Search Results - "Meng, Juanxia"

ROS-mediated iron overload injures the hematopoiesis of bone marrow by damaging hematopoietic stem/progenitor cells in mice by Chai, Xiao, Li, Deguan, Cao, Xiaoli, Zhang, Yuchen, Mu, Juan, Lu, Wenyi, Xiao, Xia, Li, Chengcheng, Meng, Juanxia, Chen, Jie, Li, Qing, Wang, Jishi, Meng, Aimin, Zhao, Mingfeng

“…Iron overload, caused by hereditary hemochromatosis or repeated blood transfusions in some diseases, such as beta thalassemia, bone marrow failure and…”
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Anti-CD19 CAR-T as a feasible and safe treatment against central nervous system leukemia after intrathecal chemotherapy in adults with relapsed or refractory B-ALL by He, Xiaoyuan, Xiao, Xia, Li, Qing, Jiang, Yanyu, Cao, Yaqing, Sun, Rui, Jin, Xin, Yuan, Ting, Meng, Juanxia, Ma, Li, Lu, Wenyi, Lyu, Cuicui, Liu, Kaiqi, Zhao, Mingfeng

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Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice by Jin, Xin, He, Xiaoyuan, Cao, Xiaoli, Xu, Ping, Xing, Yi, Sui, Songnan, Wang, Luqiao, Meng, Juanxia, Lu, Wenyi, Cui, Rui, Ni, Hongyan, Zhao, Mingfeng

“…There is increasing clinical evidence to suggest a suppressive effect on hematopoiesis in myelodysplastic syndrome patients with iron overload. However, how…”
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CAR-T cells dual-target CD123 and NKG2DLs to eradicate AML cells and selectively target immunosuppressive cells by Jin, Xin, Xie, Danni, Sun, Rui, Lu, Wenyi, Xiao, Xia, Yu, Yibing, Meng, Juanxia, Zhao, Mingfeng

“…Chimeric antigen receptor (CAR)-T cells have not made significant progress in the treatment of acute myeloid leukemia (AML) in earlyclinical studies. This lack…”
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CD19 CAR-T cell treatment conferred sustained remission in B-ALL patients with minimal residual disease by Lu, Wenyi, Wei, Yunxiong, Cao, Yaqing, Xiao, Xia, Li, Qing, Lyu, Hairong, Jiang, Yili, Zhang, Huan, Li, Xin, Jiang, Yanyu, Meng, Juanxia, Yuan, Ting, Zhu, Haibo, He, Xiaoyuan, Jin, Xin, Sun, Rui, Sui, Tao, Liu, Kaiqi, Zhao, Mingfeng

“…The persistence or recurrence of minimal residual disease (MRD) after chemotherapy predicts relapse of B-cell acute lymphoblastic leukemia (B-ALL)…”
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Effects of iron overload on the bone marrow microenvironment in mice by Zhang, Yuchen, Zhai, Wenjing, Zhao, Mingfeng, Li, Deguan, Chai, Xiao, Cao, Xiaoli, Meng, Juanxia, Chen, Jie, Xiao, Xia, Li, Qing, Mu, Juan, Shen, Jichun, Meng, Aimin

“…Using a mouse model, Iron Overload (IO) induced bone marrow microenvironment injury was investigated, focusing on the involvement of reactive oxygen species…”
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HLA-matched and HLA-haploidentical allogeneic CD19-directed chimeric antigen receptor T-cell infusions are feasible in relapsed or refractory B-cell acute lymphoblastic leukemia before hematopoietic stem cell transplantation by Jin, Xin, Cao, Yaqing, Wang, Luqiao, Sun, Rui, Cheng, Lin, He, Xiaoyuan, Xiao, Xia, Jiang, Yili, Li, Qing, Zhang, Huan, Lu, Wenyi, Lyu, Cuicui, Jiang, Yanyu, Meng, Juanxia, Zhao, Mingfeng

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TTMV::RARA-positive acute promyelocytic leukemia with marrow necrosis and central nervous system involvement at disease recurrence by Wang, Zhao, Chen, Jiaqi, Meng, Juanxia, Zhao, Mingfeng, Liu, Hongxing, Xiao, Xia

“…Since the identification of the TTMV::RARA fusion in pediatric cases resembling acute promyelocytic leukemia (APL) by Astolfi et al. in 2021, several similar…”
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Low-dose administration of prednisone has a good effect on the treatment of prolonged hematologic toxicity post-CD19 CAR-T cell therapy by Wang, Jiaxi, Zhang, Meng, Lyu, Hairong, Guo, Ruiting, Xiao, Xia, Bai, Xue, Pu, Yedi, Meng, Juanxia, Li, Qing, Yuan, Ting, Lu, Wenyi, Zhao, Mingfeng

“…Hematologic toxicity (HT) is a joint adverse event after CAR-T cells infusion. Some patients experience prolonged hematologic toxicity (PHT), which is…”
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A Prospective Trial Comparing Haploidentical Donor Transplantation With Cord Blood Versus HLA-Matched Sibling Donor Transplantation for Hematologic Malignancy Patients by Lu, Wenyi, Jin, Xin, Lyu, Hairong, Bai, Xue, Zhu, Haibo, Li, Xin, Xiao, Xia, Meng, Juanxia, Yuan, Ting, Li, Qing, Mu, Juan, Lyu, Cuicui, Jiang, Yili, Wei, Yunxiong, Xiong, Xia, Zhang, Meng, Zhao, Mingfeng

“…Although haploidentical donor (HID) hematopoietic stem cell transplantation (HSCT) has achieved similar survival to HLA-identical sibling donor (ISD)…”
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Overexpression of Both ERG11 and ABC2 Genes Might Be Responsible for Itraconazole Resistance in Clinical Isolates of Candida krusei by He, Xiaoyuan, Zhao, Mingfeng, Chen, Jinyan, Wu, Rimao, Zhang, Jianlei, Cui, Rui, Jiang, Yanyu, Chen, Jie, Cao, Xiaoli, Xing, Yi, Zhang, Yuchen, Meng, Juanxia, Deng, Qi, Sui, Tao

“…To study the main molecular mechanisms responsible for itraconazole resistance in clinical isolates of Candida krusei. The 14α-demethylases encoded by ERG11…”
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Efficacy and safety of humanized anti‐CD19‐CAR‐T therapy following intensive lymphodepleting chemotherapy for refractory/relapsed B acute lymphoblastic leukaemia by Wang, Jia, Mou, Nan, Yang, Zhenxing, Li, Qing, Jiang, Yanyu, Meng, Juanxia, Liu, Xuxiang, Deng, Qi

“…Summary We studied the efficacy and safety of humanized CAR‐T therapy following intensive chemotherapy for refractory/relapsed (R/R) acute lymphoblastic…”
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Plasma Exchange Can Be an Alternative Therapeutic Modality for Severe Cytokine Release Syndrome after Chimeric Antigen Receptor-T Cell Infusion: A Case Report by Xiao, Xia, He, Xiaoyuan, Li, Qing, Zhang, Huan, Meng, Juanxia, Jiang, Yanyu, Deng, Qi, Zhao, Mingfeng

“…Tumor immunotherapy with chimeric antigen receptor-T cells (CAR-T) is a promising new treatment for B-cell malignancies and has produced exciting results…”
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Multi-centers experience using therapeutic plasma exchange for corticosteroid/tocilizumab-refractory cytokine release syndrome following CAR-T therapy by Pu, Yedi, Zhao, Yifan, Qi, Yuekun, Liu, Yang, Zhang, Meng, Xiao, Xia, Lyu, Hairong, Meng, Juanxia, Zhu, Haibo, Xu, Kailin, Han, Weidong, Zhao, Mingfeng

“…•CRS is the most prevalent complication of CAR-T therapy.•Therapeutic plasma exchange can be a valuable and safe treatment for severe CRS caused by CAR-T cell…”
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Prophylactic donor-derived CD19 CAR-T cell infusion for preventing relapse in high-risk B-ALL after allogeneic hematopoietic stem cell transplantation by Lu, Wenyi, Lyu, Hairong, Xiao, Xia, Bai, Xue, Zhang, Meng, Wang, Jiaxi, Pu, Yedi, Meng, Juanxia, Zhang, Xiaomei, Zhu, Haibo, Yuan, Ting, Wang, Bing, Jin, Xin, Cao, Xinping, Wang, Zhao, Xie, Tianle, Meng, Haotian, Stepanov, Alexey V., Gabibov, Alexander G., An, Yuxin, Sun, Rui, Zhang, Yu, Maschan, Mikhail A., Zhu, Zunmin, Zhang, Hongkai, Zhao, Mingfeng

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Anti-CD19-CAR T-Cell from Patients Relapsed after Allo-HSCT with a Low Level of Donor Chimerism Restored to Complete Donor Chimerism: Successful Cases and Analysis by Li, Qing, Mu, Juan, Yang, Zhen-xing, Mou, Nan, Wang, Jia, Yuan, Ji-jun, Jiang, Yanyu, Juanxia, Meng, Deng, Qi

“…Purpose: To study the efficacy of anti-CD19-CAR T-cell therapy and the changes of donor chimerism in CAR-T cells in vitro culture for patients who relapsed…”
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Free iron catalyzes oxidative damage to hematopoietic cells/mesenchymal stem cells in vitro and suppresses hematopoiesis in iron overload patients by Lu, Wenyi, Zhao, Mingfeng, Rajbhandary, Sajin, Xie, Fang, Chai, Xiao, Mu, Juan, Meng, Juanxia, Liu, Yongjun, Jiang, Yan, Xu, Xinnv, Meng, Aimin

“…Objectives Transfusional iron overload is of major concern in hematological disease. Iron‐overload‐related dyserythropoiesis and reactive oxygen species…”
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Prophylactic or Preemptive Donor-Derived CD19 CAR-T Cell Infusion for Preventing Relapse in High-Risk B-ALL after Allogeneic Hematopoietic Stem Cell Transplantation by Lu, Wenyi, Zhang, Meng, Lv, Hairong, Xiao, Xia, Bai, Xue, Wang, Jiaxi, Pu, Yedi, Meng, Juanxia, Zhang, Xiaomei, Zhu, Haibo, Yuan, Ting, Wang, Bing, Jin, Xin, Cao, Xinping, Wang, Zhao, Xie, Tianle, Meng, Haotian, Stepanov, Alexey, Gabibov, Alexander G., An, Yuxin, Sun, Rui, Zhang, Yu, Maschan, Mikhail A., Zhu, Zunmin, Zhang, Hongkai, Zhao, Mingfeng

“…Introduction: Relapse remains a significant challenge in the management of high-risk B-cell acute lymphoblastic leukemia (B-ALL) patients undergoing allogeneic…”
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A Phase I Clinical Trial of CLL-1 CAR-T Cells for the Treatment of Relapsed/Refractory Acute Myeloid Leukemia in Adults by Zhang, Xiaomei, Lv, Hairong, Xiao, Xia, Bai, Xue, Liu, Pengjiang, Pu, Yedi, Meng, Juanxia, Zhu, Haibo, Wang, Zhao, Zhang, Huan, Zhang, Yu, Lv, Cuicui, Ma, Li, Yuan, Ting, Zhang, Meng, Sun, Rui, Zhao, Yifan, Cao, Xinping, Guo, Ruiting, Zhang, Yi, Guo, Shujing, Liu, Jile, Zhao, Mingfeng

“…Background: Relapsed/refractory acute myeloid leukemia (r/r AML) has a poor prognosis, and most patients fail standard chemotherapy and hematopoietic stem cell…”
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Successful treatment of second-time CAR-T 19 therapy after failure of first-time CAR-T 19 and ibrutinib therapy in relapsed mantle cell lymphoma by Mu, Juan, Liu, Meijing, Wang, Jia, Meng, Juanxia, Zhang, Rui, Jiang, Yanyu, Deng, Qi

“…A patient with relapsed mantle cell lymphoma (MCL) showed stable disease after receiving ibrutinib therapy as a salvage therapy, after the failure of his first…”
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