Search Results - "Mendell, LM"

Nerve growth factor and nociception by Lewin, G R, Mendell, L M

“…Nerve growth factor (NGF) is thought of as a target-derived factor responsible for the survival and maintaining the phenotype of specific sets of peripheral…”
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Mechanisms of sensitization of the response of single dorsal root ganglion cells from adult rat to noxious heat by Galoyan, Samuel M., Petruska, Jeffrey C., Mendell, Lorne M.

“…We investigated the regulation by nerve growth factor of the response of sensory neurons to noxious heat (>43 °C). In dissociated dorsal root ganglion neurons…”
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Somal membrane properties of physiologically identified sensory neurons in the rat: effects of nerve growth factor by Ritter, A M, Mendell, L M

“…1. Intracellular recordings were made in situ from physiologically identified dorsal root ganglion (DRG) cells in untreated rats aged 5-8 wk and in rats…”
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Characteristics of nerve growth factor induced hyperalgesia in adult rats: dependence on enhanced bradykinin-1 receptor activity but not neurokinin-1 receptor activation by Rueff, A, Dawson, A J, Mendell, L M

“…Treatment of adult rats with a single dose of nerve growth factor (NGF, 1 mg/kg, i.p.) results in a prolonged hypersensitivity to noxious thermal stimulation…”
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Nerve growth factor-induced hyperalgesia in the neonatal and adult rat by Lewin, GR, Ritter, AM, Mendell, LM

“…Recently, we have shown that the interaction between NGF and sensory neurons in early postnatal periods is restricted to nociceptive afferents (Ritter et al.,…”
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The size principle: a rule describing the recruitment of motoneurons by Mendell, Lorne M

“…This essay looks at the historical significance of five APS classic papers that are freely available online: McPhedran AM, Wuerker RB, and Henneman E…”
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Quantitative ultrastructure of Ia boutons in the ventral horn: scaling and positional relationships by Pierce, JP, Mendell, LM

“…Three physiologically characterized spindle (group Ia) afferents were labeled by the intracellular injection of HRP and were processed for light-level…”
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Central sprouting and functional plasticity of regenerated primary afferents by Koerber, HR, Mirnics, K, Brown, PB, Mendell, LM

“…A combination of neuroanatomical and electrophysiological techniques was used to study the effects of peripheral axotomy and regeneration of primary afferents…”
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The many functions of nerve growth factor: multiple actions on nociceptors by Petruska, Jeffrey C., Mendell, Lorne M.

“…Nerve growth factor (NGF) initially interested neurobiologists because of its effects in the developing nervous system. It is now clear that NGF functions…”
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Acute Sensitization by NGF of the Response of Small-Diameter Sensory Neurons to Capsaicin by Shu, X, Mendell, L. M

“…Department of Neurobiology and Behavior, State University of New York at Stony Brook, Stony Brook, New York 11794-5230 Shu, X. and L. M. Mendell. Acute…”
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BDNF sensitizes the response of lamina II neurons to high threshold primary afferent inputs by Garraway, Sandra M., Petruska, Jeffrey C., Mendell, Lorne M.

“…Brain‐derived neurotrophic factor (BDNF) is up‐regulated and released in the dorsal horn following peripheral inflammation and has therefore been implicated in…”
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Neurotrophins and Hyperalgesia by X-Q. Shu, Mendell, L. M.

“…Nerve growth factor (NGF), a member of the neurotrophin family, is crucial for survival of nociceptive neurons during development. Recently, it has been shown…”
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Nerve growth factor acutely sensitizes the response of adult rat sensory neurons to capsaicin by Shu, Xiaoquan, Mendell, Lorne M

“…Perforated patch clamp recordings were made from 118 voltage clamped (−60 mV), capsaicin-responsive dorsal root ganglion (DRG) cells (<30 μ) maintained in…”
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Peripheral and central mechanisms of NGF-induced hyperalgesia by Lewin, G R, Rueff, A, Mendell, L M

“…Mechanisms underlying the hyperalgesia induced by a single systemic injection of nerve growth factor (NGF) in adult rats were studied in vivo. A single dose of…”
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A Developmental Switch in Acute Sensitization of Small Dorsal Root Ganglion (DRG) Neurons to Capsaicin or Noxious Heating by NGF by Zhu, Weiguo, Galoyan, Sam M, Petruska, Jeffrey C, Oxford, Gerry S, Mendell, Lorne M

“…1 Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana 46202; and 2 Department of Neurobiology and Behavior,…”
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Neurotrophins, nociceptors, and pain by Mendell, Lorne M., Albers, Kathryn M., Davis, Brian M.

“…It is now well established that neurotrophins play a crucial role in the development of the nervous system. However, there is increasing evidence that the…”
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Acute modulation of synaptic transmission to motoneurons by BDNF in the neonatal rat spinal cord by Arvanian, Victor L., Mendell, Lorne M.

“…We investigated the acute effects of bath applied BDNF on synaptic input to motoneurons in the hemisected spinal cord of the neonatal rat. Motoneurons were…”
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Combined delivery of neurotrophin-3 and NMDA receptors 2D subunit strengthens synaptic transmission in contused and staggered double hemisected spinal cord of neonatal rat by Arvanian, Victor L., Bowers, William J., Anderson, Aileen, Horner, Philip J., Federoff, Howard J., Mendell, Lorne M.

“…We investigated whether administration of neurotrophin-3 (NT-3) and NMDA-2D-expressing units, found previously to enhance transmission in neonatal rat spinal…”
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Assessing the Decade of the Brain by Jones, Edward G., Mendell, Lorne M.

“…Public recognition of the importance of studies of the spinal cord, brain, behavior, and mind is evident in the remarkable bipartican congressional support for…”
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Neurotrophins and synaptic plasticity in the mammalian spinal cord by Mendell, Lorne M., Munson, John B., Arvanian, Victor L.

“…The pathway mediating the monosynaptic stretch reflex has served as an important model system for studies of plasticity in the spinal cord. Its usefulness is…”
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