Search Results - "Mendes Giannini, Maria Jose Soares"
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Fungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy?
Published in International journal of nanomedicine (01-01-2016)“…Invasive mycoses are a major problem for immunocompromised individuals and patients in intensive care units. Morbidity and mortality rates of these infections…”
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Gene expression of Paracoccidioides virulence factors after interaction with macrophages and fibroblasts
Published in Memórias do Instituto Oswaldo Cruz (01-01-2021)“…Paracoccidioidomycosis (PCM) is a systemic mycosis with high prevalence in Latin America that is caused by thermodimorphic fungal species of the…”
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Nanotechnology-Based Approaches for Voriconazole Delivery Applied to Invasive Fungal Infections
Published in Pharmaceutics (12-01-2023)“…Invasive fungal infections increase mortality and morbidity rates worldwide. The treatment of these infections is still limited due to the low bioavailability…”
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Influence of Zinc on Histoplasma capsulatum Planktonic and Biofilm Cells
Published in Journal of fungi (Basel) (20-05-2024)“…causes a fungal respiratory disease. Some studies suggest that the fungus requires zinc to consolidate the infection. This study aimed to investigate the…”
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Synthesis and Evaluation of the Antifungal and Toxicological Activity of Nitrofuran Derivatives
Published in Pharmaceutics (08-03-2022)“…Fungal diseases affect more than 1 billion people worldwide. The constant global changes, the advent of new pandemics, and chronic diseases favor the diffusion…”
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Evaluation of the Anti- Histoplasma capsulatum Activity of Indole and Nitrofuran Derivatives and Their Pharmacological Safety in Three-Dimensional Cell Cultures
Published in Pharmaceutics (12-05-2022)“…is a fungus that causes histoplasmosis. The increased evolution of microbial resistance and the adverse effects of current antifungals help new drugs to…”
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Polypeptides Targeting Paracoccidioides brasiliensis Drk1
Published in Journal of fungi (Basel) (29-09-2023)“…Considering the toxicity of conventional therapeutic approaches and the importance of precise mechanistic targets, it is important to explore signaling…”
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Paracoccidoides brasiliensis 30 kDa adhesin: identification as a 14-3-3 protein, cloning and subcellular localization in infection models
Published in PloS one (30-04-2013)“…Paracoccidoides brasiliensis adhesion to lung epithelial cells is considered an essential event for the establishment of infection and different proteins…”
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Drk1, a Dimorphism Histidine Kinase, Contributes to Morphology, Virulence, and Stress Adaptation in Paracoccidioides brasiliensis
Published in Journal of fungi (Basel) (12-10-2021)“…P. brasiliensis is a thermally dimorphic fungus belonging to Paracoccidioides complex, causative of a systemic, endemic mycosis limited to Latin American…”
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Candida auris: Epidemiology, risk factors, virulence, resistance, and therapeutic options
Published in Microbial pathogenesis (01-12-2018)“…Candida auris emerged as a pathogen resistant to multiple antifungal and has been associated with nosocomial outbreaks with high transmission capacity between…”
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Effectiveness of Disinfectants Used in Hemodialysis against both Candida orthopsilosis and C. parapsilosis Sensu Stricto Biofilms
Published in Antimicrobial Agents and Chemotherapy (01-05-2013)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Species diversity of yeast in oral colonization of insulin-treated diabetes mellitus patients
Published in Mycopathologia (1975) (01-08-2006)“…The aim of this study was to investigate oral yeast colonization, antifungal susceptibility and strain diversity in insulin-dependent diabetes mellitus…”
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Identification of Off-Patent Drugs That Show Synergism with Amphotericin B or That Present Antifungal Action against Cryptococcus neoformans and Candida spp
Published in Antimicrobial agents and chemotherapy (24-03-2020)“…Amphotericin B (AmB) is the antifungal with the strongest fungicidal activity, but its use has several limitations, mainly associated with its toxicity…”
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14
Transcriptional profile of a bioethanol production contaminant Candida tropicalis
Published in AMB Express (11-10-2018)“…The fermentation process is widely used in the industry for bioethanol production. Even though it is widely used, microbial contamination is unpredictable and…”
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In Vitro and In Vivo Effect of Peptides Derived from 14-3-3 Paracoccidioides spp. Protein
Published in Journal of fungi (Basel) (13-01-2021)“…Paracoccidioidomycosis (PCM) is a chronic disease that causes sequelae and requires prolonged treatment; therefore, new therapeutic approaches are necessary…”
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Alterations of protein expression in conditions of copper-deprivation for Paracoccidioides lutzii in the presence of extracellular matrix components
Published in BMC microbiology (13-12-2014)“…Paracoccidioides spp is a fungi genus and the agent of paracoccidioidomycosis. The strategies of infection used by these pathogens involve the expression of…”
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Mechanism of action and relationship between structure and biological activity of Ctx-Ha: a new ceratotoxin-like peptide from Hypsiboas albopunctatus
Published in Protein and peptide letters (01-06-2012)“…The increase in bacterial resistance to current antibiotics has led to the development of new active molecules. We have isolated the antimicrobial peptide…”
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Environmental isolation, biochemical identification, and antifungal drug susceptibility of Cryptococcus species
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-11-2013)“…The incidence of opportunistic fungal infections has increased in recent years and is considered an important public health problem. Among systemic and…”
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Binding of extracellular matrix proteins to Paracoccidioides brasiliensis
Published in Microbes and infection (01-05-2006)“…Adhesion to extracellular matrix (ECM) proteins plays a crucial role in invasive fungal diseases. ECM proteins bind to the surface of Paracoccidioides…”
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Antifungal Activity of Decyl Gallate against Several Species of Pathogenic Fungi
Published in Evidence-based complementary and alternative medicine (01-01-2014)“…This work aims to demonstrate that the gallic acid structure modification to the decyl gallate (G14) compound contributed to increase the antifungal activity…”
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