used tumor markers and is increased in 30%-60% of patients with pancreatic cancer. Although…”
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ARID3A enhances chemoresistance of pancreatic cancer via inhibiting PTEN-induced ferroptosis by Mao, Xiaoqi, Xu, Jin, Xiao, Mingming, Liang, Chen, Hua, Jie, Liu, Jiang, Wang, Wei, Yu, Xianjun, Meng, Qingcai, Shi, Si

“…Currently, chemotherapy remains occupying a pivotal place in the treatment of pancreatic ductal adenocarcinoma (PDAC). Nonetheless, the emergence of drug…”
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Comprehensive analysis of the prognosis and immune infiltration landscape of RNA methylation-related subtypes in pancreatic cancer by Lu, Siyuan, Hua, Jie, Liu, Jiang, Wei, Miaoyan, Liang, Chen, Meng, Qingcai, Zhang, Bo, Yu, Xianjun, Wang, Wei, Xu, Jin

“…RNA methylation refers to a form of methyl modification in RNA that modulates various epigenetic alterations. Mounting studies have focused on its potential…”
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