Search Results - "Menendez, P."

In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells by Martinez-Lage, M., Torres-Ruiz, R., Puig-Serra, P., Moreno-Gaona, P., Martin, M. C., Moya, F. J., Quintana-Bustamante, O., Garcia-Silva, S., Carcaboso, A. M., Petazzi, P., Bueno, C., Mora, J., Peinado, H., Segovia, J. C., Menendez, P., Rodriguez-Perales, S.

“…Fusion oncogenes (FOs) are common in many cancer types and are powerful drivers of tumor development. Because their expression is exclusive to cancer cells and…”
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The MLL recombinome of acute leukemias in 2017 by Meyer, C, Burmeister, T, Gröger, D, Tsaur, G, Fechina, L, Renneville, A, Sutton, R, Venn, N C, Emerenciano, M, Pombo-de-Oliveira, M S, Barbieri Blunck, C, Almeida Lopes, B, Zuna, J, Trka, J, Ballerini, P, Lapillonne, H, De Braekeleer, M, Cazzaniga, G, Corral Abascal, L, van der Velden, V H J, Delabesse, E, Park, T S, Oh, S H, Silva, M L M, Lund-Aho, T, Juvonen, V, Moore, A S, Heidenreich, O, Vormoor, J, Zerkalenkova, E, Olshanskaya, Y, Bueno, C, Menendez, P, Teigler-Schlegel, A, zur Stadt, U, Lentes, J, Göhring, G, Kustanovich, A, Aleinikova, O, Schäfer, B W, Kubetzko, S, Madsen, H O, Gruhn, B, Duarte, X, Gameiro, P, Lippert, E, Bidet, A, Cayuela, J M, Clappier, E, Alonso, C N, Zwaan, C M, van den Heuvel-Eibrink, M M, Izraeli, S, Trakhtenbrot, L, Archer, P, Hancock, J, Möricke, A, Alten, J, Schrappe, M, Stanulla, M, Strehl, S, Attarbaschi, A, Dworzak, M, Haas, O A, Panzer-Grümayer, R, Sedék, L, Szczepański, T, Caye, A, Suarez, L, Cavé, H, Marschalek, R

“…Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant, pediatric, adult and therapy-induced acute leukemias. Here we present the…”
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Assessing the ability of adaptive designs to capture trends in hard coral cover by Thilan, AWLP, Menéndez, P, McGree, JM

“…Coral reefs have become one of the most vulnerable ecosystems worldwide due to rising environmental and anthropogenic pressures. Methods from experimental…”
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The differentiation stage of p53-Rb-deficient bone marrow mesenchymal stem cells imposes the phenotype of in vivo sarcoma development by Rubio, R, Gutierrez-Aranda, I, Sáez-Castillo, A I, Labarga, A, Rosu-Myles, M, Gonzalez-Garcia, S, Toribio, M L, Menendez, P, Rodriguez, R

“…Increasing evidence suggests that mesenchymal stem/stromal cells (MSCs) carrying specific mutations are at the origin of some sarcomas. We have reported that…”
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The KMT2A recombinome of acute leukemias in 2023 by Meyer, C., Larghero, P., Almeida Lopes, B., Burmeister, T., Gröger, D., Sutton, R., Venn, N. C., Cazzaniga, G., Corral Abascal, L., Tsaur, G., Fechina, L., Emerenciano, M., Pombo-de-Oliveira, M. S., Lund-Aho, T., Lundán, T., Montonen, M., Juvonen, V., Zuna, J., Trka, J., Ballerini, P., Lapillonne, H., Van der Velden, V. H. J., Sonneveld, E., Delabesse, E., de Matos, R. R. C., Silva, M. L. M., Bomken, S., Katsibardi, K., Keernik, M., Grardel, N., Mason, J., Price, R., Kim, J., Eckert, C., Lo Nigro, L., Bueno, C., Menendez, P., zur Stadt, U., Gameiro, P., Sedék, L., Szczepański, T., Bidet, A., Marcu, V., Shichrur, K., Izraeli, S., Madsen, H. O., Schäfer, B. W., Kubetzko, S., Kim, R., Clappier, E., Trautmann, H., Brüggemann, M., Archer, P., Hancock, J., Alten, J., Möricke, A., Stanulla, M., Lentes, J., Bergmann, A. K., Strehl, S., Köhrer, S., Nebral, K., Dworzak, M. N., Haas, O. A., Arfeuille, C., Caye-Eude, A., Cavé, H., Marschalek, R.

“…Chromosomal rearrangements of the human KMT2A/MLL gene are associated with de novo as well as therapy-induced infant, pediatric, and adult acute leukemias…”
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The MLL recombinome of acute leukemias in 2013 by Meyer, C, Hofmann, J, Burmeister, T, Gröger, D, Park, T S, Emerenciano, M, Pombo de Oliveira, M, Renneville, A, Villarese, P, Macintyre, E, Cavé, H, Clappier, E, Mass-Malo, K, Zuna, J, Trka, J, De Braekeleer, E, De Braekeleer, M, Oh, S H, Tsaur, G, Fechina, L, van der Velden, V H J, van Dongen, J J M, Delabesse, E, Binato, R, Silva, M L M, Kustanovich, A, Aleinikova, O, Harris, M H, Lund-Aho, T, Juvonen, V, Heidenreich, O, Vormoor, J, Choi, W W L, Jarosova, M, Kolenova, A, Bueno, C, Menendez, P, Wehner, S, Eckert, C, Talmant, P, Tondeur, S, Lippert, E, Launay, E, Henry, C, Ballerini, P, Lapillone, H, Callanan, M B, Cayuela, J M, Herbaux, C, Cazzaniga, G, Kakadiya, P M, Bohlander, S, Ahlmann, M, Choi, J R, Gameiro, P, Lee, D S, Krauter, J, Cornillet-Lefebvre, P, Te Kronnie, G, Schäfer, B W, Kubetzko, S, Alonso, C N, zur Stadt, U, Sutton, R, Venn, N C, Izraeli, S, Trakhtenbrot, L, Madsen, H O, Archer, P, Hancock, J, Cerveira, N, Teixeira, M R, Lo Nigro, L, Möricke, A, Stanulla, M, Schrappe, M, Sedék, L, Szczepański, T, Zwaan, C M, Coenen, E A, van den Heuvel-Eibrink, M M, Strehl, S, Dworzak, M, Panzer-Grümayer, R, Dingermann, T, Klingebiel, T, Marschalek, R

“…Chromosomal rearrangements of the human MLL (mixed lineage leukemia) gene are associated with high-risk infant, pediatric, adult and therapy-induced acute…”
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Alleviating the effect of collinearity in geographically weighted regression by Bárcena, M. J., Menéndez, P., Palacios, M. B., Tusell, F.

“…Geographically weighted regression (GWR) is a popular technique to deal with spatially varying relationships between a response variable and predictors…”
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Biology and therapeutic applications of peroxisome proliferator- activated receptors by Menendez-Gutierrez, Maria P, Roszer, Tamas, Ricote, Mercedes

“…Peroxisome proliferator-activated receptors (PPARs) are ligand dependent transcription factors. The three mammalian PPARs are key regulators of fatty acid and…”
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NG2 antigen is involved in leukemia invasiveness and central nervous system infiltration in MLL-rearranged infant B-ALL by Prieto, C, López-Millán, B, Roca-Ho, H, Stam, R W, Romero-Moya, D, Rodríguez-Baena, F J, Sanjuan-Pla, A, Ayllón, V, Ramírez, M, Bardini, M, De Lorenzo, P, Valsecchi, M G, Stanulla, M, Iglesias, M, Ballerini, P, Carcaboso, Á M, Mora, J, Locatelli, F, Bertaina, A, Padilla, L, Carlos Rodríguez-Manzaneque, Juan, Bueno, C, Menéndez, P

“…Mixed-lineage leukemia (MLL)-rearranged (MLLr) infant B-cell acute lymphoblastic leukemia (iMLLr-B-ALL) has a dismal prognosis and is associated with a…”
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EP06.08: Influence of prenatal risk factors on the prevalence of preleukemic ETV6: RUNX1 lesions in cord blood by Quintanilla, L. Benitez, Fischer, U., Crispi, F., Castro‐Barquero, S., Crovetto, F., Sola, M. Larroya, Youssef, L., Castillo, H., Bueno, C., Borras, R., Borkhardt, A., Vieta, E., Estruch, R., Menendez, P., Gratacos, E.

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Immunophenotypic analysis and quantification of B-1 and B-2 B cells during human fetal hematopoietic development by Bueno, C, van Roon, E H J, Muñoz-López, A, Sanjuan-Pla, A, Juan, M, Navarro, A, Stam, R W, Menendez, P

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Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement by Bueno, C, Montes, R, Catalina, P, Rodríguez, R, Menendez, P

“…Infant acute lymphoblastic leukemia (ALL) involving mixed-lineage leukemia (MLL) fusions has attracted a huge interest in basic and clinical research because…”
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The Notch ligand DLL4 specifically marks human hematoendothelial progenitors and regulates their hematopoietic fate by Ayllón, V, Bueno, C, Ramos-Mejía, V, Navarro-Montero, O, Prieto, C, Real, P J, Romero, T, García-León, M J, Toribio, M L, Bigas, A, Menendez, P

“…Notch signaling is essential for definitive hematopoiesis, but its role in human embryonic hematopoiesis is largely unknown. We show that in hESCs the…”
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Comparative analysis of TIG welding distortions between austenitic and duplex stainless steels by FEM by DEL COZ DIAZ, J. J, MENENDEZ RODRIGUEZ, P, GARCIA NIETO, P. J, CASTRO-FRESNO, D

“…In this study, thermal stress analyses were performed in the tungsten inert gas (TIG) welding process of two different stainless steel specimens in order to…”
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Simultaneous adjustment of bias and coverage probabilities for confidence intervals by Menéndez, P., Fan, Y., Garthwaite, P.H., Sisson, S.A.

“…A new method is proposed for the correction of confidence intervals when the original interval does not have the correct nominal coverage probabilities in the…”
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Reprogramming human B cells into induced pluripotent stem cells and its enhancement by C/EBPα by Bueno, C, Sardina, J L, Di Stefano, B, Romero-Moya, D, Muñoz-López, A, Ariza, L, Chillón, M C, Balanzategui, A, Castaño, J, Herreros, A, Fraga, M F, Fernández, A, Granada, I, Quintana-Bustamante, O, Segovia, J C, Nishimura, K, Ohtaka, M, Nakanishi, M, Graf, T, Menendez, P

“…B cells have been shown to be refractory to reprogramming and B-cell-derived induced pluripotent stem cells (iPSC) have only been generated from murine B cells…”
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Mesenchymal stem cells and their use as cell replacement therapy and disease modelling tool by García‐Castro, J., Trigueros, C., Madrenas, J., Pérez‐Simón, J. A., Rodriguez, R., Menendez, P.

“…•  Introduction •  Mechanisms of immunological tolerance •  MSCs and cell replacement strategies •  Clinical applications based on MSCs immune modulatory…”
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Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia by Pérez-Mato, M, Ramos-Cabrer, P, Sobrino, T, Blanco, M, Ruban, A, Mirelman, D, Menendez, P, Castillo, J, Campos, F

“…Blood glutamate scavenging is a novel and attractive protecting strategy to reduce the excitotoxic effect of extracellular glutamate released during ischemic…”
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GLUT1/GLUT4 balance is a marker of androgen-insensitivity in prostate cancer by Gonzalez-Menendez, P, Hevia, D, Alonso, R, Gonzalez-Pola, I, Mayo, J.C, Sainz, R.M

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Ligand-independent FLT3 activation does not cooperate with MLL-AF4 to immortalize/transform cord blood CD34+ cells by Montes, R, Ayllón, V, Prieto, C, Bursen, A, Prelle, C, Romero-Moya, D, Real, P J, Navarro-Montero, O, Chillón, C, Marschalek, R, Bueno, C, Menendez, P

“…MLL-AF4 fusion is hallmark in high-risk infant pro-B-acute lymphoblastic leukemia (pro-B-ALL). Our limited understanding of MLL-AF4-mediated transformation…”
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