Search Results - "Mencalha, André"

Forkhead box M1 (FoxM1) gene is a new STAT3 transcriptional factor target and is essential for proliferation, survival and DNA repair of K562 cell line by Mencalha, André L, Binato, Renata, Ferreira, Gerson M, Du Rocher, Barbara, Abdelhay, Eliana

“…The forkhead box (Fox) M1 gene belongs to a superfamily of evolutionarily conserved transcriptional regulators that are involved in a wide range of biological…”
Get full text

Regulation Is in the Air: The Relationship between Hypoxia and Epigenetics in Cancer by Camuzi, Diego, de Amorim, Ísis Salviano Soares, Ribeiro Pinto, Luis Felipe, Oliveira Trivilin, Leonardo, Mencalha, André Luiz, Soares Lima, Sheila Coelho

“…Hypoxia is an inherent condition of tumors and contributes to cancer development and progression. Hypoxia-inducible factors (HIFs) are the major transcription…”
Get full text

Computational modeling of the bHLH domain of the transcription factor TWIST1 and R118C, S144R and K145E mutants by Maia, Amanda M, da Silva, João Hm, Mencalha, André L, Caffarena, Ernesto R, Abdelhay, Eliana

“…Human TWIST1 is a highly conserved member of the regulatory basic helix-loop-helix (bHLH) transcription factors. TWIST1 forms homo- or heterodimers with E-box…”
Get full text

Inhibition of STAT3-interacting protein 1 (STATIP1) promotes STAT3 transcriptional up-regulation and imatinib mesylate resistance in the chronic myeloid leukemia by Mencalha, André L, Corrêa, Stephany, Salles, Daniela, Du Rocher, Bárbara, Santiago, Marcelo F, Abdelhay, Eliana

“…Signal transducer and activator of transcription 3 (STAT3) is an important transcriptional factor frequently associated with the proliferation and survival of…”
Get full text

NF-kappaB Is Involved in the Regulation of EMT Genes in Breast Cancer Cells by Pires, Bruno R B, Mencalha, Andre L, Ferreira, Gerson M, de Souza, Waldemir F, Morgado-Díaz, José A, Maia, Amanda M, Corrêa, Stephany, Abdelhay, Eliana S F W

“…The metastatic process in breast cancer is related to the expression of the epithelial-to-mesenchymal transition transcription factors (EMT-TFs) SNAIL, SLUG,…”
Get full text

A comparative proteomic study identified LRPPRC and MCM7 as putative actors in imatinib mesylate cross-resistance in Lucena cell line by Corrêa, Stephany, Pizzatti, Luciana, Du Rocher, Bárbara, Mencalha, André, Pinto, Daniela, Abdelhay, Eliana

“…Although chronic myeloid leukemia (CML) treatment has improved since the introduction of imatinib mesylate (IM), cases of resistance have been reported. This…”
Get full text

Metformin prevention of doxorubicin resistance in MCF-7 and MDA-MB-231 involves oxidative stress generation and modulation of cell adaptation genes by Marinello, Poliana Camila, Panis, Carolina, Silva, Thamara Nishida Xavier, Binato, Renata, Abdelhay, Eliana, Rodrigues, Juliana Alves, Mencalha, André Luiz, Lopes, Natália Medeiros Dias, Luiz, Rodrigo Cabral, Cecchini, Rubens, Cecchini, Alessandra Lourenço

“…Metformin was shown to sensitize multidrug resistant breast cancer cells; however, the mechanisms involved in this capacity need to be clarified. We…”
Get full text

FOXM1 targets XIAP and Survivin to modulate breast cancer survival and chemoresistance by Nestal de Moraes, Gabriela, Delbue, Deborah, Silva, Karina L., Robaina, Marcela Cristina, Khongkow, Pasarat, Gomes, Ana R., Zona, Stefania, Crocamo, Susanne, Mencalha, André Luiz, Magalhães, Lídia M., Lam, Eric W.-F., Maia, Raquel C.

“…Drug resistance is a major hurdle for successful treatment of breast cancer, the leading cause of deaths in women throughout the world. The FOXM1 transcription…”
Get full text

Post-translational modifications disclose a dual role for redox stress in cardiovascular pathophysiology by Victorino, Vanessa Jacob, Mencalha, André Luiz, Panis, Carolina

“…Although some of the redox changes that occur in biological components may result in deleterious events, this process has recently been tackled as a modulatory…”
Get full text

Necroptosis as a consequence of photodynamic therapy in tumor cells by de Souza, Álvaro Carneiro, Mencalha, André Luiz, Fonseca, Adenilson de Souza da, de Paoli, Flávia

“…Photodynamic therapy (PDT) is an alternative to cancer treatment, demonstrating selectivity and significant cytotoxicity on malignant tissues. Such therapy…”
Get full text

Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development by Mencalha, André L, Corrêa, Stephany, Abdelhay, Eliana

“…Calcium-dependent protein kinases (PKCs) function in a myriad of cellular processes, including cell-cycle regulation, proliferation, hematopoietic stem cell…”
Get full text

Low-power infrared laser modulates telomere length in heart tissue from an experimental model of acute lung injury by da Silva Neto Trajano, Larissa Alexsandra, da Silva Sergio, Luiz Philippe, de Oliveira, Diego Sá Leal, Trajano, Eduardo Tavares Lima, Dos Santos Silva, Marco Aurélio, de Paoli, Flavia, Mencalha, André Luiz, de Souza da Fonseca, Adenilson

“…Acute lung injury and acute respiratory distress syndrome can occur as a result of sepsis. Cardiac dysfunction is a serious component of multi-organ failure…”
Get more information

Progeny From Irradiated Colorectal Cancer Cells Acquire an EMT-Like Phenotype and Activate Wnt/β-Catenin Pathway by Bastos, Lilian Gonçalves dos Reis, de Marcondes, Priscila Guimarães, de-Freitas-Junior, Julio Cesar Madureira, Leve, Fernanda, Mencalha, André Luiz, de Souza, Waldemir Fernandes, de Araujo, Wallace Martins, Tanaka, Marcelo Neves, Abdelhay, Eliana Saul Furquim Werneck, Morgado-Díaz, José Andrés

“…ABSTRACT Radiotherapy remains a major approach to adjuvant therapy for patients with advanced colorectal cancer, however, the fractionation schedules…”
Get full text

Low ABCB1 and high OCT1 levels play a favorable role in the molecular response to imatinib in CML patients in the community clinical practice by da Cunha Vasconcelos, Flavia, Mauricio Scheiner, Marcos Antonio, Moellman-Coelho, Arthur, Mencalha, André Luiz, Renault, Ilana Zalcberg, Rumjanek, Vivian Mary, Maia, Raquel Ciuvalschi, MD, PhD

“…Highlights • Low ABCB1 and high OCT1 mRNA levels are associated with an optimal imatinib response in CML patients. • Overall survival at 8-years in CML…”
Get full text

Photobiomodulation by dual-wavelength low-power laser effects on infected pressure ulcers by Thomé Lima, Andrezza Maria Côrtes, da Silva Sergio, Luiz Philippe, da Silva Neto Trajano, Larissa Alexsandra, de Souza, Bianca Paschoal, da Motta Mendes, João Pedro, Cardoso, Adriano Fonseca Ribeiro, Figueira, Caroline Pisa, dos Anjos Tavares, Beatriz, Figueira, Daniella Sousa, Mencalha, André Luiz, Trajano, Eduardo Tavares Lima, de Souza da Fonseca, Adenilson

“…The aim of this study was to evaluate the effects of photobiomodulation (PBM) by dual-wavelength low-power lasers on the healing and bacterial bioburden of…”
Get full text

Conserved transcription factor binding sites suggest an activator basal promoter and a distal inhibitor in the galanin gene promoter in mouse ES cells by Gonzalez, Sayonara, Binato, Renata, Guida, Letícia, Mencalha, André Luiz, Abdelhay, Eliana

“…Galanin and its receptors have been shown to be expressed in undifferentiated mouse embryonic stem (ES) cells through transcriptome and proteomic analyses…”
Get full text

Cell viability, reactive oxygen species, apoptosis, and necrosis in myoblast cultures exposed to low-level infrared laser by Alexsandra da Silva Neto Trajano, Larissa, da Silva, Camila Luna, de Carvalho, Simone Nunes, Cortez, Erika, Mencalha, André Luiz, de Souza da Fonseca, Adenilson, Stumbo, Ana Carolina

“…Low-level infrared laser is considered safe and effective for treatment of muscle injuries. However, the mechanism involved on beneficial effects of laser…”
Get full text

Apoptosis induction of cardiomyocytes and subsequent fibrosis after irradiation and neoadjuvant chemotherapy by Salata, Camila, Ferreira-Machado, Samara Cristina, De Andrade, Cherley Borba Vieira, Mencalha, André Luiz, Mandarim-De-Lacerda, Carlos Alberto, de Almeida, Carlos Eduardo

“…Abstract Purpose: Breast cancer treatments can induce important cardiovascular complications. The aim of this study was to evaluate cardiac alterations after…”
Get full text

Neonatal overfeeding impairs differentiation potential of mice subcutaneous adipose mesenchymal stem cells by Dias, Isabelle, Salviano, Ísis, Mencalha, André, de Carvalho, Simone Nunes, Thole, Alessandra Alves, Carvalho, Laís, Cortez, Erika, Stumbo, Ana Carolina

“…Nutritional changes in the development (intrauterine life and postnatal period) may trigger long-term pathophysiological complications such as obesity and…”
Get full text

High-Resolution Melting Analysis for Rapid Detection of Mutations in Patients with FGFR3 -Related Skeletal Dysplasias by Riba, Fernanda Rolemberg G, Gomes, Maria E S, Rabelo, Natana Chaves, Zuma, Maria Celia C, Llerena, Juan C, Mencalha, André Luiz, Gonzalez, Sayonara

“…Mutations in the fibroblast growth factor receptor 3 (FGFR3) gene are related to skeletal dysplasias (SDs): acondroplasia (ACH), hypochodroplasia (HCH) and…”
Get more information