Search Results - "Mendoza, Juan"

Differential induction of interferon stimulated genes between type I and type III interferons is independent of interferon receptor abundance by Pervolaraki, Kalliopi, Rastgou Talemi, Soheil, Albrecht, Dorothee, Bormann, Felix, Bamford, Connor, Mendoza, Juan L, Garcia, K Christopher, McLauchlan, John, Höfer, Thomas, Stanifer, Megan L, Boulant, Steeve

“…It is currently believed that type I and III interferons (IFNs) have redundant functions. However, the preferential distribution of type III IFN receptor on…”
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Insights into Cytokine-Receptor Interactions from Cytokine Engineering by Spangler, Jamie B, Moraga, Ignacio, Mendoza, Juan L, Garcia, K. Christopher

“…Cytokines exert a vast array of immunoregulatory actions critical to human biology and disease. However, the desired immunotherapeutic effects of native…”
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Deconstructing the Peptide-MHC Specificity of T Cell Recognition by Birnbaum, Michael E., Mendoza, Juan L., Sethi, Dhruv K., Dong, Shen, Glanville, Jacob, Dobbins, Jessica, Özkan, Engin, Davis, Mark M., Wucherpfennig, Kai W., Garcia, K. Christopher

“…In order to survey a universe of major histocompatibility complex (MHC)-presented peptide antigens whose numbers greatly exceed the diversity of the T cell…”
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Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences by Mendoza, Juan L., Schmidt, André, Li, Qin, Nuvaga, Emmanuel, Barrett, Tyler, Bridges, Robert J., Feranchak, Andrew P., Brautigam, Chad A., Thomas, Philip J.

“…Misfolding of ΔF508 cystic fibrosis (CF) transmembrane conductance regulator (CFTR) underlies pathology in most CF patients. F508 resides in the first…”
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Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes by Ng, Cherie T., Mendoza, Juan L., Garcia, K. Christopher, Oldstone, Michael B.A.

“…Type I interferon (IFN-I) elicits a complex cascade of events in response to microbial infection. Here, we review recent developments illuminating the large…”
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Colombia's transition to peace is enhancing coca-driven deforestation by Mendoza, Juan P

“…Forests cover 70% of the Colombian territory, which includes part of the Amazon. Recent studies have examined how the country's tree cover dynamics are…”
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Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor by Onabajo, Olusegun O., Banday, A. Rouf, Stanifer, Megan L., Yan, Wusheng, Obajemu, Adeola, Santer, Deanna M., Florez-Vargas, Oscar, Piontkivska, Helen, Vargas, Joselin M., Ring, Timothy J., Kee, Carmon, Doldan, Patricio, Tyrrell, D. Lorne, Mendoza, Juan L., Boulant, Steeve, Prokunina-Olsson, Ludmila

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which causes COVID-19, utilizes angiotensin-converting enzyme 2 (ACE2) for entry into target…”
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Recent and future perspectives on engineering interferons and other cytokines as therapeutics by Aung, Theint, Grubbe, William S., Nusbaum, Rebecca J., Mendoza, Juan L.

“…As crucial mediators and regulators of our immune system, cytokines are involved in a broad range of biological processes and are implicated in various disease…”
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The backfiring effect of auditing on tax compliance by Mendoza, Juan P., Wielhouwer, Jacco L., Kirchler, Erich

“…•We expect a U-shaped association between auditing level and tax evasion.•The analysis employs publicly available country-level data from 2003–2014.•We obtain…”
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Structure of the IFNγ receptor complex guides design of biased agonists by Mendoza, Juan L., Escalante, Nichole K., Jude, Kevin M., Sotolongo Bellon, Junel, Su, Leon, Horton, Tim M., Tsutsumi, Naotaka, Berardinelli, Steven J., Haltiwanger, Robert S., Piehler, Jacob, Engleman, Edgar G., Garcia, K. Christopher

“…The cytokine interferon-γ (IFNγ) is a central coordinator of innate and adaptive immunity, but its highly pleiotropic actions have diminished its prospects for…”
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Antigen Identification for Orphan T Cell Receptors Expressed on Tumor-Infiltrating Lymphocytes by Gee, Marvin H., Han, Arnold, Lofgren, Shane M., Beausang, John F., Mendoza, Juan L., Birnbaum, Michael E., Bethune, Michael T., Fischer, Suzanne, Yang, Xinbo, Gomez-Eerland, Raquel, Bingham, David B., Sibener, Leah V., Fernandes, Ricardo A., Velasco, Andrew, Baltimore, David, Schumacher, Ton N., Khatri, Purvesh, Quake, Stephen R., Davis, Mark M., Garcia, K. Christopher

“…The immune system can mount T cell responses against tumors; however, the antigen specificities of tumor-infiltrating lymphocytes (TILs) are not well…”
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Structure–function of type I and III interferons by de Weerd, Nicole A, Kurowska, Aleksandra K, Mendoza, Juan L, Schreiber, Gideon

“…Type I and type III interferons (IFNs) are major components in activating the innate immune response. Common to both are two distinct receptor chains…”
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Tensor-Network Method to Simulate Strongly Interacting Quantum Thermal Machines by Brenes, Marlon, Mendoza-Arenas, Juan José, Purkayastha, Archak, Mitchison, Mark T., Clark, Stephen R., Goold, John

“…We present a methodology to simulate the quantum thermodynamics of thermal machines which are built from an interacting working medium in contact with…”
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T cell receptor cross-reactivity expanded by dramatic peptide–MHC adaptability by Riley, Timothy P., Hellman, Lance M., Gee, Marvin H., Mendoza, Juan L., Alonso, Jesus A., Foley, Kendra C., Nishimura, Michael I., Vander Kooi, Craig W., Garcia, K. Christopher, Baker, Brian M.

“…T cell receptor cross-reactivity allows a fixed T cell repertoire to respond to a much larger universe of potential antigens. Recent work has emphasized the…”
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Factors Associated With Major Lower Extremity Amputations in Diabetic Foot Infections at a County Hospital in Guatemala by Reyna, Tanya, Flores, Miranda, Quiñonez, Eugenia, Mendoza, Juan A., Corzo, Victor F., Ortiz, Cesar, Huerta, Sergio

“…Outcomes from diabetic foot infections (DFIs) at the major referral hospital (Hospital Nacional de San Benito) in El Petén, Guatemala have not been analyzed…”
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Only the carrot, not the stick: incorporating trust into the enforcement of regulation by Mendoza, Juan P, Wielhouwer, Jacco L

“…New enforcement strategies allow agents to gain the regulator's trust and consequently face a lower audit probability. Prior research suggests that, in order…”
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Unsafe Practices of Motorcycle Riders in El Petén, Guatemala: A Community Observational Study and a Retrospective Institutional Review by Flores, Miranda, Reyna, Tanya, Quiñonez, Eugenia, Mendoza, Juan A., Corzo, Victor F., Ortiz, Cesar, Huerta, Sergio

“…Outcomes from trauma at the major referral hospital [Hospital Nacional de San Benito (HNSB)] in El Petén, Guatemala, have not been analyzed. Empirical evidence…”
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Sleep actigraphy results and HIV health outcomes in an urban HIV clinic sample by Esquivel-Mendoza, Juan A, Rogers, Brooke G, Safren, Steven A

“…Sleep disorders are prevalent and interfering conditions that affect people living with HIV (PLWH) at higher rates than the general population. Lower quality…”
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The IFN-λ-IFN-λR1-IL-10Rβ Complex Reveals Structural Features Underlying Type III IFN Functional Plasticity by Mendoza, Juan L., Schneider, William M., Hoffmann, Hans-Heinrich, Vercauteren, Koen, Jude, Kevin M., Xiong, Anming, Moraga, Ignacio, Horton, Tim M., Glenn, Jeffrey S., de Jong, Ype P., Rice, Charles M., Garcia, K. Christopher

“…Type III interferons (IFN-λs) signal through a heterodimeric receptor complex composed of the IFN-λR1 subunit, specific for IFN-λs, and interleukin-10Rβ…”
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Velocity Estimation From a Single Linear Motion Blurred Image Using Discrete Cosine Transform by Cortes-Osorio, Jimy Alexander, Gomez-Mendoza, Juan Bernardo, Riano-Rojas, Juan Carlos

“…There is a growing trend to use a digital camera as an instrument to measure velocity instead of a regular sensor approach. This paper introduces a new…”
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