Search Results - "Mendez, Raul"
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CPEB4 Increases Expression of PFKFB3 to Induce Glycolysis and Activate Mouse and Human Hepatic Stellate Cells, Promoting Liver Fibrosis
Published in Gastroenterology (New York, N.Y. 1943) (01-07-2020)“…We investigated mechanisms of hepatic stellate cell (HSC) activation, which contributes to liver fibrogenesis. We aimed to determine whether activated HSCs…”
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2
Tridimensional Combined Gluteoplasty: Liposuction, Buttock Implants, and Fat Transfer
Published in Plastic and reconstructive surgery (1963) (01-07-2020)“…There are different procedures for gluteal augmentation. The authors describe their gluteal augmentation technique, which combines buttock implant placement,…”
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3
Drivers of the time-varying heat-cold-mortality association in Spain: A longitudinal observational study
Published in Environment international (01-12-2023)“…A number of studies have reported reductions in mortality risk due to heat and cold over time. However, questions remain about the drivers of these adaptation…”
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Sequential Functions of CPEB1 and CPEB4 Regulate Pathologic Expression of Vascular Endothelial Growth Factor and Angiogenesis in Chronic Liver Disease
Published in Gastroenterology (New York, N.Y. 1943) (01-04-2016)“…Background & Aims Vascular endothelial growth factor (VEGF) regulates angiogenesis, yet therapeutic strategies to disrupt VEGF signaling can interfere with…”
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5
Lymphopenic Community Acquired Pneumonia (L-CAP), an Immunological Phenotype Associated with Higher Risk of Mortality
Published in EBioMedicine (01-10-2017)“…The role of neutrophil and lymphocyte counts in blood as prognosis predictors in Community Acquired Pneumonia (CAP) has not been adequately studied. This was a…”
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Disruption of negative feedback loop between vasohibin‐1 and vascular endothelial growth factor decreases portal pressure, angiogenesis, and fibrosis in cirrhotic rats
Published in Hepatology (Baltimore, Md.) (01-08-2014)“…Pathological angiogenesis represents a critical hallmark for chronic liver diseases. Understanding the mechanisms regulating angiogenesis is essential to…”
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Reversal of portal hypertension and hyperdynamic splanchnic circulation by combined vascular endothelial growth factor and platelet‐derived growth factor blockade in rats
Published in Hepatology (Baltimore, Md.) (01-10-2007)“…Vascular endothelial growth factor (VEGF) and platelet‐derived growth factor (PDGF) pathways are crucial to angiogenesis, a process that contributes…”
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Translational control by CPEB: a means to the end
Published in Nature reviews. Molecular cell biology (01-07-2001)“…The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development, and modulation of…”
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Global Analysis of CPEBs Reveals Sequential and Non-Redundant Functions in Mitotic Cell Cycle
Published in PloS one (23-09-2015)“…CPEB (Cytoplasmic Polyadenylation Element Binding) proteins are a family of four RNA-binding proteins that regulate the translation of maternal mRNAs…”
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10
The role of the gut microbiota in schizophrenia: Current and future perspectives
Published in The world journal of biological psychiatry (17-11-2018)“…Schizophrenia is a poorly understood chronic disease. Its pathophysiology is complex, dynamic, and linked to epigenetic mechanisms and microbiota involvement…”
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11
The Functional Topography of the Arabidopsis Genome Is Organized in a Reduced Number of Linear Motifs of Chromatin States
Published in The Plant cell (01-06-2014)“…Chromatin is of major relevance for gene expression, cell division, and differentiation. Here, we determined the landscape of Arabidopsis thaliana chromatin…”
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12
Estimation of Safety Performance Functions (SPF) at signalized intersections in Medellín Colombia
Published in Dyna (Medellín, Colombia) (01-07-2020)“…One of the objectives of road infrastructure sustainability is to ensure that users are treated equally and their quality of life is improved by providing…”
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13
Mutation bias favors protein folding stability in the evolution of small populations
Published in PLoS computational biology (01-05-2010)“…Mutation bias in prokaryotes varies from extreme adenine and thymine (AT) in obligatory endosymbiotic or parasitic bacteria to extreme guanine and cytosine…”
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14
Differential gene regulatory pattern in the human brain from schizophrenia using transcriptomic-causal network
Published in BMC bioinformatics (21-10-2020)“…Abstract Background Common and complex traits are the consequence of the interaction and regulation of multiple genes simultaneously, therefore characterizing…”
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Targeting the cytoplasmic polyadenylation element-binding protein CPEB4 protects against diet-induced obesity and microbiome dysbiosis
Published in Molecular metabolism (Germany) (01-12-2021)“…Obesity represents a growing health problem that is reaching pandemic dimensions and lacks effective cures, thus highlighting an urgent need for better…”
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New Sepsis Definition (Sepsis-3) and Community-acquired Pneumonia Mortality. A Validation and Clinical Decision-Making Study
Published in American journal of respiratory and critical care medicine (15-11-2017)“…The Sepsis-3 Task Force updated the clinical criteria for sepsis, excluding the need for systemic inflammatory response syndrome (SIRS) criteria. The clinical…”
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Progesterone and insulin stimulation of CPEB-dependent polyadenylation is regulated by Aurora A and glycogen synthase kinase-3
Published in Genes & development (01-01-2004)“…Progesterone stimulation of Xenopus oocyte maturation requires the cytoplasmic polyadenylation-induced translation of mos and cyclin B mRNAs. One cis element…”
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Cefto Real-Life Study: Real-World Data on the Use of Ceftobiprole in a Multicenter Spanish Cohort
Published in Antibiotics (Basel) (21-07-2023)“…Ceftobiprole is a fifth-generation cephalosporin that has been approved in Europe solely for the treatment of community-acquired and nosocomial pneumonia. The…”
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From classical mendelian randomization to causal networks for systematic integration of multi-omics
Published in Frontiers in genetics (15-09-2022)“…The number of studies with information at multiple biological levels of granularity, such as genomics, proteomics, and metabolomics, is increasing each year,…”
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Structure and non-structure of centrosomal proteins
Published in PloS one (09-05-2013)“…Here we perform a large-scale study of the structural properties and the expression of proteins that constitute the human Centrosome. Centrosomal proteins tend…”
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