Search Results - "Meng, Michelle"

A Highly Sensitive and Robust Method for Genome-wide 5hmC Profiling of Rare Cell Populations by Han, Dali, Lu, Xingyu, Shih, Alan H., Nie, Ji, You, Qiancheng, Xu, Meng Michelle, Melnick, Ari M., Levine, Ross L., He, Chuan

“…We present a highly sensitive and selective chemical labeling and capture approach for genome-wide profiling of 5-hydroxylmethylcytosine (5hmC) using DNA…”
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Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance by Liu, Yi, Liang, Guanghao, Xu, Hongjiao, Dong, Wenxin, Dong, Ze, Qiu, Zhiwei, Zhang, Zihao, Li, Fangle, Huang, Yue, Li, Yilin, Wu, Jun, Yin, Shenyi, Zhang, Yawei, Guo, Peijin, Liu, Jun, Xi, Jianzhong Jeff, Jiang, Peng, Han, Dali, Yang, Cai-Guang, Xu, Meng Michelle

“…The ever-increasing understanding of the complexity of factors and regulatory layers that contribute to immune evasion facilitates the development of…”
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Digging deeper into pain: an ethological behavior assay correlating well-being in mice with human pain experience by Pattison, Luke A, Cloake, Alexander, Chakrabarti, Sampurna, Hilton, Helen, Rickman, Rebecca H, Higham, James P, Meng, Michelle Y, Paine, Luke W, Dannawi, Maya, Qiu, Lanhui, Ritoux, Anne, Bulmer, David C, Callejo, Gerard, Smith, Ewan St John

“…The pressing need for safer, more efficacious analgesics is felt worldwide. Preclinical tests in animal models of painful conditions represent one of the…”
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Super-enhancers for RUNX3 are required for cell proliferation in EBV-infected B cell lines by Hosoi, Hiroki, Niibori-Nambu, Akiko, Nah, Giselle Sek Suan, Bahirvani, Avinash Govind, Mok, Michelle Meng Huang, Sanda, Takaomi, Kumar, Alan Prem, Tenen, Daniel G., Ito, Yoshiaki, Sonoki, Takashi, Osato, Motomi

“…•Pharmacological inhibition on seR3s suppresses EBV-positive B cell proliferation.•CRISPR/Cas9-medicated excision of seR3s reduces propagation of the…”
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YTHDF3 modulates hematopoietic stem cells by recognizing RNA m6A modification on Ccnd1 by Zhang, Xiaofei, Cong, Tingting, Wei, Lei, Zhong, Bixi, Wang, Xiaowo, Sun, Jin, Wang, Shuxia, Xu, Meng Michelle, Zhu, Ping, Jiang, Hong, Wang, Jianwei

“…Hematopoietic stem cells (HSCs) build up the blood system throughout lifespan. N6-methyladenosine (m6A), the most prevalent RNA modification, modulates gene…”
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Modulating macrophage polarization for the enhancement of fracture healing, a systematic review by Chow, Simon Kwoon-Ho, Wong, Carissa Hing-Wai, Cui, Can, Li, Michelle Meng-Chen, Wong, Ronald Man Yeung, Cheung, Wing-Hoi

“…All fracture repairs start with the innate immune system with the inflammatory response known as the inflammatory stage guided and driven by the secretion of…”
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Rap1 regulates hematopoietic stem cell survival and affects oncogenesis and response to chemotherapy by Khattar, Ekta, Maung, Kyaw Ze Ya, Chew, Chen Li, Ghosh, Arkasubhra, Mok, Michelle Meng Huang, Lee, Pei, Zhang, Jun, Chor, Wei Hong Jeff, Cildir, Gökhan, Wang, Chelsia Qiuxia, Mohd-Ismail, Nur Khairiah, Chin, Desmond Wai Loon, Lee, Soo Chin, Yang, Henry, Shin, Yong-Jae, Nam, Do-Hyun, Chen, Liming, Kumar, Alan Prem, Deng, Lih Wen, Ikawa, Masahito, Gunaratne, Jayantha, Osato, Motomi, Tergaonkar, Vinay

“…Increased levels and non-telomeric roles have been reported for shelterin proteins, including RAP1 in cancers. Herein using Rap1 null mice, we provide the…”
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The Role of Adaptive Immunity in the Efficacy of Targeted Cancer Therapies by Xu, Meng Michelle, Pu, Yang, Zhang, Yuan, Fu, Yang-Xin

“…Accumulating evidence indicates that the efficacy of tumor-targeted therapies relies on the host immune response, including targeted small-molecule and…”
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Mettl3-m6A-Creb1 forms an intrinsic regulatory axis in maintaining iNKT cell pool and functional differentiation by You, Menghao, Liu, Jingjing, Li, Jie, Ji, Ce, Ni, Haochen, Guo, Wenhui, Zhang, Jiarui, Jia, Weiwei, Wang, Zhao, Zhang, Yajiao, Yao, Yingpeng, Yu, Guotao, Ji, Huanyu, Wang, Xiaohu, Han, Dali, Du, Xuguang, Xu, Meng Michelle, Yu, Shuyang

“…N6-methyladenosine (m6A) methyltransferase Mettl3 is involved in conventional T cell immunity; however, its role in innate immune cells remains largely…”
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Naturally occurring combinations of receptors from single cell transcriptomics in endothelial cells by Domanskyi, Sergii, Hakansson, Alex, Meng, Michelle, Pham, Benjamin K., Graff Zivin, Joshua S., Piermarocchi, Carlo, Paternostro, Giovanni, Ferrara, Napoleone

“…VEGF inhibitor drugs are part of standard care in oncology and ophthalmology, but not all patients respond to them. Combinations of drugs are likely to be…”
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RUNX1-ETO (RUNX1-RUNX1T1) induces myeloid leukemia in mice in an age-dependent manner by Abdallah, Mohamed Gaber, Niibori-Nambu, Akiko, Morii, Mariko, Yokomizo, Takako, Yokomizo, Tomomasa, Ideue, Takako, Kubota, Sho, Teoh, Vania Swee Imm, Mok, Michelle Meng Huang, Wang, Chelsia Qiuxia, Omar, Abdellah Ali, Tokunaga, Kenji, Iwanaga, Eisaku, Matsuoka, Masao, Asou, Norio, Nakagata, Naomi, Araki, Kimi, AboElenin, Mabrouk, Madboly, Sayed Hamada, Sashida, Goro, Osato, Motomi

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N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription by Liu, Jun, Dou, Xiaoyang, Chen, Chuanyuan, Chen, Chuan, Liu, Chang, Xu, Meng Michelle, Zhao, Siqi, Shen, Bin, Gao, Yawei, Han, Dali, He, Chuan

“…A new layer of transcriptional controlN6-methyladenosine (m6A) is the most abundant messenger RNA modification in almost all eukaryotes. Liu et al. now show…”
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HR-pQCT for the Evaluation of Muscle Quality and Intramuscular Fat Infiltration in Ageing Skeletal Muscle by Chow, Simon Kwoon-Ho, van Mourik, Marloes, Hung, Vivian Wing-Yin, Zhang, Ning, Li, Michelle Meng-Chen, Wong, Ronald Man-Yeung, Leung, Kwok-Sui, Cheung, Wing-Hoi

“…Myosteatosis is the infiltration of fat in skeletal muscle during the onset of sarcopenia. The quantification of intramuscular adipose tissue (IMAT) can be a…”
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Oncofetal protein IGF2BP1 regulates IQGAP3 expression to maintain stem cell potential in cancer by Myint, Khine, Chuang, Linda Shyue Huey, Teh, Yu Xuan, Mawan, Nur Astiana, Shi, Edward Jizhong, Mok, Michelle Meng Huang, Nuttonmanit, Napat, Matsuo, Junichi, Li, Ying, Yang, Henry, Okabe, Atsushi, Kaneda, Atsushi, Osato, Motomi, So, Jimmy Bok-Yan, Yong, Wei Peng, Tan, Patrick, Yeoh, Khay Guan, Ito, Yoshiaki

“…We reported earlier that IQGAP3 is an important stem cell factor in rapidly proliferating isthmus stem cells in the stomach and that IQGAP3 expression is…”
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Tocilizumab Induces IL-10-Mediated Immune Tolerance in Invasive Candidiasis by Tan, Zhaohong, Mok, Michelle Meng Huang, Mar Soe, Win, Thamboo, Thomas Paulraj, Goh, Jessamine Geraldine, Sam, Qi Hui, Osato, Motomi, Ravikumar, Sharada, Chai, Louis Yi Ann

“…The existence of a hyperinflammatory state has been observed in patients with invasive fungal infections (IFI). It is being postulated whether morbidity from…”
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Side-to-side elbow range of movement variability in an ulnar neurodynamic test sequence variant in asymptomatic people by Tong, Michelle Meng Yim, Liu, Vincent Cheng-Hsin, Hall, Toby

“…Background: Range of motion (ROM) asymmetry between sides is one indicator of a positive neurodynamic test, but this has been less well studied for the ulnar…”
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3D-printed cobalt-chromium porous metal implants showed enhanced bone-implant interface and bone in-growth in a rabbit epiphyseal bone defect model by Chim, Yu Ning, Chow, Simon Kwoon Ho, Mak, Sze Yi, Li, Michelle Meng Chen, Yung, Bob Ching Hang, Yau, Edmond Wing Fung, Chui, Elvis Chun Sing

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RNA Modification in the Immune System by Han, Dali, Xu, Meng Michelle

“…Characterization of RNA modifications has identified their distribution features and molecular functions. Dynamic changes in RNA modification on various forms…”
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Preleukemic and second-hit mutational events in an acute myeloid leukemia patient with a novel germline RUNX1 mutation by Ng, Isaac Ks, Lee, Joanne, Ng, Christopher, Kosmo, Bustamin, Chiu, Lily, Seah, Elaine, Mok, Michelle Meng Huang, Tan, Karen, Osato, Motomi, Chng, Wee-Joo, Yan, Benedict, Tan, Lip Kun

“…Germline mutations in the transcription factor give rise to a rare autosomal dominant genetic condition classified under the entity: Familial Platelet…”
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Filming a live cell by scanning electrochemical microscopy: label-free imaging of the dynamic morphology in real time by Zhang, Michelle Meng-Ni, Long, Yi-Tao, Ding, Zhifeng

“…The morphology of a live cell reflects the organization of the cytoskeleton and the healthy status of the cell. We established a label-free platform for…”
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