Search Results - "Meng, Jingshu"

Small Extracellular Vesicles: A Novel Avenue for Cancer Management by Gao, Yanan, Qin, You, Wan, Chao, Sun, Yajie, Meng, Jingshu, Huang, Jing, Hu, Yan, Jin, Honglin, Yang, Kunyu

“…Extracellular vesicles are small membrane particles derived from various cell types. EVs are broadly classified as ectosomes or small extracellular vesicles,…”
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Targeting senescence-like fibroblasts radiosensitizes non-small cell lung cancer and reduces radiation-induced pulmonary fibrosis by Meng, Jingshu, Li, Yan, Wan, Chao, Sun, Yajie, Dai, Xiaomeng, Huang, Jing, Hu, Yan, Gao, Yanan, Wu, Bian, Zhang, Zhanjie, Jiang, Ke, Xu, Shuangbing, Lovell, Jonathan F, Hu, Yu, Wu, Gang, Jin, Honglin, Yang, Kunyu

“…Cancer cell radioresistance is the primary cause of the decreased curability of non-small cell lung cancer (NSCLC) observed in patients receiving definitive…”
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FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer by Zhou, Zhiyuan, Zhang, Bin, Deng, Yue, Deng, Suke, Li, Jie, Wei, Wenwen, Wang, Yijun, Wang, Jiacheng, Feng, Zishan, Che, Mengjie, Yang, Xiao, Meng, Jingshu, Li, Yan, Hu, Yan, Sun, Yajie, Wen, Lu, Huang, Fang, Sheng, Yuhan, Wan, Chao, Yang, Kunyu

“…The development of radioresistance seriously hinders the efficacy of radiotherapy in lung cancer. However, the underlying mechanisms by which radioresistance…”
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Stabilization of KPNB1 by deubiquitinase USP7 promotes glioblastoma progression through the YBX1-NLGN3 axis by Li, Jie, Zhang, Bin, Feng, Zishan, An, Dandan, Zhou, Zhiyuan, Wan, Chao, Hu, Yan, Sun, Yajie, Wang, Yijun, Liu, Xixi, Wei, Wenwen, Yang, Xiao, Meng, Jingshu, Che, Mengjie, Sheng, Yuhan, Wu, Bian, Wen, Lu, Huang, Fang, Li, Yan, Yang, Kunyu

“…Glioblastoma (GBM) is the most common malignant tumor of the central nervous system. It is an aggressive tumor characterized by rapid proliferation, diffuse…”
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Diagnosis and Treatment of Synchronous Lymphoma and Digestive System Carcinoma: Report of Four Cases and Literature Review by Meng, Jingshu, Pan, Huaxiong, Li, Xiaoqian, Liu, Tao, Liu, Zijian, Li, Qiuhui, Xiao, Yin, Liu, Xinxiu, Wu, Gang, Zhu, Fang, Zhang, Liling

“…To investigate the diagnosis and treatment of synchronous lymphoma and digestive system carcinoma and review literature. We retrospectively analyzed the…”
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Radiated tumor cell-derived microparticles effectively kill stem-like tumor cells by increasing reactive oxygen species by Hu, Yan, Wan, Chao, Yang, Xiao, Tian, Yu, Deng, Suke, An, Dandan, Wang, Yijun, Wang, Jiacheng, Liao, Zhiyun, Meng, Jingshu, Qin, You, Sun, Yajie, Yang, Kunyu

“…Stem-like tumor cells (SLTCs) are thought to be the cellular entity responsible for clinical recurrence and subsequent metastasis. Inhibiting or killing SLTCs…”
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Targeting the Cascade Amplification of Macrophage Colony-stimulating Factor to Alleviate the Immunosuppressive Effects Following Radiotherapy by Liao, Zhiyun, Wang, Yijun, Yang, Yuxin, Liu, Xixi, Yang, Xiao, Tian, Yu, Deng, Suke, Hu, Yan, Meng, Jingshu, Li, Jie, Deng, Yue, Zhou, Zhiyuan, Wei, Wenwen, Swift, Michelle, Wan, Chao, Sun, Yajie, Yang, Kunyu

“…Radiotherapy (RT) serves as the primary treatment for solid tumors. Its potential to incite an immune response against tumors both locally and distally…”
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USP7 targeting modulates anti-tumor immune response by reprogramming Tumor-associated Macrophages in Lung Cancer by Dai, Xiaomeng, Lu, Lisen, Deng, Suke, Meng, Jingshu, Wan, Chao, Huang, Jing, Sun, Yajie, Hu, Yan, Wu, Bian, Wu, Gang, Lovell, Jonathan F., Jin, Honglin, Yang, Kunyu

“…Background: Tumor associated macrophages (TAMs) have strong plasticity and if reprogrammed, can clear tumor cells and regulate the adaptive immune system for…”
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Irradiated tumor cell-derived microparticles mediate tumor eradication via cell killing and immune reprogramming by Wan, Chao, Sun, Yajie, Tian, Yu, Lu, Lisen, Dai, Xiaomeng, Meng, Jingshu, Huang, Jing, He, Qianyuan, Wu, Bian, Zhang, Zhanjie, Jiang, Ke, Hu, Desheng, Wu, Gang, Lovell, Jonathan F, Jin, Honglin, Yang, Kunyu

“…Radiotherapy (RT) is routinely used in cancer treatment, but expansion of its clinical indications remains challenging. The mechanism underlying the…”
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Identification of Hub Genes and Key Pathways Associated with Two Subtypes of Diffuse Large B-Cell Lymphoma Based on Gene Expression Profiling via Integrated Bioinformatics by Zhang, Liling, Liu, Tao, Zhu, Fang, Li, Xiaoqian, Meng, Jingshu, Liu, Zijian, Wu, Gang

“…There is a significant difference in prognosis between the germinal center B-cell (GCB) and activated B-cell (ABC) subtypes of diffuse large B-cell lymphoma…”
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Ionizing Radiation-Induced Tumor Cell-Derived Microparticles Prevent Lung Metastasis by Remodeling the Pulmonary Immune Microenvironment by Zhai, Danyi, Huang, Jing, Hu, Yan, Wan, Chao, Sun, Yajie, Meng, Jingshu, Zi, Huaduan, Lu, Lisen, He, Qianyuan, Hu, Yu, Jin, Honglin, Yang, Kunyu

“…The majority of cancer-related deaths are attributed to metastasis rather than localized primary tumor progression. However, the factors that regulate the…”
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Targeting CAMKII to reprogram tumor-associated macrophages and inhibit tumor cells for cancer immunotherapy with an injectable hybrid peptide hydrogel by Dai, Xiaomeng, Meng, Jingshu, Deng, Suke, Zhang, Lingling, Wan, Chao, Lu, Lisen, Huang, Jing, Hu, Yan, Zhang, Zhanjie, Li, Yan, Lovell, Jonathan F, Wu, Gang, Yang, Kunyu, Jin, Honglin

“…Simultaneously targeted treatment of tumor cells and their surrounding growth-supporting immune cells is a promising strategy to reshape immunosuppressive…”
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Epidemiologic characteristics of malignant lymphoma in Hubei, China: A single-center 5-year retrospective study by Meng, Jingshu, Chang, Chan, Pan, Huaxiong, Zhu, Fang, Xiao, Yin, Liu, Tao, Nie, Xiu, Wu, Gang, Zhang, Liling

“…Distribution of different malignant lymphoma subtypes varies substantially in different geographic regions, even in different districts in China.In order to…”
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Ferroptosis‐Enhanced Immunotherapy with an Injectable Dextran‐Chitosan Hydrogel for the Treatment of Malignant Ascites in Hepatocellular Carcinoma by Meng, Jingshu, Yang, Xiao, Huang, Jing, Tuo, Zhan, Hu, Yan, Liao, Zhiyun, Tian, Yu, Deng, Suke, Deng, Yue, Zhou, Zhiyuan, Lovell, Jonathan F., Jin, Honglin, Liu, Yang, Yang, Kunyu

“…Malignant ascites in advanced hepatocellular carcinoma (HCC) is a complex clinical problem that lacks effective treatments. Due to the insensitivity of…”
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Deubiquitinase USP7 stabilizes KDM5B and promotes tumor progression and cisplatin resistance in nasopharyngeal carcinoma through the ZBTB16/TOP2A axis by Zhang, Bin, Li, Jie, Wang, Yijun, Liu, Xixi, Yang, Xiao, Liao, Zhiyun, Deng, Suke, Deng, Yue, Zhou, Zhiyuan, Tian, Yu, Wei, Wenwen, Meng, Jingshu, Hu, Yan, Wan, Chao, Zhang, Zhanjie, Huang, Fang, Wen, Lu, Wu, Bian, Sun, Yajie, Li, Yan, Yang, Kunyu

“…Cisplatin-based chemotherapy improves the control of distant metastases in patients with nasopharyngeal carcinoma (NPC); however, around 30% of patients fail…”
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Irradiated engineered tumor cell-derived microparticles remodel the tumor immune microenvironment and enhance antitumor immunity by Hu, Yan, Sun, Yajie, Liao, Zhiyun, An, Dandan, Liu, Xixi, Yang, Xiao, Tian, Yu, Deng, Suke, Meng, Jingshu, Wang, Yijun, Li, Jie, Deng, Yue, Zhou, Zhiyuan, Chen, Qinyan, Ye, Ying, Wei, Wenwen, Wu, Bian, Lovell, Jonathan F, Jin, Honglin, Huang, Fang, Wan, Chao, Yang, Kunyu

“…Radiotherapy (RT), administered to roughly half of all cancer patients, occupies a crucial role in the landscape of cancer treatment. However, expanding the…”
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Tumor cell senescence-induced macrophage CD73 expression is a critical metabolic immune checkpoint in the aging tumor microenvironment by Deng, Yue, Chen, Qinyan, Yang, Xiao, Sun, Yajie, Zhang, Bin, Wei, Wenwen, Deng, Suke, Meng, Jingshu, Hu, Yan, Wang, Yijun, Zhang, Zhanjie, Wen, Lu, Huang, Fang, Wan, Chao, Yang, Kunyu

“…The role of senescent cells in the tumor microenvironment (TME) is usually bilateral, and diverse therapeutic approaches, such as radiotherapy and…”
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Expression of Nischarin negatively correlates with estrogen receptor and alters apoptosis, migration and invasion in human breast cancer by Chang, Chan, Wei, Wujie, Han, Dan, Meng, Jingshu, Zhu, Fang, Xiao, Yin, Wu, Gang, Shi, Xing, Zhang, Liling

“…Nischarin, a novel integrin binding protein, has been demonstrated its negative effects on cell migration and invasion. However, the biological role of…”
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Comprehensive Bioinformatics Analysis of Gasdermin Family of Glioma by Zi, Huaduan, Tuo, Zhan, He, Qianyuan, Meng, Jingshu, Hu, Yan, Li, Yan, Yang, Kunyu

“…Pyroptosis is a programmed cell death mediated by gasdermins (GSDMs). The prognostic value of pyroptosis-related genes in different tumor types has been…”
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Downregulation of ABI2 expression by EBV-miR-BART13-3p induces epithelial-mesenchymal transition of nasopharyngeal carcinoma cells through upregulation of c-JUN/SLUG signaling by Huang, Jing, Qin, You, Yang, Chensu, Wan, Chao, Dai, Xiaomeng, Sun, Yajie, Meng, Jingshu, Lu, Yanwei, Li, Yan, Zhang, Zhanjie, Wu, Bian, Xu, Shuangbing, Jin, Honglin, Yang, Kunyu

“…Existing evidence has shown that circulating Epstein-Barr virus (EBV)-miR-BART13-3p is highly expressed in plasma of nasopharyngeal carcinoma (NPC) patients,…”
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