Search Results - "Menezes, Ramon R.P.P.B."
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Quantum computational investigations and molecular docking studies on amentoflavone
Published in Heliyon (01-01-2021)“…Chagas disease is a neglected tropical disease caused by the protozoan parasite Trypanosoma cruzi, with approximately 6–7 million people infected worldwide,…”
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Trypanocidal Mechanism of Action and in silico Studies of p -Coumaric Acid Derivatives
Published in International journal of molecular sciences (25-11-2019)“…species are responsible for chronic and systemic infections in millions of people around the world, compromising life quality, and family and government…”
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Piplartine-Inspired 3,4,5-Trimethoxycinnamates: Trypanocidal, Mechanism of Action, and In Silico Evaluation
Published in Molecules (Basel, Switzerland) (02-06-2023)“…Chagas disease (CD) is one of the main neglected tropical diseases that promote relevant socioeconomic impacts in several countries. The therapeutic options…”
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Antiparasitic effect of (−)-α-bisabolol against Trypanosoma cruzi Y strain forms
Published in Diagnostic microbiology and infectious disease (01-11-2019)“…Chagas disease is caused by Trypanosoma cruzi and affects about 7 million people worldwide. Benznidazole and nifurtimox have low efficacy and high toxicity…”
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Antiproliferative activity on Trypanosoma cruzi (Y strain) of the triterpene 3β,6β,16β-trihidroxilup-20 (29)-ene isolated from Combretum leprosum
Published in Journal of biomolecular structure & dynamics (01-01-2022)“…Chagas disease infects approximately seven million people worldwide. Benznidazole is effective only in the acute phase of the disease, with an average cure…”
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Bothropoides pauloensis venom effects on isolated perfused kidney and cultured renal tubular epithelial cells
Published in Toxicon (Oxford) (15-12-2015)“…Snake envenomation (Bothrops genus) is common in tropical countries and acute kidney injury is one of the complications observed in Bothrops snakebite with…”
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Bothropoides insularis venom cytotoxicity in renal tubular epithelia cells
Published in Toxicon (Oxford) (01-09-2014)“…Bothropoides insularis (jararaca-ilhoa) is a native endemic snake limited to the specific region of Queimada Island, on São Paulo coast. Several local and…”
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Involvement of Nitric Oxide on Bothropoides insularis Venom Biological Effects on Murine Macrophages In Vitro
Published in PloS one (14-03-2016)“…Viperidae venom has several local and systemic effects, such as pain, edema, inflammation, kidney failure and coagulopathy. Additionally, bothropic venom and…”
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Antibacterial and antiparasitic effects of Bothropoides lutzi venom
Published in Natural product communications (01-01-2012)“…The therapeutic potential of toxins has aroused great interest in the scientific community. Microbial resistance is a serious current public health problem, in…”
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