Search Results - "Melo Resende, Daniela"

Synthesis, Design, and Structure‐Activity Relationship of a Benzenesulfonylpiperazine Series against Trypanosoma cruzi by Cassiano Martinho, Ana Clara, Melo Resende, Daniela, Landin, Emanuelly Silva, Dit Lapierre, Thibault Joseph William Jacques, Bernardes, Talita Cristina Diniz, Martins, Luan Carvalho, Ferreira, Rafaela Salgado, Murta, Silvane Maria Fonseca, Oliveira Rezende Júnior, Celso

“…Chagas disease is a neglected tropical disease, endemic in Latin America and caused by the protozoan parasite Trypanosoma cruzi. Available treatments show low…”
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Evaluation and discovery of novel benzothiazole derivatives as promising hits against Leishmania infantum by Lapierre, Thibault Joseph William Jacques Dit, Farago, Danilo Nascimento, de Moura Lodi Cruz, Mariza Gabriela Faleiro, de Melo Resende, Daniela, de Oliveira, Adriane Cristina Rosa, Dos Santos, Brenda Rosa Macedo, de Oliveira Souza, Felipe, Michelan-Duarte, Simone, Chelucci, Rafael C, Andricopulo, Adriano D, Ferreira, Leonardo L G, Pilau, Eduardo Jorge, Murta, Silvane Maria Fonseca, de Oliveira Rezende Júnior, Celso

“…An early exploration of the benzothiazole class against two kinetoplastid parasites, Leishmania infantum and Trypanosoma cruzi, has been performed after the…”
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Expression Profile of Genes Related to the Th17 Pathway in Macrophages Infected by Leishmania major and Leishmania amazonensis: The Use of Gene Regulatory Networks in Modeling This Pathway by Gonçalves, Leilane Oliveira, Pulido, Andrés F. Vallejo, Mathias, Fernando Augusto Siqueira, Enes, Alexandre Estevão Silvério, Carvalho, Maria Gabriela Reis, de Melo Resende, Daniela, Polak, Marta E., Ruiz, Jeronimo C.

“…Leishmania amazonensis and Leishmania major are the causative agents of cutaneous and mucocutaneous diseases. The infections‘ outcome depends on host–parasite…”
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Optimization of benzenesulfonyl derivatives as anti-Trypanosomatidae agents: Structural design, synthesis, and pharmacological assessment against Trypanosoma cruzi and Leishmania infantum by Freitas de Lima Hercos, Guilherme, Gabriela Faleiro de Moura Lodi Cruz, Mariza, Clara Cassiano Martinho, Ana, de Melo Resende, Daniela, Farago Nascimento, Danilo, Derksen Macruz, Paula, Jorge Pilau, Eduardo, Maria Fonseca Murta, Silvane, de Oliveira Rezende Júnior, Celso

“…[Display omitted] Leishmaniasis and Chagas disease are neglected tropical diseases caused by Trypanosomatidae parasites. Given the numerous limitations…”
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A specific Leishmania infantum polyepitope vaccine triggers Th1-type immune response and protects against experimental visceral leishmaniasis by Lopes Valentim Di Paschoale Ostolin, Thais, Rodrigues Gusmão, Miriã, Augusto Siqueira Mathias, Fernando, Mirelle de Oliveira Cardoso, Jamille, Mendes Roatt, Bruno, Dian de Oliveira Aguiar-Soares, Rodrigo, Conceição Ruiz, Jeronimo, de Melo Resende, Daniela, Cristiane Fortes de Brito, Rory, Barbosa Reis, Alexandre

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Diversity and genome mapping assessment of disordered and functional domains in trypanosomatids by Avelar, Grace Santos Tavares, Gonçalves, Leilane Oliveira, Guimarães, Frederico Gonçalves, Guimarães, Paul Anderson Souza, do Nascimento Rocha, Luiz Gustavo, Carvalho, Maria Gabriela Reis, de Melo Resende, Daniela, Ruiz, Jeronimo Conceição

“…The proteins that have structural disorder exemplify a class of proteins which is part of a new frontier in structural biology that demands a new understanding…”
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Protective immunity against challenge with Leishmania ( Leishmania ) chagasi in beagle dogs vaccinated with recombinant A2 protein by Fernandes, Ana Paula, Costa, Míriam Maria Silva, Coelho, Eduardo Antônio Ferraz, Michalick, Marilene Suzan Marques, de Freitas, Eloísa, Melo, Maria Norma, Luiz Tafuri, Wagner, Resende, Daniela de Melo, Hermont, Vinícius, Abrantes, Christiane de Freitas, Gazzinelli, Ricardo Tostes

“…Abstract In this study, we investigated in dogs the immunogenicity and protective immunity against Leishmania ( Leishmania ) chagasi infection induced by…”
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Comparative transcriptomic analysis of antimony resistant and susceptible Leishmania infantum lines by Andrade, Juvana Moreira, Gonçalves, Leilane Oliveira, Liarte, Daniel Barbosa, Lima, Davi Alvarenga, Guimarães, Frederico Gonçalves, de Melo Resende, Daniela, Santi, Ana Maria Murta, de Oliveira, Luciana Marcia, Velloso, João Paulo Linhares, Delfino, Renato Guimarães, Pescher, Pascale, Späth, Gerald F, Ruiz, Jeronimo Conceição, Murta, Silvane Maria Fonseca, Velloso, Joao Paulo, Delfino, Renato Guimaraes, Spath, Gerald F, Ruiz, Jeronimo Conceicao

“…One of the major challenges to leishmaniasis treatment is the emergence of parasites resistant to antimony. To study differentially expressed genes associated…”
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In silico analysis of putative dormancy genes in Plasmodium vivax by de Souza Ribeiro, Ricardo, de Melo Resende, Daniela, Ruiz, Jerônimo Conceição, Ferreira Alves de Brito, Cristiana

“…[Display omitted] •Mauritanian I and North Korean are the highest diverse P. vivax genomes.•Selected putative dormancy genes are conserved and under purifying…”
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Molecular diagnosis of canine visceral leishmaniasis: A comparative study of three methods using skin and spleen from dogs with natural Leishmania infantum infection by Reis, Levi Eduardo Soares, Coura-Vital, Wendel, Roatt, Bruno Mendes, Bouillet, Leoneide Érica Maduro, Ker, Henrique Gama, Fortes de Brito, Rory Cristiane, Resende, Daniela de Melo, Carneiro, Mariângela, Giunchetti, Rodolfo Cordeiro, Marques, Marcos José, Carneiro, Cláudia Martins, Reis, Alexandre Barbosa

“…Polymerase chain reaction (PCR) and its variations represent highly sensitive and specific methods for Leishmania DNA detection and subsequent canine visceral…”
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Shotgun proteomics to unravel the complexity of the Leishmania infantum exoproteome and the relative abundance of its constituents by Braga, Micheline Soares, Neves, Leandro Xavier, Campos, Jonatan Marques, Roatt, Bruno Mendes, de Oliveira Aguiar Soares, Rodrigo Dian, Braga, Samuel Leôncio, de Melo Resende, Daniela, Reis, Alexandre Barbosa, Castro-Borges, William

“…•Molecular composition and relative abundance of the L. infantum exoproteome.•Nucleotide/phosphate metabolism and antioxidant activity dominate the…”
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A chimeric vaccine combined with adjuvant system induces immunogenicity and protection against visceral leishmaniasis in BALB/c mice by Ostolin, Thais Lopes Valentim Di Paschoale, Gusmão, Miriã Rodrigues, Mathias, Fernando Augusto Siqueira, Cardoso, Jamille Mirelle de Oliveira, Roatt, Bruno Mendes, Aguiar-Soares, Rodrigo Dian de Oliveira, Ruiz, Jeronimo Conceição, Resende, Daniela de Melo, de Brito, Rory Cristiane Fortes, Reis, Alexandre Barbosa

“…In Brazil, canine visceral leishmaniasis is an important public health problem due to its alarming growth. The high prevalence of infected dogs reinforces the…”
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Disruption of multiple copies of the Prostaglandin F2alpha synthase gene affects oxidative stress response and infectivity in Trypanosoma cruzi by Santi, Ana Maria Murta, Ribeiro, Juliana Martins, Reis-Cunha, João Luís, Burle-Caldas, Gabriela de Assis, Santos, Isabella Fernandes Martins, Silva, Paula Alves, Resende, Daniela de Melo, Bartholomeu, Daniella Castanheira, Teixeira, Santuza Maria Ribeiro, Murta, Silvane Maria Fonseca

“…Chagas disease, caused by the protozoan Trypanosoma cruzi , is a serious chronic parasitic disease, currently treated with Nifurtimox (NFX) and Benznidazole…”
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Chimeric Vaccines Designed by Immunoinformatics-Activated Polyfunctional and Memory T Cells That Trigger Protection against Experimental Visceral Leishmaniasis by Brito, Rory Cristiane Fortes De, Ruiz, Jeronimo Conceição, Cardoso, Jamille Mirelle de Oliveira, Ostolin, Thais Lopes Valentim Di Paschoale, Reis, Levi Eduardo Soares, Mathias, Fernando Augusto Siqueira, Aguiar-Soares, Rodrigo Dian de Oliveira, Roatt, Bruno Mendes, Corrêa-Oliveira, Rodrigo, Resende, Daniela de Melo, Reis, Alexandre Barbosa

“…Many vaccine candidates against visceral leishmaniasis (VL) have been proposed; however, to date, none of them have been efficacious for the human or canine…”
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Synthetic Peptides Elicit Strong Cellular Immunity in Visceral Leishmaniasis Natural Reservoir and Contribute to Long-Lasting Polyfunctional T-Cells in BALB/c Mice by De Brito, Rory Cristiane Fortes, Cardoso, Jamille Mirelle de Oliveira, Reis, Levi Eduardo Soares, Mathias, Fernando Augusto Siqueira, Aguiar-Soares, Rodrigo Dian de Oliveira, Teixeira-Carvalho, Andréa, Roatt, Bruno Mendes, Corrêa-Oliveira, Rodrigo, Ruiz, Jeronimo Conceição, Resende, Daniela de Melo, Reis, Alexandre Barbosa

“…Reverse vaccinology or immunoinformatics is a computational methodology which integrates data from in silico epitope prediction, associated to other important…”
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Discovery of Arylpiperazines with Broad-Spectrum Antimicrobial Activity and Favorable Pharmacokinetic Profiles by Oliveira, Douglas Davison da Silva, Silva, Nagela Bernadelli Sousa, Lapierre, Thibault Joseph William Jacques Dit, de Souza, Sara Lemes, Brito, Nícolas Peterson Ferreira, Martinho, Ana Clara Cassiano, Clemente Dias, Renieidy Flávia, Farago, Danilo Nascimento, Michelan-Duarte, Simone, Chelucci, Rafael Consolin, Cruz, Mariza Gabriela Faleiro de Moura Lodi, de Melo Resende, Daniela, Andricopulo, Adriano D, Murta, Silvane Maria Fonseca, Ferreira, Leonardo L G, Gomes Martins, Carlos Henrique, de Oliveira Rezende Júnior, Celso

“…Microorganisms can induce diseases with significant clinical implications for human health. Multidrug-resistant microorganisms have been on the rise worldwide…”
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Hit-to-lead optimization of a pyrazinylpiperazine series against Leishmania infantum and Leishmania braziliensis by Jacques Dit Lapierre, Thibault Joseph William, Cruz, Mariza Gabriela Faleiro de Moura Lodi, Brito, Nícolas Peterson Ferreira, Resende, Daniela de Melo, Souza, Felipe de Oliveira, Pilau, Eduardo Jorge, da Silva, Meryck Felipe Brito, Neves, Bruno Junior, Murta, Silvane Maria Fonseca, Rezende Júnior, Celso de Oliveira

“…An early hit-to-lead optimization of a novel pyrazinylpiperazine series against L. infantum and L. braziliensis has been performed after an extensive SAR…”
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Disruption of multiple copies of the Prostaglandin F2alpha synthase gene affects oxidative stress response and infectivity in Trypanosoma cruzi by Ana Maria Murta Santi, Juliana Martins Ribeiro, João Luís Reis-Cunha, Gabriela de Assis Burle-Caldas, Isabella Fernandes Martins Santos, Paula Alves Silva, Daniela de Melo Resende, Daniella Castanheira Bartholomeu, Santuza Maria Ribeiro Teixeira, Silvane Maria Fonseca Murta

“…Chagas disease, caused by the protozoan Trypanosoma cruzi, is a serious chronic parasitic disease, currently treated with Nifurtimox (NFX) and Benznidazole…”
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Complete Genome Sequence of Type Strain Campylobacter fetus subsp. venerealis NCTC 10354^sup T by Stynen, Ana Paula Reinato, Lage, Andrey Pereira, Moore, Robert J, Rezende, Antonio Mauro, de Resende, Vivian D'Afonseca da Silva, Ruy, Patricia de Cássia, Daher, Nesley, Resende, Daniela de Melo, de Almeida, Sintia Silva, Soares, Siomar de Castro, de Abreu, Vinicius Augusto Carvalho, Rocha, Aryane Aparecida C Magalhães, dos Santos, Anderson Rodrigues, Barbosa, Eudes Guilherme Vieira, Costa, Danielle Fonseca, Dorella, Fernanda Alves, Miyoshi, Anderson, de Lima, Alex Ranieri Jerônimo, Campos, Frederico Davi da Silva, de Sá, Pablo Gomes, Lopes, Thiago Souza, Rodrigues, Ryan Mauricio Araujo, Carneiro, Adriana Ribeiro, Leão, Thiago, Cerdeira, Louise Teixeira, Ramos, Rommel Thiago Jucá, Silva, Artur, Azevedo, Vasco, Ruiz, Jerônimo C

“…Campylobacter fetus subsp. venerealis is the etiologic agent of bovine genital campylobacteriosis, a sexually transmitted disease of cattle that is of…”
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Complete Genome Sequence of Type Strain Campylobacter fetus subsp. venerealis NCTC 10354T by Stynen, Ana Paula Reinato, Lage, Andrey Pereira, Moore, Robert J, Rezende, Antonio Mauro, de Resende, Vivian D'Afonseca da Silva, Ruy, Patricia de Cássia, Daher, Nesley, Resende, Daniela de Melo, de Almeida, Sintia Silva, Soares, Siomar de Castro, de Abreu, Vinicius Augusto Carvalho, Rocha, Aryane Aparecida C. Magalhães, dos Santos, Anderson Rodrigues, Barbosa, Eudes Guilherme Vieira, Costa, Danielle Fonseca, Dorella, Fernanda Alves, Miyoshi, Anderson, de Lima, Alex Ranieri Jerônimo, Campos, Frederico Davi da Silva, de Sá, Pablo Gomes, Lopes, Thiago Souza, Rodrigues, Ryan Mauricio Araujo, Carneiro, Adriana Ribeiro, Leão, Thiago, Cerdeira, Louise Teixeira, Ramos, Rommel Thiago Jucá, Silva, Artur, Azevedo, Vasco, Ruiz, Jerônimo C

“…Campylobacter fetus subsp. venerealis is the etiologic agent of bovine genital campylobacteriosis, a sexually transmitted disease of cattle that is of…”
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