Search Results - "Memon, Tosifa"
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The Cytochrome P450 2C83 Variant (rs11572080) Is Associated with Improved Asthma Symptom Control in Children and Altered Lipid Mediator Production and Inflammatory Response in Human Bronchial Epithelial Cells
Published in Drug metabolism and disposition (01-08-2024)“…This study investigated an association between the cytochrome P450 (CYP) 2C8*3 polymorphism with asthma symptom control in children and changes in lipid…”
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Journal Article -
2
Wood Smoke Particles Stimulate MUC5AC Overproduction by Human Bronchial Epithelial Cells Through TRPA1 and EGFR Signaling
Published in Toxicological sciences (01-04-2020)“…Abstract Mucus hypersecretion is a pathological feature of acute inflammatory and chronic obstructive pulmonary diseases. Exposure to air pollutants can be a…”
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Journal Article -
3
Transient Receptor Potential Ankyrin-1 and Vanilloid-3 Differentially Regulate Endoplasmic Reticulum Stress and Cytotoxicity in Human Lung Epithelial Cells After Pneumotoxic Wood Smoke Particle Exposure
Published in Molecular pharmacology (01-11-2020)“…This study investigated the roles of transient receptor potential (TRP) ankyrin-1 (TRPA1) and TRP vanilloid-3 (TRPV3) in regulating endoplasmic reticulum…”
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Dynamic Expression of Transient Receptor Potential Vanilloid-3 and Integrated Signaling with Growth Factor Pathways during Lung Epithelial Wound Repair following Wood Smoke Particle and Other Forms of Lung Cell Injury
Published in Molecular pharmacology (01-09-2021)“…Prior studies revealed increased expression of the transient receptor potential vanilloid-3 (TRPV3) ion channel after wood smoke particulate matter (WSPM)…”
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Journal Article -
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Inhibition of TRPA1, Endoplasmic Reticulum Stress, Human Airway Epithelial Cell Damage, and Ectopic MUC5AC Expression by Vasaka ( Adhatoda vasica ; Malabar Nut) Tea
Published in Pharmaceuticals (Basel, Switzerland) (17-06-2023)“…This study tested whether a medicinal plant, Vasaka, typically consumed as a tea to treat respiratory malaise, could protect airway epithelial cells (AECs)…”
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Journal Article -
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Using constellation pharmacology to define comprehensively a somatosensory neuronal subclass
Published in Proceedings of the National Academy of Sciences - PNAS (11-02-2014)“…Change is intrinsic to nervous systems; change is required for learning and conditioning and occurs with disease progression, normal development, and aging. To…”
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Journal Article -
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Characterization of two neuronal subclasses through constellation pharmacology
Published in Proceedings of the National Academy of Sciences - PNAS (31-07-2012)“…Different types of neurons diverge in function because they express their own unique set or constellation of signaling molecules, including receptors and ion…”
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Journal Article -
8
Comparative functional expression of nAChR subtypes in rodent DRG neurons
Published in Frontiers in cellular neuroscience (28-11-2013)“…We investigated the functional expression of nicotinic acetylcholine receptors (nAChRs) in heterogeneous populations of dissociated rat and mouse lumbar dorsal…”
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Journal Article -
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trans -Anethole of Fennel Oil is a Selective and Nonelectrophilic Agonist of the TRPA1 Ion Channel
Published in Molecular pharmacology (01-04-2019)“…Transient receptor potential (TRP) cation channels are molecular targets of various natural products. TRPA1, a member of TRP channel family, is specifically…”
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Journal Article -
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TRPA1 expression levels and excitability brake by KV channels influence cold sensitivity of TRPA1-expressing neurons
Published in Neuroscience (14-06-2017)“…Highlights • Three distinct subclasses of sensory neurons mediate cold responses. • Cold responses in TRPA1-expressing neurons depend on TRPA1 and not TRPM8…”
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Journal Article -
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Inhibition of TRPA1, Endoplasmic Reticulum Stress, Human Airway Epithelial Cell Damage, and Ectopic IMUC5AC/I Expression by Vasaka Tea
Published in Pharmaceuticals (Basel, Switzerland) (01-06-2023)“…This study tested whether a medicinal plant, Vasaka, typically consumed as a tea to treat respiratory malaise, could protect airway epithelial cells (AECs)…”
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Journal Article -
12
Differential Activation of TRPA1 by Diesel Exhaust Particles: Relationships between Chemical Composition, Potency, and Lung Toxicity
Published in Chemical research in toxicology (17-06-2019)“…Diesel exhaust particulate (DEP) causes pulmonary irritation and inflammation, which can exacerbate asthma and other diseases. These effects may arise from the…”
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Journal Article -
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TRPA1 expression levels and excitability brake by K V channels influence cold sensitivity of TRPA1-expressing neurons
Published in Neuroscience (14-06-2017)“…The molecular sensor of innocuous (painless) cold sensation is well-established to be transient receptor potential cation channel, subfamily M, member 8…”
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Journal Article -
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The Tunicate Metabolite 2‑(3,5-Diiodo-4-methoxyphenyl)ethan-1-amine Targets Ion Channels of Vertebrate Sensory Neurons
Published in ACS chemical biology (17-09-2021)“…Marine tunicates produce defensive amino-acid-derived metabolites, including 2-(3,5-diiodo-4-methoxyphenyl)ethan-1-amine (DIMTA), but their mechanisms of…”
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Journal Article -
15
Constellation Pharmacology of TRPM8- and TRPA1-Expressing Somatosensory Neurons
Published 01-01-2017“…Constellation pharmacology is an imaging platform that can be used to identify functionally relevant cell-types based on cell-specific combinations…”
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Dissertation -
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Rapid degradation of CdSe∕ZnS colloidal quantum dots exposed to gamma irradiation
Published in Applied physics letters (27-10-2008)“…Effects of Cs137 gamma irradiation on photoluminescent properties of CdSe∕ZnS colloidal quantum dots are reported. Optical degradation is evaluated by tracking…”
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Journal Article -
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Nanophosphors based on CdSe/ZnS and CdSe/SiO2 colloidal quantum dots for daylight-quality white LEDs
Published in CLEO/QELS: 2010 Laser Science to Photonic Applications (01-05-2010)“…Properly mixed combination of CdSe/ZnS and CdSe/SiO 2 colloidal quantum dots of different sizes is suggested as a nanophosphor material to be combined with…”
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Conference Proceeding -
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Rapid degradation of Cd Se ∕ Zn S colloidal quantum dots exposedto gamma irradiation
Published in Applied physics letters (28-10-2008)“…Effects of Cs 137 gamma irradiation on photoluminescent properties of Cd Se ∕ Zn S colloidal quantum dots are reported. Optical degradation is evaluated by…”
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Journal Article -
19
Nanophosphors based on CdSe/ZnS colloidal quantum dots for daylight-quality white LEDs
Published in 2010 International Conference on Nanoscience and Nanotechnology (01-02-2010)“…Properly mixed combination of CdSe/ZnS colloidal quantum dots of different sizes is suggested as a nanophosphor material to be combined with blue InGaN/GaN…”
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Conference Proceeding -
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Effects of gamma irradiation on optical properties of CdSe/ZnS colloidal quantum dots
Published in 2008 Conference on Lasers and Electro-Optics and 2008 Conference on Quantum Electronics and Laser Science (01-05-2008)“…Effects of 137 Cs gamma irradiation on photoluminescent properties of CdSe/ZnS colloidal quantum dots are reported. Optical degradation was evaluated by…”
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Conference Proceeding