Search Results - "Meng, Erhong"

ALDH1A1 maintains ovarian cancer stem cell-like properties by altered regulation of cell cycle checkpoint and DNA repair network signaling by Meng, Erhong, Mitra, Aparna, Tripathi, Kaushlendra, Finan, Michael A, Scalici, Jennifer, McClellan, Steve, Madeira da Silva, Luciana, Reed, Eddie, Shevde, Lalita A, Palle, Komaraiah, Rocconi, Rodney P

“…Aldehyde dehydrogenase (ALDH) expressing cells have been characterized as possessing stem cell-like properties. We evaluated ALDH+ ovarian cancer stem…”
Get full text

Dramatic response to local radiotherapy in a refractory metastatic mediastinal yolk sac tumor patient harboring a germline BRCA2 frameshift mutation: a case report by Cheng, Xi, Yu, Haiming, Li, Jinying, Han, Xiaona, Meng, Erhong, Zhou, Houqing, Wang, Dongliang, Niu, Beifang, Zhang, Xiaotao

“…Mediastinal yolk sac tumors (YSTs) are highly aggressive germ cell tumors with an extremely poor prognosis. Radiotherapy plays an important role in the…”
Get full text

Case Report: Triple Primary Malignant Tumors of the Esophagus, Stomach, and Colon in a Patient With Genetic Analysis by Zhan, Xiaoli, He, Lingzhe, Song, Kai, Cao, Shuliang, Meng, Erhong, Wang, Yuedong

“…The incidence of multiple primary malignant tumors (MPMTs) has increased greatly with the progress of tumor diagnosis and therapy technology. However, triple…”
Get full text

Comprehensive analysis of immune-related prognostic genes in the tumour microenvironment of hepatocellular carcinoma by Gao, Weike, Li, Luan, Han, Xinyin, Liu, Siyao, Li, Chengzhen, Yu, Guanying, Zhang, Lei, Zhang, Dongsheng, Liu, Caiyun, Meng, Erhong, Hong, Shuai, Wang, Dongliang, Guo, Peiming, Shi, Guangjun

“…The mortality rate of hepatocellular carcinoma (HCC) remains high worldwide despite surgery and chemotherapy. Immunotherapy is a promising treatment for the…”
Get full text

Identification of a Novel Immune-Related CpG Methylation Signature to Predict Prognosis in Stage II/III Colorectal Cancer by Chen, Feng, Pei, Lijuan, Liu, Siyao, Lin, Yan, Han, Xinyin, Meng, Erhong, Wang, Xintong, Hong, Shuai, Wang, Dongliang, Liu, Feide, Fei, Yang, Wang, Guangda

“…With the increasing incidence of colorectal cancer (CRC) and continued difficulty in treating it using immunotherapy, there is an urgent need to identify an…”
Get full text

Complete and durable response to crizotinib in a patient with malignant pleural mesothelioma harboring CD74-ROS1 fusion by Xie, Xuehua, You, Mengxing, Meng, Erhong, Wang, Shunyou, Niu, Beifang, Huang, Weiming

“…Malignant pleural mesothelioma (MPM) is a rare and deadly malignancy with an extremely poor prognosis. The median overall survival (OS) of this disease is…”
Get full text

Long-term response to camrelizumab in a pretreated metastatic mixed testicular germ-cell tumor patient with co-mutations in DNA damage-repair genes by Zhang, Hui, Jiang, Da, Meng, Erhong, Zhao, Meng, Niu, Beifang

“…Little information is available regarding the therapeutic efficacy of immune checkpoint inhibitors and the prediction of DNA damage-repair (DDR) genes in mixed…”
Get full text

Retraction: Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer by Meng, Erhong, Shevde, Lalita A, Samant, Rajeev S

Get full text

CD44+/CD24− ovarian cancer cells demonstrate cancer stem cell properties and correlate to survival by Meng, Erhong, Long, Beverely, Sullivan, Paula, McClellan, Steve, Finan, Michael A., Reed, Eddie, Shevde, Lalita, Rocconi, Rodney P.

“…Cancer cells with the surface marker profile CD44+/CD24− have previously been described to possess cancer stem cell-like properties. This manuscript evaluates…”
Get full text

Genetic landscape of 43 patients with dMMR gastric cancer and its clinical implications by Wang, Dongliang, Hu, Nana, Xu, Quan, Meng, Erhong, Li, Zhongwu, Shen, Lin

“…Abstract only e16501 Background: The FDA has approved immune checkpoint inhibitors for dMMR/MSI-H patients with solid tumors, but the efficacy varies greatly,…”
Get full text

Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer by Meng, Erhong, Shevde, Lalita A, Samant, Rajeev S

“…DNAJB6 also known as mammalian relative of DnaJ (MRJ) encodes a highly conserved member of the DnaJ/Hsp40 family of co-chaperone proteins that function with…”
Get full text

Long-term response to sintilimab, bevacizumab and chemotherapy in heavily pretreated microsatellite stable colon cancer by Cui, Zhi, Wang, Qi, Deng, Muhong, Meng, Erhong, Liu, Sheng, Niu, Beifang, Han, Quanli

“…Most advanced colorectal cancer patients with proficient DNA mismatch repair or microsatellite stability (MSS) are insensitive to immune checkpoint inhibitor…”
Get full text

Abstract 5193: Case report: Long-term response to Camrelizumab in a pretreated metastatic mixed testicular germ cell tumor patient by Zhang, Hui, Jiang, Da, Meng, Erhong, Song, Wenya, Zhang, Xue

“…Abstract Introduction: To date, very limited information is available about the efficacy of immune checkpoint inhibitor (ICI) therapy in mixed testicular germ…”
Get full text

Case report: identification of ERC1-RET fusion in a patient with pancreatic ductal adenocarcinoma by Ma, Jia, Wang, Baosheng, Meng, Erhong, Meng, Xiangpeng

“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy. Currently, treatment strategies for PDAC are limited because its molecular characteristics…”
Get full text

Identification of a novel heterozygous germline RAD52 missense mutation in a patient with gallbladder carcinoma: A case report by Zhao, Wenhu, Dai, Yongjiu, Yue, Lei, Gu, Jian, Meng, Erhong, Wang, Dongliang, Liu, Siyao, Han, Xinyin, Wang, Xintong, Li, Guojun, Dai, Xinzheng

“…Gallbladder carcinoma is a malignant biliary tract tumor which is characterized by poor prognosis. Recent advances in genomic medicine have identified a few…”
Get full text

Abstract 5190: Case report: long-term response to combination of Sintilimab, Bevacizumab and chemotherapy in a heavily pretreated refractory colon cancer patient with microsatellite stability by Cui, Zhi, Wang, Qi, Deng, Muhong, Meng, Erhong, Liu, Sheng, Han, Quanli

“…Abstract Background: Unlike patients with advanced colorectal cancer (CRC) with deficient DNA mismatch repair or microsatellite instability-high (dMMR/MSI-H)…”
Get full text

Hedgehog signaling pathway regulates the growth of ovarian cancer spheroid forming cells by Ray, Anasuya, Meng, Erhong, Reed, Eddie, Shevde, Lalita A, Rocconi, Rodney P

“…The hedgehog (Hh) pathway has been shown to be activated in numerous malignancies as well as in cancer stem cells. We sought to determine the importance of the…”
Get more information

Homozygous deletion of the HLA-B gene as an acquired-resistance mechanism to nivolumab in a patient with lung adenocarcinoma: a case report by Zhang, He, Dong, Weiwei, Zhao, Huixia, Zeng, Zhiyan, Zhang, Fengyun, Hu, Yanyan, Li, Qiuwen, Chen, Jing, Meng, Erhong, Xiao, Wenhua

“…Immune checkpoint inhibitors (ICIs) have greatly improved the treatment of advanced non-small-cell lung cancer, including lung adenocarcinoma (LUAD). Patients…”
Get full text

Abstract 3631: A novel combination of Hedgehog inhibitors with carboplatin exhibits synergy in ovarian cancer treatment by altered regulation of DNA repair networks by Spencer, Sebastian M., Tripathi, Kaushlendra, Meng, Erhong, Scalici, Jennifer, Rocconi, Rodney P., Palle, Komaraiah

“…Abstract Ovarian cancer (OVCA) is the deadliest of all the reproductive cancers, affecting over 22,000 lives of women annually in the USA alone. In spite of…”
Get full text

The Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human Cancer by Meng, Erhong, Hanna, Ann, Samant, Rajeev S, Shevde, Lalita A

“…Defined cellular mechanisms have evolved that recognize and repair DNA to protect the integrity of its structure and sequence when encountering assaults from…”
Get full text