Search Results - "Melo, Sebastião J DE"
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Histological evaluation of the liver of mice with sarcoma-180 treated with salazinic acid
Published in Anais da Academia Brasileira de Ciências (01-01-2023)“…Many of the drugs used to fight cancer cells induce various damage causing hepatotoxic effects which are characterized by tissue changes. The aim of the study…”
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2
Comparative computational studies of 3,4-dihydro-2,6-diaryl-4-oxo-pyrimidine-5-carbonitrile derivatives as potential antinociceptive agents
Published in Molecules (Basel, Switzerland) (16-01-2012)“…In this study, the antinociceptive properties of 3,4-dihydro-2,6-diaryl-4-oxo-pyrimidine-5-carbonitrile derivatives 5a-i at doses of 25 and 50 mg/kg were…”
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3
Synthesis and cytotoxic profile of glycosyl–triazole linked to 1,2,4-oxadiazole moiety at C-5 through a straight-chain carbon and oxygen atoms
Published in European journal of medicinal chemistry (01-09-2009)“…The convergent synthesis of an unusual (but simple) class of compounds 5a– g has been achieved by the copper-catalyzed [3 + 2] cycloaddition reaction of…”
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4
Use of GC/MS to identify chemical constituents and cytotoxic activity of the leaves of Phoradendron mucronatum and Phoradendron microphyllum (Viscaceae)
Published in Anais da Academia Brasileira de Ciências (01-06-2017)“…Phoradendron mucronatum and P. microphyllum are plants that found in tropical and subtropical areas, used in traditional medicine and popularly known as…”
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5
Synthesis and antiinflammatory activity of 4-amino-2-aryl-5-cyano-6-{3- and 4-(N-phthalimidophenyl)} pyrimidines
Published in European journal of medicinal chemistry (01-02-2006)“…Six new 4-amino-5-cyano-2,6-diarylpyrimidines 5a-h has been synthesized in a facile manner by reacting the appropriate arylamidines 4a-d with bisnitriles 3a-e…”
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6
Synthesis of Some Unusual (1,2,4-Oxadiazole)-Linked Hexenopyranosides and Mannopyranosides
Published in Journal of carbohydrate chemistry (01-05-2008)“…A copper-catalyzed reaction of propargyl 4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside with 3-(4-azidophenyl)-1,2,4-oxadiazoles gave the…”
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7
Synthesis, mechanism of formation, and molecular orbital calculations of arylamidoximes
Published in Monatshefte für Chemie (01-11-2009)“…A simple and easy synthesis of ten arylamidoximes from arylnitriles and hydroxylamine is described. The formation of the arylamides has been observed to a much…”
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Synthesis of Some 3-Aryl-1,2,4-oxadiazoles Carrying a Protected L-Alanine Side Chain
Published in Journal of the Brazilian Chemical Society (01-09-1998)“…The synthesis of some 1,2,4-oxadiazole derivatives (4a-d) starting from arylamidoximes 1a-d and N-t-butoxycarbonyl-O-benzyl-L-aspartic acid is described. The…”
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9
Synthesis of new 1,2,4-oxadiazoles carrying (1'S,2'S)-t-butyloxycarbonyl-1-amino-2- methyl-1-butyl and (1'S)-t-butyloxycarbonyl-1'-amino-1'-ethyl groups at C-5
Published in Journal of the Brazilian Chemical Society (01-08-2004)“…A facile and efficient synthesis of 3-aryl-5-[(1S)-t-butyloxycarbonyl-1-amino-(2 S)-methyl-1-butyl)]-1,2,4-oxadiazoles 4a-f and…”
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10
Synthesis of glycosyl-triazole linked 1,2,4-oxadiazoles
Published in Carbohydrate research (26-11-2007)“…The synthesis of four different types of oxadiazoles containing a terminal acetylenic group is described. Reaction of these oxadiazoles with various…”
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Synthesis and antiinflammatory activity of 4-amino-2-aryl-5-cyano-6-{3- and 4-( N-phthalimidophenyl)} pyrimidines 1 1 Taken in part from the Ph.D. thesis (2003) of Emerson Peter da S. Falcão
Published in European journal of medicinal chemistry (2006)“…Six new 4-amino-5-cyano-2,6-diarylpyrimidines 5a– h has been synthesized in a facile manner by reacting the appropriate arylamidines 4a– d with bisnitriles 3a–…”
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