Search Results - "Memon, Danish"

A resource of variant effect predictions of single nucleotide variants in model organisms by Wagih, Omar, Galardini, Marco, Busby, Bede P, Memon, Danish, Typas, Athanasios, Beltrao, Pedro

“…The effect of single nucleotide variants (SNVs) in coding and noncoding regions is of great interest in genetics. Although many computational methods aim to…”
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Pan‐Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival by Sousa, Abel, Dugourd, Aurelien, Memon, Danish, Petursson, Borgthor, Petsalaki, Evangelia, Saez‐Rodriguez, Julio, Beltrao, Pedro

“…Genetic alterations in cancer cells trigger oncogenic transformation, a process largely mediated by the dysregulation of kinase and transcription factor (TF)…”
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Individual COVID‐19 disease trajectories revealed by plasma proteomics by Memon, Danish, Barrio‐Hernandez, Inigo, Beltrao, Pedro

“…Since the start of 2020, the world has been upended by the pandemic caused by the severe acute respiratory coronavirus type 2 (SARS‐CoV‐2), the causative agent…”
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In silico prediction of housekeeping long intergenic non-coding RNAs reveals HKlincR1 as an essential player in lung cancer cell survival by Memon, Danish, Bi, Jing, Miller, Crispin J.

“…Prioritising long intergenic noncoding RNAs (lincRNAs) for functional characterisation is a significant challenge. Here we applied computational approaches to…”
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Prenatal diagnosis of obstructed supracardiac total anomalous pulmonary venous connection at 23 weeks with successful immediate postnatal surgical correction by Memon, Danish, Vaidyanathan, Balu

“…Diagnosis of isolated total anomalous pulmonary venous connections (TAPVCs) is relatively rare in fetal life, especially in early gestation. We report a case…”
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High-throughput functional characterization of protein phosphorylation sites in yeast by Viéitez, Cristina, Busby, Bede P., Ochoa, David, Mateus, André, Memon, Danish, Galardini, Marco, Yildiz, Umut, Trovato, Matteo, Jawed, Areeb, Geiger, Alexander G., Oborská-Oplová, Michaela, Potel, Clement M., Vonesch, Sibylle C., Szu Tu, Chelsea, Shahraz, Mohammed, Stein, Frank, Steinmetz, Lars M., Panse, Vikram G., Noh, Kyung-Min, Savitski, Mikhail M., Typas, Athanasios, Beltrao, Pedro

“…Phosphorylation is a critical post-translational modification involved in the regulation of almost all cellular processes. However, fewer than 5% of thousands…”
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Technique of interdigitating flaps for repair of abnormal origin of right pulmonary artery from ascending aorta by Salve, Gananjay G., Memon, Danish A.K., Manvi, Veeresh, Manvi, Nidhi G., Gan, Mohan D., Saldanha, Richard

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Publisher Correction: In silico prediction of housekeeping long intergenic non-coding RNAs reveals HKlincR1 as an essential player in lung cancer cell survival by Memon, Danish, Bi, Jing, Miller, Crispin J.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Open-heart surgery in preterm infants: A single-center experience by Memon, Danish, Bayya, Praveen Reddy, Bendapudi, Perraju, Jayashankar, Jessin Puliparambil, Kottayil, Brijesh Parayaru, Srimurugan, Balaji, Kumar, Raman Krishna

“…Open-heart surgery is challenging in preterm neonates and infants, and its feasibility in low-resource settings has not been defined. We describe our…”
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Systemic and Oligo-Acquired Resistance to PD-(L)1 Blockade in Lung Cancer by Schoenfeld, Adam J, Rizvi, Hira A, Memon, Danish, Shaverdian, Narek, Bott, Matthew J, Sauter, Jennifer L, Tsai, C Jillian, Lihm, Jayon, Hoyos, David, Plodkowski, Andrew J, Perez-Johnston, Rocio, Sawan, Peter, Egger, Jacklynn V, Greenbaum, Benjamin D, Rimner, Andreas, Riely, Gregory J, Rudin, Charles M, Rusch, Valerie W, Gomez, Daniel R, Hellmann, Matthew D

“…Clinical patterns and the associated optimal management of acquired resistance to PD-(L)1 blockade are poorly understood. All cases of metastatic lung cancer…”
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Copy number aberrations drive kinase rewiring, leading to genetic vulnerabilities in cancer by Memon, Danish, Gill, Michael B., Papachristou, Evangelia K., Ochoa, David, D’Santos, Clive S., Miller, Martin L., Beltrao, Pedro

“…Somatic DNA copy number variations (CNVs) are prevalent in cancer and can drive cancer progression, albeit with often uncharacterized roles in altering cell…”
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Hypertrophic cardiomyopathy in a case of familial HLH: Early screening saves life and favours better outcomes by Keerthana, Sarapu, Sampagar, Abhilasha, Memon, Danish

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833 CRB-601, a selective integrin αvβ8-blocking antibody, prevents TGFβ activation, promotes immune cell remodeling, and exhibits potent antitumor activity by Singh, Maneesh, Wang, Daqing, Shinde, Vaishali, Memon, Danish, Seed, Rob, Baron, Jody, Nishimura, Stephen, Brake, Rachael, Kolodziej, Andrew

“…BackgroundIn metastatic disease, Transforming growth factor-beta (TGFβ) signaling in the tumor microenvironment (TME) is associated with immune cell exclusion,…”
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1388 CRB-601, an integrin αvβ8 blocking antibody entering phase I: pre-clinical and translational biomarkers for indication selection by Shinde, Vaishali, Wang, Daqing, Memon, Danish, Singh, Maneesh, Rindone, James, Carter, Rodney, Muse, Naomi, Hodgson, Ian, Kolodziej, Andrew, Brake, Rachael

“…BackgroundTGFβ is a cytokine associated with immunosuppression in many metastatic solid tumors. Despite the known role that this pleotropic cytokine can play…”
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Adult-onset Primary Hemophagocytic Lymphohistiocytosis: Reporting a Rare Case with Review of Literature by Memon, Fatima, Ahmed, Jawad, Malik, Farheen, Ahmad, Junaid, Memon, Danish Ahmed

“…Hemophagocytic lymphohistiocytosis (HLH) is an uncommon, aggressive hematological syndrome. It is caused by an increased and unchecked proliferation of T…”
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Comparison of intravenous sildenafil with inhaled nitric oxide for acute vasodilator testing in pulmonary arterial hypertension by Kumar, Shine, Memon, Danish, Raj, Manu, Sen, Amitabh C., Jayasankar, Jessin P., Leeladharan, Sreelakshmi P., Sudhakar, Abish, Kumar, Raman K.

“…Acute vasodilator testing (AVT) identifies acute responders for initiation of calcium channel blockers in pulmonary arterial hypertension (PAH) and operability…”
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A global analysis of adaptive evolution of operons in cyanobacteria by Memon, Danish, Singh, Abhay K., Pakrasi, Himadri B., Wangikar, Pramod P.

“…Operons are an important feature of prokaryotic genomes. Evolution of operons is hypothesized to be adaptive and has contributed significantly towards…”
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Comparative analysis and implementation of DC microgrid systems versus AC microgrid performance by Memon, Danish Asad, Ali, Khawaja Haider, Memon, Abdul Aziz, Ansari, Jamshed Ahmed, Badar, Jahangeer, Alharbi, Mohammed, Banatwala, Ali Zain, Kumar, Manoj

“…DC power systems have emerged as a cost-effective solution for electric power generation and transmission, challenging the dominance of AC distribution…”
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing by Gordon, David E., Jang, Gwendolyn M., Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M., O’Meara, Matthew J., Rezelj, Veronica V., Guo, Jeffrey Z., Swaney, Danielle L., Tummino, Tia A., Kaake, Robyn M., Richards, Alicia L., Tutuncuoglu, Beril, Foussard, Helene, Haas, Kelsey, Modak, Maya, Haas, Paige, Braberg, Hannes, Fabius, Jacqueline M., Eckhardt, Manon, Bennett, Melanie J., Cakir, Merve, McGregor, Michael J., Li, Qiongyu, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T., Melnyk, James E., Chorba, John S., Lou, Kevin, Dai, Shizhong A., Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Perica, Tina, Ganesan, Sai J., Saltzberg, Daniel J., Calviello, Lorenzo, Venkataramanan, Srivats, Lin, Yizhu, Liu, YongFeng, Wankowicz, Stephanie A., Bohn, Markus, Safari, Maliheh, Ugur, Fatima S., Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Fletcher, Sabrina J., Cai, Yiming, Chang, Jason C. J., Broadhurst, David J., Klippsten, Saker, Sharp, Phillip P., Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Cavero, Devin A., Hiatt, Joseph, Roth, Theodore L., Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M., Frankel, Alan D., Verba, Kliment A., Agard, David A., Emerman, Michael, Jura, Natalia, von Zastrow, Mark, Verdin, Eric, Ashworth, Alan, Schwartz, Olivier, Mukherjee, Shaeri, Jacobson, Matt, Fujimori, Danica G., Ideker, Trey, Craik, Charles S., Floor, Stephen N., Fraser, James S., Gross, John D., Roth, Bryan L., Ruggero, Davide, Taunton, Jack, Beltrao, Pedro, Vignuzzi, Marco, Shokat, Kevan M., Shoichet, Brian K., Krogan, Nevan J.

“…A newly described coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the causative agent of coronavirus disease 2019…”
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Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient by Jiménez-Sánchez, Alejandro, Memon, Danish, Pourpe, Stephane, Veeraraghavan, Harini, Li, Yanyun, Vargas, Hebert Alberto, Gill, Michael B., Park, Kay J., Zivanovic, Oliver, Konner, Jason, Ricca, Jacob, Zamarin, Dmitriy, Walther, Tyler, Aghajanian, Carol, Wolchok, Jedd D., Sala, Evis, Merghoub, Taha, Snyder, Alexandra, Miller, Martin L.

“…We present an exceptional case of a patient with high-grade serous ovarian cancer, treated with multiple chemotherapy regimens, who exhibited regression of…”
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