Search Results - "Meltzer, S J"
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Long non-coding antisense RNA KRT7-AS is activated in gastric cancers and supports cancer cell progression by increasing KRT7 expression
Published in Oncogene (15-09-2016)“…Alterations in long non-coding RNAs (lncRNAs) are associated with human carcinogenesis. One group of lncRNAs, which are antisense in orientation to coding…”
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MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro
Published in Oncogene (31-03-2011)“…The dismal outcome of gastric cancer patients highlights the need for diagnostic biomarkers and effective therapeutic targets, such as microRNAs. We sought to…”
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Gestational diabetes mellitus screening and diagnosis: a prospective randomised controlled trial comparing costs of one‐step and two‐step methods
Published in BJOG : an international journal of obstetrics and gynaecology (01-03-2010)“…Please cite this paper as: Meltzer S, Snyder J, Penrod J, Nudi M, Morin L. Gestational diabetes mellitus screening and diagnosis: a prospective randomised…”
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Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma
Published in Oncogene (20-09-2007)“…The nel-like1 (NELL1) gene maps to chromosome 11p15, which frequently undergoes loss of heterozygosity in esophageal adenocarcinoma (EAC). NELL1 promoter…”
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Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis
Published in Gastroenterology (New York, N.Y. 1943) (01-06-1999)“…Background & Aims: Inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 are important regulators of mucosal inflammation and epithelial cell…”
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Transcriptional profiling suggests that Barrett's metaplasia is an early intermediate stage in esophageal adenocarcinogenesis
Published in Oncogene (01-06-2006)“…To investigate the relationship between Barrett's esophagus (BE) and esophageal adenocarcinoma (EAC), we determined gene expression profiles of discrete…”
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Analysis of Adenomatous polyposis coli promoter hypermethylation in human cancer
Published in Cancer research (Chicago, Ill.) (15-08-2000)“…Germ-line mutations in the tumor suppressor gene APC are associated with hereditary familial adenomatous polyposis (FAP), and somatic mutations are common in…”
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Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas
Published in Cancer research (Chicago, Ill.) (15-07-1998)“…Barrett's esophagus is a premalignant condition arising in response to chronic reflux esophagitis. Inducible nitric oxide synthase (iNOS; NOS-2) and…”
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Global gene expression profiling in Barrett's esophagus and esophageal cancer: a comparative analysis using cDNA microarrays
Published in Oncogene (17-01-2002)“…In order to identify and contrast global gene expression profiles defining the premalignant syndrome, Barrett's esophagus, as well as frank esophageal cancer,…”
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Molecular Evolution of the Metaplasia-Dysplasia-Adenocarcinoma Sequence in the Esophagus
Published in The American journal of pathology (01-04-1999)“…The incidence of adenocarcinoma of the esophagus has been increasing in developing countries over the last three decades and probably reflects a genuine…”
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E-Cadherin Gene Promoter Hypermethylation in Primary Human Gastric Carcinomas
Published in JNCI : Journal of the National Cancer Institute (05-04-2000)“…Background: E (epithelial)-cadherin, the cell adhesion molecule also considered a potential invasion/metastasis suppressor, is mutationally inactivated in…”
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12
Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line
Published in Gastroenterology (New York, N.Y. 1943) (01-12-1996)“…BACKGROUND & AIMS: Helicobacter pylori uniquely colonizes the human stomach and produces gastric mucosal inflammation. High-output nitric oxide production by…”
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Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways
Published in Journal of clinical pathology (01-06-1999)“…BACKGROUND: 10% of sporadic colorectal cancers are characterised by a low level of microsatellite instability (MSI-L). These are not thought to differ…”
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Hypermethylation of the hMLH1 gene promoter in human gastric cancers with microsatellite instability
Published in Cancer research (Chicago, Ill.) (01-03-1999)“…Human gastric carcinoma shows a higher prevalence of microsatellite instability (MSI) than does any other type of sporadic human cancer. The reasons for this…”
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Microsatellite instability occurs frequently in human gastric carcinoma
Published in Oncogene (01-01-1994)“…Microsatellites are short repeated oligonucleotide sequences found throughout the human genome. Microsatellite instability has been reported in hereditary and…”
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Allelotype analysis of oesophageal adenocarcinoma: loss of heterozygosity occurs at multiple sites
Published in British journal of cancer (01-10-1998)“…Deletions of tumour-suppressor genes can be detected by loss of heterozygosity (LOH) studies, which were performed on 23 cases of adenocarcinoma of the…”
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Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia
Published in Oncogene (27-07-2000)“…The adenomatous polyposis coli (APC) tumor suppressor gene is mutationally inactivated in both familial and sporadic forms of colorectal cancers. In addition,…”
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Following in mother's footsteps? Mother-daughter risks for insulin resistance and cardiovascular disease 15 years after gestational diabetes
Published in Diabetic medicine (01-03-2010)“…Diabet. Med. 27, 257–265 (2010) Aims To determine effects on mothers and daughters of gestational diabetes mellitus/gestational impaired glucose tolerance…”
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PTEN1 is frequently mutated in primary endometrial carcinomas
Published in Nature genetics (01-10-1997)“…Endometrial cancer is the most common cancer of the female genital tract in America and Japan. However, our knowledge regarding the molecular mechanisms…”
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ABC Of Colorectal Cancer: Molecular Basis For Risk Factors
Published in BMJ (Online) (07-10-2000)Get full text
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