Search Results - "Mels, Catharina M.C."

A urinary peptidomics approach for early stages of cardiovascular disease risk: The African-PREDICT study by de Beer, Dalene, Mels, Catharina M C, Schutte, Aletta E, Delles, Christian, Mary, Sheon, Mullen, William, Mischak, Harald, Kruger, Ruan

“…Cardiovascular disease (CVD) affects individuals across the lifespan, with multiple cardiovascular (CV) risk factors increasingly present in young populations…”
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Blood pressure and nitric oxide synthesis capacity in physically active and inactive groups: the SABPA study by van Niekerk, Elandi, Botha Le Roux, Shani, Atzler, Dorothee, Schwedhelm, Edzard, Böger, Rainer H., van Rooyen, Johannes M., Moss, Sarah J., Mels, Catharina M. C.

“…Physical activity affects the vasculature through mechanisms related to nitric oxide bioavailability, oxidative stress, and inflammation; with endothelial…”
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Antioxidant enzyme activity is associated with blood pressure and carotid intima media thickness in black men and women: The SABPA study by van Zyl, Caitlynd, Huisman, Hugo W, Mels, Catharina M.C

“…Abstract In the urbanized black population of South Africa, oxidative stress may play a crucial role in the development of hypertension. Since oxidative stress…”
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Three-year change in oxidative stress markers is linked to target organ damage in black and white men: the SABPA study by Myburgh, Caitlynd, Huisman, Hugo W, M C Mels, Catharina

“…Oxidative stress is implicated in hypertension, carotid wall thickening, and renal dysfunction. Oxidative stress is linked to cardiovascular pathology in the…”
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Urinary albumin-to-creatinine ratio is inversely related to nitric oxide synthesis in young black adults: the African-PREDICT study by Craig, Ashleigh, Mels, Catharina M C, Schutte, Aletta E, Bollenbach, Alexander, Tsikas, Dimitrios, Schwedhelm, Edzard, Kruger, Ruan

“…Hypertension is common in black populations and is known to be associated with low nitric oxide (NO) bioavailability. We compared plasma and urinary NO-related…”
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Urinary metabolomics profiling by cardiovascular risk factors in young adults: the African Prospective study on Early Detection and Identification of Cardiovascular disease and Hypertension study by du Toit, Wessel L., Kruger, Ruan, Gafane-Matemane, Lebo F., Schutte, Aletta E., Louw, Roan, Mels, Catharina M.C.

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Identifying a urinary peptidomics profile for hypertension in young adults: The African‐PREDICT study by De Beer, Dalene, Mels, Catharina M.C., Schutte, Aletta E., Delles, Christian, Mary, Sheon, Mullen, William, Latosinska, Agnieszka, Mischak, Harald, Kruger, Ruan

“…Hypertension is one of the most important and complex risk factors for cardiovascular diseases (CVDs). By using urinary peptidomics analyses, we aimed to…”
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Twenty-four-hour ambulatory, but not clinic blood pressure associates with leptin in young adults with overweight or obesity: The African-PREDICT study by van Niekerk, Elandi, Botha-Le Roux, Shani, Mels, Catharina M C, Swanepoel, Mariette, Delles, Christian, Welsh, Paul, Kruger, Ruan

“…Hypertension and obesity are known pro-inflammatory conditions, and limited studies explored various blood pressure modalities and inflammatory markers in…”
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Identifying a urinary peptidomics profile for hypertension in young adults: The African‐PREDICT study: Urinary peptidomics and hypertension by De Beer, Dalene, Mels, Catharina M.C., Schutte, Aletta E., Delles, Christian, Mary, Sheon, Mullen, William, Latosinska, Agnieszka, Mischak, Harald, Kruger, Ruan

“…Abstract Hypertension is one of the most important and complex risk factors for cardiovascular diseases (CVDs). By using urinary peptidomics analyses, we aimed…”
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Urinary metabolomics profiling by cardiovascular risk factors in young adults: the African Prospective study on Early Detection and Identification of Cardiovascular disease and Hypertension study by du Toit, Wessel L., Kruger, Ruan, Gafane-Matemane, Lebo F., Schutte, Aletta E., Louw, Roan, Mels, Catharina M.C.

“…Risk factors contributes to a dysregulated metabolism and may ultimately increase the predisposition for cardiovascular disease (CVD) development. To increase…”
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Characterization of the Renin-Angiotensin-Aldosterone System in Young Healthy Black Adults: The African Prospective Study on the Early Detection and Identification of Hypertension and Cardiovascular Disease (African-PREDICT Study) by Gafane-Matemane, Lebo F., Kruger, Ruan, Smith, Wayne, Mels, Catharina M.C., Van Rooyen, Johannes M., Mokwatsi, Gontse G., Uys, Aletta S., Brits, Sanette J., Schutte, Aletta E.

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Exploring biomarkers associated with deteriorating vascular health using a targeted proteomics chip: The SABPA study by Dieden, Anna, Malan, Leone, Mels, Catharina M.C., Lammertyn, Leandi, Wentzel, Annemarie, Nilsson, Peter M., Gudmundsson, Petri, Jujic, Amra, Magnusson, Martin

“…In this observational study, by the use of a multiplex proteomic platform, we aimed to explore associations between 92 targeted proteins involved in…”
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Thiobarbituric acid-reactive substances relate to arterial stiffness and blood pressure in 6 to 8-year-old boys stratified by maternal risk by Craig, Ashleigh, Mels, Catharina M C, Kruger, Ruan

“…Early cardiovascular disease (CVD) onset can be inflicted by familial cardiovascular and lifestyle risk factors. We aimed to compare phenotypic characteristics…”
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The inflammatory score and cardiovascular risk in young adults with overweight or obesity: The African-PREDICT study by van Niekerk, Elandi, Mels, Catharina M.C., Swanepoel, Mariëtte, Delles, Christian, Welsh, Paul, Botha-Le Roux, Shani

“…[Display omitted] •Seemingly healthy young adults with excess adiposity may have higher health risks.•The inflammatory score is a comprehensive marker of…”
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Markers of arterial stiffness and urinary metabolomics in young adults with early cardiovascular risk: the African-PREDICT study by du Toit, Wessel L., Kruger, Ruan, Gafane-Matemane, Lebo F., Schutte, Aletta E., Louw, Roan, Mels, Catharina M. C.

“…Introduction Increased exposure to risk factors in the young and healthy contributes to arterial changes, which may be accompanied by an altered metabolism…”
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Using urinary metabolomics to identify metabolic pathways linked to cardiac structural alterations in young adults: The African-PREDICT study by du Toit, Wessel L., Kruger, Ruan, Gafane-Matemane, Lebo F., Schutte, Aletta E., Louw, Roan, Mels, Catharina M.C.

“…Risk factor exposure from young ages was shown to contribute to cardiovascular events - cardiac hypertrophy, which may be accompanied by an altered metabolism…”
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The African Prospective study on the Early Detection and Identification of Cardiovascular disease and Hypertension (African-PREDICT): Design, recruitment and initial examination by Schutte, Aletta E, Gona, Philimon N, Delles, Christian, Uys, Aletta S, Burger, Adele, Mels, Catharina MC, Kruger, Ruan, Smith, Wayne, Fourie, Carla MT, Botha, Shani, Lammertyn, Leandi, van Rooyen, Johannes M, Gafane-Matemane, Lebo F, Mokwatsi, Gontse G, Breet, Yolandi, Kruger, H Salome, Zyl, Tertia van, Pieters, Marlien, Zandberg, Lizelle, Louw, Roan, Moss, Sarah J, Khumalo, Itumeleng P, Huisman, Hugo W

“…Background Globally hypertension is stabilising, but in sub-Saharan Africa the incidence of hypertension remains on an increase. Although this might be…”
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Characterization of the Renin-Angiotensin-Aldosterone System in Young Healthy Black Adults: The African Prospective Study on the Early Detection and Identification of Hypertension and Cardiovascular Disease (African-PREDICT Study) by Gafane-Matemane, Lebo F., Kruger, Ruan, Smith, Wayne, Mels, Catharina M.C., Van Rooyen, Johannes M., Mokwatsi, Gontse G., Uys, Aletta S., Brits, Sanette J., Schutte, Aletta E.

“…[Figure: see text]…”
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High prevalence but lack of awareness of hypertension in South Africa, particularly among men and young adults by Woodiwiss, Angela J., Orchard, Ane, Mels, Catharina M. C., Uys, Aletta S., Nkeh-Chungag, Benedicta N., Kolkenbeck-Ruh, Andrea, Ware, Lisa J., Yates, Samantha, Jones, Erika S. W., Peterson, Vernice R., Poulter, Neil R.

“…Abstract Cardiovascular disease (CVD) is a leading cause of death in South Africa (SA) and high blood pressure (BP) is the primary risk factor. However,…”
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Nitric oxide-related markers link inversely to blood pressure in black boys and men: the ASOS and African-PREDICT studies by Craig, Ashleigh, Mels, Catharina M. C., Schutte, Aletta E., Tsikas, Dimitrios, Kruger, Ruan

“…Nitric oxide plays an important role in maintaining endothelial function, while increased oxidative stress may lead to nitric oxide inactivation and…”
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