Search Results - "Mendla, K D"

Cloning and functional characterization of a human A1 adenosine receptor by Libert, F, Van Sande, J, Lefort, A, Czernilofsky, A, Dumont, J E, Vassart, G, Ensinger, H A, Mendla, K D

“…A human brain hippocampus cDNA library was screened by hybridization with a dog A1 adenosine receptor cDNA probe. Sequencing of the resulting clones identified…”
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WAL 2014--a muscarinic agonist with preferential neuron-stimulating properties by Ensinger, H A, Doods, H N, Immel-Sehr, A R, Kuhn, F J, Lambrecht, G, Mendla, K D, Müller, R E, Mutschler, E, Sagrada, A, Walther, G

“…The ability of WAL 2014 to elicit muscarinic responses was investigated in various in vitro and in vivo models. In CHO cells transfected with human m1- or m3-…”
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Therapeutic potential of CNS-active M2 antagonists: novel structures and pharmacology by Doods, H N, Quirion, R, Mihm, G, Engel, W, Rudolf, K, Entzeroth, M, Schiavi, G B, Ladinsky, H, Bechtel, W D, Ensinger, H A

“…Clinical trials with muscarinic agonists or acetylcholine esterase inhibitors for the treatment of Alzheimer's dementia have shown disappointing or equivocal…”
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WAL 2014 FU (Talsaclidine) : A preferentially neuron activating muscarinic agonist for the treatment of Alzheimer's disease: Challenges and opportunities for developing muscarinic receptor subtype-based therapeutic agents by ENSINGER, H. A, BECHTEL, W.-D, BIRKE, F. W, MENDLA, K. D, MIERAU, J, SPECK, G, TRÖGER, W

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Talsaclidine (WAL 2014 FU), a muscarinic M 1 receptor agonist for the treatment of Alzheimer's disease by Wienrich, Marion, Ceci, Angelo, Ensinger, Helmut A., Gaida, Wolfram, Mendla, Klaus D., Osugi, Takeshi, Raschig, Andreas, Weiser, Thomas

“…Abstract Since the discovery of muscarinic receptor subtypes, extensive research has been going on attempting to provide treatments for diseases related to…”
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WAL 2014 FU (talsaclidine): A preferentially neuron activating muscarinic agonist for the treatment of Alzheimer's disease by Ensinger, Helmut A., Bechtel, Wolf-Dieter, Birke, Franz W., Mendla, Klaus D., Mierau, Joachim, Speck, Georg, Tröger, Wolfgang

“…The functional selectivity of WAL 2014 FU with regard to stimulation of the neuronal muscarinic M1 receptor subtype in vitro and in vivo is shown in different…”
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