Search Results - "Meltzer, C C"

Ethical considerations in artificial intelligence by Safdar, Nabile M., Banja, John D., Meltzer, Carolyn C.

“…•As in the case of most disruptive technologies, assessment of and consensus on the possible ethical pitfalls lag.•selection bias in AI datasets can result in…”
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APOE4 derived from astrocytes leads to blood-brain barrier impairment by Jackson, Rosemary J, Meltzer, Jonah C, Nguyen, Huong, Commins, Caitlin, Bennett, Rachel E, Hudry, Eloise, Hyman, Bradley T

“…Apolipoprotein E (ApoE) is a multifaceted secreted molecule synthesized in the CNS by astrocytes and microglia, and in the periphery largely by the liver. ApoE…”
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Pathological correlations of [F‐18]‐AV‐1451 imaging in non‐alzheimer tauopathies by Marquié, Marta, Normandin, Marc D., Meltzer, Avery C., Siao Tick Chong, Michael, Andrea, Nicolas V., Antón‐Fernández, Alejandro, Klunk, William E., Mathis, Chester A., Ikonomovic, Milos D., Debnath, Manik, Bien, Elizabeth A., Vanderburg, Charles R., Costantino, Isabel, Makaretz, Sara, DeVos, Sarah L., Oakley, Derek H., Gomperts, Stephen N., Growdon, John H., Domoto‐Reilly, Kimiko, Lucente, Diane, Dickerson, Bradford C., Frosch, Matthew P., Hyman, Bradley T., Johnson, Keith A., Gómez‐Isla, Teresa

“…Objective Recent studies have shown that positron emission tomography (PET) tracer AV‐1451 exhibits high binding affinity for paired helical filament (PHF)‐tau…”
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Capacity for 5-HT1A-mediated autoregulation predicts amygdala reactivity by Fisher, P M, Meltzer, C C, Ziolko, S K, Price, J C, Moses-Kolko, E L, Berga, S L, Hariri, A R

“…We examined the contribution of 5-HT1A autoreceptors (with [11C]WAY100635 positron emission tomography) to amygdala reactivity (with blood oxygenation…”
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Distinct cytokine profiles in human brains resilient to Alzheimer's pathology by Barroeta-Espar, Isabel, Weinstock, Laura D., Perez-Nievas, Beatriz G., Meltzer, Avery C., Siao Tick Chong, Michael, Amaral, Ana C., Murray, Melissa E., Moulder, Krista L., Morris, John C., Cairns, Nigel J., Parisi, Joseph E., Lowe, Val J., Petersen, Ronald C., Kofler, Julia, Ikonomovic, Milos D., López, Oscar, Klunk, William E., Mayeux, Richard P., Frosch, Matthew P., Wood, Levi B., Gomez-Isla, Teresa

“…Our group has previously studied the brains of some unique individuals who are able to tolerate robust amounts of Alzheimer's pathological lesions (amyloid…”
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Increased Dopamine D2/D3 Receptor Binding After Recovery from Anorexia Nervosa Measured by Positron Emission Tomography and [ 11C]Raclopride by Frank, Guido K., Bailer, Ursula F., Henry, Shannan E., Drevets, Wayne, Meltzer, Carolyn C., Price, Julie C., Mathis, Chester A., Wagner, Angela, Hoge, Jessica, Ziolko, Scott, Barbarich-Marsteller, Nicole, Weissfeld, Lisa, Kaye, Walter H.

“…Several lines of evidence support the possibility that disturbances of dopamine (DA) function could contribute to alterations of weight, feeding, motor…”
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1-(4-Methylphenyl)-2-pyrrolidin-1-yl-pentan-1-one (Pyrovalerone) Analogues:  A Promising Class of Monoamine Uptake Inhibitors by Meltzer, Peter C, Butler, David, Deschamps, Jeffrey R, Madras, Bertha K

“…Dopamine, serotonin, and norepinephrine are essential for neurotransmission in the mammalian system. These three neurotransmitters have been the focus of…”
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Publisher Correction: Diagnostic accuracy of novel mRNA blood biomarkers of infection to predict outcomes in emergency department patients with undifferentiated abdominal pain by Meltzer, Andrew C., Wargowsky, Richard S., Moran, Seamus, Jordan, Tristan, Toma, Ian, Jepson, Tisha, Shu, Shiyu, Ma, Yan, McCaffrey, Timothy A.

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Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B by Price, Julie C, Klunk, William E, Lopresti, Brian J, Lu, Xueling, Hoge, Jessica A, Ziolko, Scott K, Holt, Daniel P, Meltzer, Carolyn C, DeKosky, Steven T, Mathis, Chester A

“…A valid quantitative imaging method for the measurement of amyloid deposition in humans could improve Alzheimer's disease (AD) diagnosis and antiamyloid…”
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Diagnostic accuracy of novel mRNA blood biomarkers of infection to predict outcomes in emergency department patients with undifferentiated abdominal pain by Meltzer, Andrew C., Wargowsky, Richard S., Moran, Seamus, Jordan, Tristan, Toma, Ian, Jepson, Tisha, Shu, Shiyu, Ma, Yan, McCaffrey, Timothy A.

“…Abdominal pain represents greater than 20% of US Emergency Department (ED) visits due to a wide range of illnesses. There are currently no reliable blood…”
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Selection of an Efficient AAV Vector for Robust CNS Transgene Expression by Hanlon, Killian S., Meltzer, Jonah C., Buzhdygan, Tetyana, Cheng, Ming J., Sena-Esteves, Miguel, Bennett, Rachel E., Sullivan, Timothy P., Razmpour, Roshanak, Gong, Yi, Ng, Carrie, Nammour, Josette, Maiz, Daniela, Dujardin, Simon, Ramirez, Servio H., Hudry, Eloise, Maguire, Casey A.

“…Adeno-associated virus (AAV) capsid libraries have generated improved transgene delivery vectors. We designed an AAV library construct, iTransduce, that…”
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Serotonin alterations in anorexia and bulimia nervosa: New insights from imaging studies by Kaye, Walter H., Frank, Guido K., Bailer, Ursula F., Henry, Shannan E., Meltzer, Carolyn C., Price, Julie C., Mathis, Chester A., Wagner, Angela

“…Anorexia nervosa (AN) and bulimia nervosa (BN) are related disorders with relatively homogenous presentations such as age of onset and gender distribution. In…”
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Alterations in Cortical Thickness and White Matter Integrity in Mild Cognitive Impairment Measured by Whole-Brain Cortical Thickness Mapping and Diffusion Tensor Imaging by Wang, L, Goldstein, F.C, Veledar, E, Levey, A.I, Lah, J.J, Meltzer, C.C, Holder, C.A, Mao, H

“…Mild cognitive impairment (MCI) is a risk factor for Alzheimer disease and can be difficult to diagnose because of the subtlety of symptoms. This study…”
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Imaging recommendations for acute stroke and transient ischemic attack patients: A joint statement by the American Society of Neuroradiology, the American College of Radiology, and the Society of NeuroInterventional Surgery by Wintermark, M, Sanelli, P C, Albers, G W, Bello, J, Derdeyn, C, Hetts, S W, Johnson, M H, Kidwell, C, Lev, M H, Liebeskind, D S, Rowley, H, Schaefer, P W, Sunshine, J L, Zaharchuk, G, Meltzer, C C

“…Stroke is a leading cause of death and disability worldwide. Imaging plays a critical role in evaluating patients suspected of acute stroke and transient…”
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Head and neck malignancy: is PET/CT more accurate than PET or CT alone? by Branstetter, 4th, Barton F, Blodgett, Todd M, Zimmer, Lee A, Snyderman, Carl H, Johnson, Jonas T, Raman, Subha, Meltzer, Carolyn C

“…To prospectively determine whether combined positron emission tomography (PET) and computed tomography (CT) is more accurate than either PET or CT alone in…”
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Summary of the Affordable Care Act by MELTZER, C. C

“…The voluminous bill known as the PPACA of 2010 enabled substantial changes to our health care delivery system, some of which remain to be enacted for several…”
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Lessons learned about [F-18]-AV-1451 off-target binding from an autopsy-confirmed Parkinson's case by Marquié, Marta, Verwer, Eline E, Meltzer, Avery C, Kim, Sally Ji Who, Agüero, Cinthya, Gonzalez, Jose, Makaretz, Sara J, Siao Tick Chong, Michael, Ramanan, Prianca, Amaral, Ana C, Normandin, Marc D, Vanderburg, Charles R, Gomperts, Stephen N, Johnson, Keith A, Frosch, Matthew P, Gómez-Isla, Teresa

“…[F-18]-AV-1451 is a novel positron emission tomography (PET) tracer with high affinity to neurofibrillary tau pathology in Alzheimer's disease (AD). PET…”
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Reduced cerebral blood flow response and compensation among patients with untreated hypertension by JENNINGS, J. R, MULDOON, M. F, RYAN, C, PRICE, J. C, GREER, P, SUTTON-TYRRELL, K, VAN DER VEEN, F. M, MELTZER, C. C

“…To determine whether memory performance in hypertensive subjects induces diminished parietal and prefrontal blood flow activation relative to normotensive…”
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Simplified Quantification of Pittsburgh Compound B Amyloid Imaging PET Studies: A Comparative Analysis by Lopresti, Brian J, Klunk, William E, Mathis, Chester A, Hoge, Jessica A, Ziolko, Scott K, Lu, Xueling, Meltzer, Carolyn C, Schimmel, Kurt, Tsopelas, Nicholas D, DeKosky, Steven T, Price, Julie C

“…PET studies have been performed using the amyloid binding radiotracer Pittsburgh Compound B (PIB). Previous quantitative analyses using arterial blood showed…”
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Women Rising to the Top: The Tipping Point for the ASNR by Meltzer, C C, Sanelli, P C, Hepp, M B, Bello, J A

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