Search Results - "Melody, Kevin"

Establishment of an African green monkey model for COVID-19 and protection against re-infection by Woolsey, Courtney, Borisevich, Viktoriya, Prasad, Abhishek N., Agans, Krystle N., Deer, Daniel J., Dobias, Natalie S., Heymann, John C., Foster, Stephanie L., Levine, Corri B., Medina, Liana, Melody, Kevin, Geisbert, Joan B., Fenton, Karla A., Geisbert, Thomas W., Cross, Robert W.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for an unprecedented global pandemic of COVID-19. Animal models are urgently needed…”
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Prior vaccination with rVSV-ZEBOV does not interfere with but improves efficacy of postexposure antibody treatment by Cross, Robert W., Bornholdt, Zachary A., Prasad, Abhishek N., Geisbert, Joan B., Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Melody, Kevin, Fenton, Karla A., Feldmann, Heinz, Sprecher, Armand, Zeitlin, Larry, Geisbert, Thomas W.

“…A replication-competent vesicular stomatitis virus vaccine expressing the Ebola virus (EBOV) glycoprotein (GP) (rVSV-ZEBOV) was successfully used during the…”
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Moving beyond the mousetrap: current and emerging humanized mouse and rat models for investigating prevention and cure strategies against HIV infection and associated pathologies by Agarwal, Yash, Beatty, Cole, Biradar, Shivkumar, Castronova, Isabella, Ho, Sara, Melody, Kevin, Bility, Moses Turkle

“…The development of safe and effective combination antiretroviral therapies for human immunodeficiency virus (HIV) infection over the past several decades has…”
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Rilpivirine and Doravirine Have Complementary Efficacies Against NNRTI-Resistant HIV-1 Mutants by Smith, Steven J, Pauly, Gary T, Akram, Aamir, Melody, Kevin, Ambrose, Zandrea, Schneider, Joel P, Hughes, Stephen H

“…BACKGROUND:Rilpivirine (RPV) is the latest non-nucleoside reverse transcriptase inhibitor (NNRTI) to be approved by Food and Drug Administration to combat…”
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Establishment of an African green monkey model for COVID-19 and protection against reinfection by Woolsey, Courtney, Borisevich, Viktoriya, Prasad, Abhishek N., Agans, Krystle N., Deer, Daniel J., Dobias, Natalie S., Heymann, John C., Foster, Stephanie L., Levine, Corri B., Medina, Liana, Melody, Kevin, Geisbert, Joan B., Fenton, Karla A., Geisbert, Thomas W., Cross, Robert W.

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for an unprecedented global pandemic of COVID-19. Animal models are urgently needed…”
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Long-Acting Rilpivirine (RPV) Preexposure Prophylaxis Does Not Inhibit Vaginal Transmission of RPV-Resistant HIV-1 or Select for High-Frequency Drug Resistance in Humanized Mice by Melody, Kevin, Roy, Chandra N, Kline, Christopher, Cottrell, Mackenzie L, Evans, Dwayne, Shutt, Kathleen, Pennings, Pleuni S, Keele, Brandon F, Bility, Moses, Kashuba, Angela D M, Ambrose, Zandrea

“…As a long-acting formulation of the nonnucleoside reverse transcriptase inhibitor rilpivirine (RPV LA) has been proposed for use as preexposure prophylaxis…”
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Two Coselected Distal Mutations in HIV-1 Reverse Transcriptase (RT) Alter Susceptibility to Nonnucleoside RT Inhibitors and Nucleoside Analogs by Boyer, Paul L, Melody, Kevin, Smith, Steven J, Dunn, Linda L, Kline, Chris, Fischer, Douglas K, Dwivedi, Richa, Clark, Pat, Hughes, Stephen H, Ambrose, Zandrea

“…Two mutations, G112D and M230I, were selected in the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) by a novel nonnucleoside reverse…”
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Low Frequency of Drug-Resistant Variants Selected by Long-Acting Rilpivirine in Macaques Infected with Simian Immunodeficiency Virus Containing HIV-1 Reverse Transcriptase by Melody, Kevin, McBeth, Sarah, Kline, Christopher, Kashuba, Angela D M, Mellors, John W, Ambrose, Zandrea

“…Preexposure prophylaxis (PrEP) using antiretroviral drugs is effective in reducing the risk of human immunodeficiency virus type 1 (HIV-1) infection, but…”
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Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutants by Smith, Steven J, Pauly, Gary T, Akram, Aamir, Melody, Kevin, Rai, Ganesha, Maloney, David J, Ambrose, Zandrea, Thomas, Craig J, Schneider, Joel T, Hughes, Stephen H

“…Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are a class of antiretroviral compounds that bind in an allosteric binding pocket in HIV-1 RT, located…”
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HIV-1 Resistance to Rilpivirine in the Context of Pre-Exposure Prophylaxis by Melody, Kevin Patrick

“…To prevent further incidences of human immunodeficiency virus type 1 (HIV-1), pre-exposure prophylaxis (PrEP) is effective at inhibiting infection in high-risk…”
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Human immunodeficiency virus infection induces lymphoid fibrosis in the BM-liver-thymus-spleen humanized mouse model by Samal, Jasmine, Kelly, Samantha, Na-Shatal, Ali, Elhakiem, Abdallah, Das, Antu, Ding, Ming, Sanyal, Anwesha, Gupta, Phalguni, Melody, Kevin, Roland, Brad, Ahmed, Watfa, Zakir, Aala, Bility, Moses

“…A major pathogenic feature associated with HIV infection is lymphoid fibrosis, which persists during antiretroviral therapy (ART). Lymphoid tissues play…”
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Effectiveness of icing as a postharvest treatment for control of Vibrio vulnificus and Vibrio parahaemolyticus in the eastern oyster (Crassostrea virginica) by Melody, Kevin, Senevirathne, Reshani, Janes, Marlene, Jaykus, Lee Ann, Supan, John

“…The focus of this research was to investigate the efficacy of icing as a postharvest treatment for reduction of the levels of Vibrio vulnificus and Vibrio…”
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Human immunodeficiency virus infection induces lymphoid fibrosis in the BM-liver-thymus-spleen humanized mouse model by Samal, Jasmine, Kelly, Samantha, Na-Shatal, Ali, Elhakiem, Abdallah, Das, Antu, Ding, Ming, Sanyal, Anwesha, Gupta, Phalguni, Melody, Kevin, Roland, Brad, Ahmed, Watfa, Zakir, Aala, Bility, Moses

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Two Post-Harvest Treatments for the Reduction of Vibrio Vulnificus and Vibrio Parahaemolyticus in Eastern Oysters (Crassostrea Virginica) by Melody, Kevin Patrick

“…Vibrio vulnificus and V. parahaemolyticus are naturally occurring estuarine bacteria and the leading causes of seafood-borne illness in the United States…”
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