Search Results - "Menezes, Ramon Róseo Paula Pessoa Bezerra de"
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Syndecan-1 in Acute Decompensated Heart Failure – Association With Renal Function and Mortality
Published in Circulation Journal (2015)“…Background:Heart failure (HF) is a leading cause of hospitalization throughout the world, and the mortality rate remains elevated. HF is frequently complicated…”
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Association of serum lipoproteins and inflammatory parameters derived from the blood test with renal function in COVID-19 outpatients
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2023)“…Changes in lipoprotein metabolism are among the main causes of hemodynamic impairment in renal function. COVID-19 is an multisystemic inflammatory disease,…”
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3
Anxiolytic and Anticonvulsant Effects of Fisetin Isolated from Bauhinia pentandra on Adult Zebrafish (Danio rerio)
Published in Chemistry & biodiversity (01-11-2024)“…Anxiety and epilepsy are common worldwide and represent a primary global health concern. Fisetin, a flavonoid isolated from Bauhinia pentandra, has a wide…”
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Correlation of Apolipoprotein a-i with Renal Function in Diabetic Patients
Published in Brazilian Archives of Biology and Technology (2024)“…Abstract Diabetes mellitus (DM) is a major cause of chronic kidney disease (CKD) and changes in lipoprotein. Literature data suggest that cholesterol…”
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Arg-substituted VmCT1 analogs reveals promising candidate for the development of new antichagasic agent
Published in Parasitology (01-12-2020)“…VmCT1 is an antimicrobial peptide (AMP) isolated from the venom of the scorpion Vaejovis mexicanus with antimicrobial, anticancer and antimalarial activities,…”
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The dinoponeratoxin peptides from the giant ant Dinoponera quadriceps display in vitro antitrypanosomal activity
Published in Biological chemistry (26-01-2018)“…The crude venom of the giant ant Dinoponera quadriceps is a cocktail of polypeptides and organic compounds that shows antiparasitic effects against Trypanosoma…”
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Protective Effect of Quercetin on Renal Tubular Cells and the Involvement with the Renin-Angiotensin-Aldosterone Axis
Published in Brazilian Archives of Biology and Technology (01-01-2021)“…Abstract Ischemia-reperfusion (I/R) plays an important role in the process of acute kidney injury (AKI) due to the generation of reactive oxygen species (ROS)…”
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Bothrops leucurus venom induces nephrotoxicity in the isolated perfused kidney and cultured renal tubular epithelia
Published in Toxicon (Oxford) (01-01-2013)“…Bites from snake (Bothrops genus) cause local tissue damage and systemic complications, which include alterations such as hemostatic system and acute renal…”
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Wasp venom peptide as a new antichagasic agent
Published in Toxicon (Oxford) (15-07-2020)“…Chagas disease is caused by Trypanosoma cruzi and affects approximately 10 million people a year worldwide. The only two treatment options, benznidazole and…”
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Chloride substitution on 2-hydroxy-3,4,6-trimethoxyphenylchalcones improves in vitro selectivity on Trypanosoma cruzi strain Y
Published in Chemico-biological interactions (01-07-2022)“…Chagas disease is a disease that is emerging in North America and Europe countries. Benznidazole is the main drug available, but it has high toxicity and low…”
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Prescription Drug Overdose, Depression, and Other Mental Disorders in the Context of Kidney Disease
Published in Contributions to nephrology (01-01-2021)“…Clinical Background: Mental disorders, especially depression, are associated with several comorbidities in the kidneys. Depression is the psychiatric disorder…”
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Antichagasic effect of crotalicidin, a cathelicidin-like vipericidin, found in Crotalus durissus terrificus rattlesnake's venom gland
Published in Parasitology (01-07-2018)“…Cathelicidins are antimicrobial peptides produced by humans and animals in response to various pathogenic microbes. Crotalicidin (Ctn), a cathelicidin-related…”
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13
Quantum mechanical, molecular docking, molecular dynamics, ADMET and antiproliferative activity on Trypanosoma cruzi (Y strain) of chalcone ( E )-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3-nitrophenyl)prop-2-en-1-one derived from a natural product
Published in Physical chemistry chemical physics : PCCP (23-02-2022)“…Chagas disease is a leading public health problem. More than 8 million people are affected by the disease, which is endemic in 21 countries in Latin America,…”
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14
Antichagasic effect of hemocyanin derived from antimicrobial peptides of penaeus monodon shrimp
Published in Experimental parasitology (01-08-2020)“…Trypanosoma cruzi, the etiological agent of Chagas disease, is responsible for the infection of millions of people worldwide and it is a public health problem,…”
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Involvement of NADPH-oxidase enzyme in the nephroprotective effect of (−)-α-bisabolol on HK2 cells exposed to ischemia – Reoxygenation
Published in European journal of pharmacology (15-07-2019)“…Acute Kidney Injury (AKI) is associated with high morbidity and mortality. Ischemia and reperfusion (I/R) are events that lead to AKI through hypoxia, reactive…”
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Elongation on aliphatic chain improves selectivity of 2-hydroxy-3,4,6-trimethoxyphenyl chalcone on Trypanosoma cruzi
Published in Future medicinal chemistry (01-01-2024)“…Our objective was to investigate the trypanocidal effect of the chalcone (2 ,4 )-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-5-phenylpenta-2,4-dien-1-one (CPNC)…”
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Antiparasitic effect of Dinoponera quadriceps giant ant venom
Published in Toxicon (Oxford) (15-09-2016)“…Neglected tropical diseases (NTD) are treated with toxic therapy of limited efficacy. Previously, we studied the antimicrobial effect of Dinoponera quadriceps…”
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18
Tyramine exerts hypolipidemic and anti-obesity effects in vivo
Published in Brazilian Journal of Pharmaceutical Sciences (2022)“…Abstract Obesity and dyslipidemia are conditions often associated with cardiovascular risk, inflammation, oxidative stress, and death. Thus, a new approach has…”
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Bothrops erythromelas (Amaral, 1923) venom induces apoptosis on renal tubular epithelial cells
Published in Toxicon (Oxford) (01-08-2016)“…Bothrops erythromelas is responsible for a large number of snakebite incidents in Northeastern Brazil. Previously, we showed the effects of whole…”
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Computational approach towards the design of artemisinin–thymoquinone hybrids against main protease of SARS-COV-2
Published in Future journal of pharmaceutical sciences (06-09-2021)“…Background The sanitary emergency installed in the world, generated by the pandemic of COVID-19, instigates the search for scientific strategies to mitigate…”
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