Search Results - "Melvold, RW"

Sex-Specific Quantitative Trait Loci Govern Susceptibility to Theiler's Murine Encephalomyelitis Virus-Induced Demyelination by Butterfield, Russell J, Roper, Randall J, Rhein, Dominic M, Melvold, Roger W, Haynes, Lia, Ma, Runlin Z, Doerge, R. W, Teuscher, Cory

“…Susceptibility to Theiler's murine encephalomyelitis virus-induced demyelination (TMEVD), a mouse model for multiple sclerosis (MS), is genetically controlled…”
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Theiler's Murine Encephalomyelitis Virus (TMEV)-Induced Demyelination: A Model for Human Multiple Sclerosis by Dal Canto, Mauro C., Kim, Byung S., Miller, Stephen D., Melvold, Roger W.

“…Numerous studies suggest that a viral infection, on the appropriate genetic background, may play an important pathogenetic role in the development of multiple…”
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Susceptibility to Theiler’s murine encephalomyelitis virus-induced demyelinating disease in BALB/cAnNCr mice is related to absence of a CD4+ T-cell subset by Karls, K A, Denton, P W, Melvold, R W

“…Two histocompatible substrains of BALB/c mice (BALB/cByJ, BALB/cAnNCr) are resistant and susceptible, respectively, to Theiler’s murine encephalomyelitis…”
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CD8+ T cells reduce in vitro interferon-γ production in Theiler's murine encephalomyelitis virus-induced demyelinating disease model by DENTON, Paul W, TELLO, Christina M, MELVOLD, Roger W

“…In the Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease model for multiple sclerosis, regulatory CD8+ T cells prevent…”
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CD8 + T cells from Theiler’s virus-resistant BALB/cByJ mice downregulate pathogenic virus-specific CD4 + T cells by Haynes, Lia M, Vanderlugt, Carol L, Dal Canto, Mauro C, Melvold, Roger W, Miller, Stephen D

“…Theiler’s murine encephalomyelitis virus (TMEV) is a picornavirus which induces an immune-mediated demyelinating disease in susceptible strains of mice and…”
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Evidence that Tmevd2 and eae3 may represent either a common locus or members of a gene complex controlling susceptibility to immunologically mediated demyelination in mice by Teuscher, C, Rhein, DM, Livingstone, KD, Paynter, RA, Doerge, RW, Nicholson, SM, Melvold, RW

“…Theiler's murine encephalomyelitis virus (TMEV)-induced demyelination and experimental allergic encephalomyelitis are the principal immunologically mediated,…”
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Prolonged Hya-disparate skin graft survival in ethanol-consuming mice : Correlation with impaired delayed hypersensitivity by KEGIANG WANG, BUSKER-MANNIE, Ann E, HOEFT, Jennifer, VASQUEZ, Kristine, MILLER, Stephen D, MELVOLD, Roger W, WALTENBAUGH, Carl

“…Ethanol consumption impairs cell-mediated immunity and enhances humoral immunity. Among cell-mediated immune reactions, little is known of the effect of…”
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Adoptively transferred CD8+ T lymphocytes provide protection against TMEV-induced demyelinating disease in BALB/c mice by Nicholson, SM, Dal Canto, MC, Miller, SD, Melvold, RW

“…On intracerebral infection with the BeAn strain of Theiler's murine encephalomyelitis virus (TMEV), certain mouse strains develop a chronic demyelinating…”
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The role of protective CD8 + T cells in resistance of BALB/c mice to Theiler's murine encephalomyelitis virus-induced demyelinating disease: regulatory vs. lytic by Nicholson, Simone M, Haynes, Lia M, Vanderlugt, Carol L, Miller, Stephen D, Melvold, Roger W

“…Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease (TMEV-IDD) is an excellent model for human multiple sclerosis. Within the BALB/c…”
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Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV- specific delayed-type hypersensitivity by Clatch, RJ, Melvold, RW, Miller, SD, Lipton, HL

“…Intracranial inoculation of Theiler's murine encephalomyelitis virus (TMEV) leads to the development of a chronic demyelinating disorder in certain mouse…”
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A Complex Major Histocompatibility Complex D Locus Variant Generated by an Unusual Recombination Mechanism in Mice by Yun, Theodore J., Melvold, Roger W., Pease, Larry R.

“…A spontaneous variant of the mouse class I major histocompatibility complex Db gene, designated Dbm28, is characterized. This mutation consists of a cluster of…”
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BALB/c substrain differences in susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease by Nicholson, S M, Peterson, J D, Miller, S D, Wang, K, Dal Canto, M C, Melvold, R W

“…We report differences among BALB/c substrains in susceptibility to Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease, an…”
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Variations in genetic control of susceptibility to Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Differences between susceptible SJL/J and resistant BALB/c strains map near the T cell beta-chain constant gene on chromosome 6 by Melvold, RW, Jokinen, DM, Knobler, RL, Lipton, HL

“…In some susceptible mouse strains, intracerebral (IC) inoculation of Theiler's murine encephalomyelitis virus (TMEV) results in a persistent infection leading…”
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Histocompatibility gene mutation rates in the mouse: a 25-year review by Melvold, R W, Wang, K, Kohn, H I

“…Mutation rates of H2 and non-H2 histocompatibility genes in the mouse are examined over a 25-year period. Detected by skin graft rejections, the mutations were…”
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Hierarchy of effects of the MHC and T cell receptor beta-chain genes in susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease by Kappel, CA, Dal Canto, MC, Melvold, RW, Kim, BS

“…Intracerebral inoculation of susceptible mice with Theiler's murine encephalomyelitis virus induces a demyelinating disease that is similar to human multiple…”
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Recognition of a single amino acid change on the surface of a major transplantation antigen is in the context of self peptide by Pullen, JK, Tallquist, MD, Melvold, RW, Pease, LR

“…The transcripts encoding two strongly alloantigenic class I mutant molecules, Kdm4 and Kdm5, were characterized and found to encode products that differ from…”
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Ir gene function in an I-A subregion mutant B6.C-H-2bm12 by Michaelides, M, Sandrin, M, Morgan, G, McKenzie, I F, Ashman, R, Melvold, R W

“…The B6.C-H2bm12 (bm 12) strain has a mutation in the I-A subregion of the murine H-2 complex and is characterized by a loss of serologically detected Ia…”
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A hybrid between a resistant and a susceptible strain of mouse alters the pattern of Theiler's murine encephalomyelitis virus-induced white matter disease and favors oligodendrocyte-mediated remyelination by Dal Canto, M C, Melvold, R W, Kim, B S

“…Theiler's murine encephalomyelitis virus (TMEV) produces a chronic disease in its natural host, the mouse, characterised by primary inflammatory demyelination…”
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Mutation at I-A beta chain prevents experimental autoimmune myasthenia gravis by CHRISTADOSS, P, LINDSTROM, J. M, MELVOLD, R. W, TALAL, N

“…Immune response (Ir) gene(s) at the I-A subregion of the mouse H-2 complex influence susceptibility to experimental autoimmune myasthenia gravis (EAMG). To…”
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Genetic analysis of susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease in the SWR strain by Nicholson, Simone M., Jokinen, Diane M., Dal Canto, Mauro C, Kim, Byung S., Melvold, Roger W.

“…SWR/J mice are susceptible to immune-mediated central (CNS) demyelination following infection by Theiler's murine encephalomyelitis virus (TMEV). SWR/J…”
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