Search Results - "Melo, Robson"

Longipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles by Sayegh, Raphael Santa Rosa, Batista, Isabel de Fátima Correia, Melo, Robson Lopes de, Riske, Karin A, Daffre, Sirlei, Montich, Guillermo, da Silva Junior, Pedro Ismael

“…In contrast to vertebrate immune systems, invertebrates lack an adaptive response and rely solely on innate immunity in which antimicrobial peptides (AMPs)…”
Get full text

Alphastatin-C a new inhibitor of endothelial cell activation is a pro-arteriogenic agent in vivo and retards B16-F10 melanoma growth in a preclinical model by Ferreira, Adilson Kleber, Cristofaro, Brunella, Menezes, Milene Cristina, de Oliveira, Ana Karina, Tashima, Alexandre Keiji, de Melo, Robson Lopes, Silva, Cristiane Castilho Fernandes, Rodriguez, Miryam Guillermina Palomino, Carvalho, Daniela Cajado de Oliveira Souza, de Azevedo, Ricardo Alexandre, Junior, Paulo Luiz de Sá, Mambelli, Lisley Inata, Portaro, Fernanda Vieira, Pardanaud, Luc, Eichmann, Anne, Sant'Anna, Osvaldo Augusto, Faria, Mxarcella

“…Most characterized angiogenic modulators are proteolytic fragments of structural plasma and/or matrix components. Herein, we have identified a novel…”
Get full text

Peptidomics of Three Bothrops Snake Venoms: Insights Into the Molecular Diversification of Proteomes and Peptidomes by Tashima, Alexandre K., Zelanis, André, Kitano, Eduardo S., Ianzer, Danielle, Melo, Robson L., Rioli, Vanessa, Sant'anna, Sávio S., Schenberg, Ana C.G., Camargo, Antônio C.M., Serrano, Solange M.T.

“…Snake venom proteomes/peptidomes are highly complex and maintenance of their integrity within the gland lumen is crucial for the expression of toxin…”
Get full text

Soil carbon stocks and labile fractions of organic matter under agroforestry system in breast of pernambucan altitude by Crespo, Cristiane Maria Gonçalves, Piscoya, Victor Casimiro, Araujo Filho, Renisson Neponuceno de, Lima, Samila Bezerra, Moraes, Alex Souza, França, Manoel Vieira de, Fernandes, Milton Marques, Cunha Filho, Moacyr, Gomes Filho, Raimundo Rodrigues, Cavalcante, Nayane Laisa de Lima, Melo, Robson Carlos Pereira de, Piscoya, Thaisa Folha, Roncal, Jorge Piscoya, Pereira, Ludmilla Morais, Holanda, Francisco Sandro Rodrigues, Pedrotti, Alceu, Feitosa, Thaiana Brunes, Oliveira, Patrick Peres

“…Intense soil preparation and disturbance in crops, over time, reduces the quantity and quality of soil organic matter. Given this context, this work aimed to…”
Get full text

Humic fractions of soil carbon under agroforestry system in altitude swamp Pernambucano by Crespo, Cristiane Maria Gonçalves, Piscoya, Victor Casimiro, Moraes, Alex Souza, França, Manoel Vieira de, Fernandes, Milton Marques, Cunha Filho, Moacyr, Cavalcante, Nayane Laisa de Lima, Melo, Robson Carlos Pereira de, Piscoya, Thaisa Folha, Piscoya-Roncal, Jorge, Pereira, Ludmilla Morais, Gomes Filho, Raimundo Rodrigues, Holanda, Francisco Sandro Rodrigues, Pedrotti, Alceu, Castro, Jamilie Brito de, Araújo Filho, Renisson Neponuceno de

“…MOS (soil organic matter) is a natural carbon reservoir, and divided into different stages of decomposition according to its solubility and structural…”
Get full text

WEPP MODEL FOR RILL EROSION ESTIMATION IN A BRAZILIAN SEMIARID WATERSHED by PISCOYA, VICTOR CASIMIRO, SOUZA, WALDEMIR PEREIRA DE, CANTALICE, JOSÉ RAMON BARROS, CUNHA FILHO, MOACYR, MELO, ROBSON CARLOS PEREIRA DE, ARAÚJO FILHO, RENISSON NEPONUCENO DE

“…ABSTRACT Soil erosion is a major environmental problem in many parts of the world and represents a serious problem for sustainable agriculture and the…”
Get full text

A Lys49 Phospholipase A2, Isolated from Bothrops asper Snake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region by Teixeira, Catarina, Gutiérrez, José Maria, Lomonte, Bruno, Nascimento, Neide Galvão do, Moreira, Vanessa, Leiguez, Elbio, Cristina Giannotti, Karina, Melo, Robson Lopes

“…MT-II, a Lys49PLA2 homologue devoid of catalytic activity from B. asper venom, stimulates inflammatory events in macrophages. We investigated the ability of…”
Get full text

Argininosuccinate Synthetase Is a Functional Target for a Snake Venom Anti-hypertensive Peptide: ROLE IN ARGININE AND NITRIC OXIDE PRODUCTION by Guerreiro, Juliano R, Lameu, Claudiana, Oliveira, Eduardo F, Klitzke, Clécio F, Melo, Robson L, Linares, Edlaine, Augusto, Ohara, Fox, Jay W, Lebrun, Ivo, Serrano, Solange M.T, Camargo, Antonio C.M

“…Bj-BPP-10c is a bioactive proline-rich decapeptide, part of the C-type natriuretic peptide precursor, expressed in the brain and in the venom gland of Bothrops…”
Get full text

Proline rich-oligopeptides: Diverse mechanisms for antihypertensive action by Morais, Katia L.P., Ianzer, Danielle, Miranda, José Rodolfo R., Melo, Robson L., Guerreiro, Juliano R., Santos, Robson A.S., Ulrich, Henning, Lameu, Claudiana

“…•Antihypertensive activity of Bj-proline-rich oligopeptides.•Diversity of mechanisms for antihypertensive action of Bj-proline-rich…”
Get full text

Brain nitric oxide production by a proline-rich decapeptide from Bothrops jararaca venom improves baroreflex sensitivity of spontaneously hypertensive rats by Lameu, Claudiana, Pontieri, Vera, Guerreiro, Juliano R, Oliveira, Eduardo F, da Silva, Carlos Alberto, Giglio, Joyce M, Melo, Robson L, Campos, Ruy R, de Camargo, Antonio Carlos Martins, Ulrich, Henning

“…Baroreflex sensitivity is disturbed in many people with cardiovascular diseases such as hypertension. Brain deficiency of nitric oxide (NO), which is…”
Get full text

A Mycobacterium leprae Hsp65 mutant as a candidate for mitigating lupus aggravation in mice by Marengo, Eliana B, de Moraes, Luciana V, Melo, Robson L, Balan, Andrea, Fernandes, Beatriz L, Tambourgi, Denise V, Rizzo, Luiz Vicente, Sant'Anna, Osvaldo Augusto

“…Hsp60 is an abundant and highly conserved family of intracellular molecules. Increased levels of this family of proteins have been observed in the…”
Get full text

Insights into scorpion venom peptides: Alternative processing of β-KTx propeptide from Tityus serrulatus venom results in a new naturally occurring thimet oligopeptidase inhibitor by Carvalho, Daniela Cajado, Duzzi, Bruno, Kuniyoshi, Alexandre Kazuo, Fioramonte, Mariana, Gozzo, Fábio Cesar, Melo, Robson L., Tambourgi, Denise Vilarinho, Rioli, Vanessa, Portaro, Fernanda Calheta

“…► New pentapeptide KEILG from Tityus serrulatus venom is a EP24.15 inhibitor. ► A selective tool to differentiate EP 24.15 from EP24.16. ► Substitution of one…”
Get full text

Disintegrin-like/cysteine-rich domains of the reprolysin HF3: Site-directed mutagenesis reveals essential role of specific residues by Menezes, Milene C., de Oliveira, Ana Karina, Melo, Robson L., Lopes-Ferreira, Mônica, Rioli, Vanessa, Balan, Andrea, Paes Leme, Adriana F., Serrano, Solange M.T.

“…Little is known about the biochemical properties of the non-catalytic domains of snake venom metalloproteinases (SVMPs). The ECD sequence of the…”
Get full text

Mass spectrometric analysis of the individual variability of Bothrops jararaca venom peptide fraction. Evidence for sex-based variation among the bradykinin-potentiating peptides by Pimenta, Daniel C., Prezoto, Benedito C., Konno, Katsuhiro, Melo, Robson L., Furtado, Maria F., Camargo, Antonio C. M., Serrano, Solange M. T.

“…Variation in the snake venom proteome is well documented and it is a ubiquitous phenomenon at all taxonomical levels. However, variation in the snake venom…”
Get full text

Bradykinin-related peptides in the venom of the solitary wasp Cyphononyx fulvognathus by Picolo, Gisele, Hisada, Miki, Moura, Analuê B., Machado, Maurício F.M., Sciani, Juliana M., Conceição, Isaltino M., Melo, Robson L., Oliveira, Vitor, Lima-Landman, Maria Teresa R., Cury, Yara, Konno, Katsuhiro, Hayashi, Mirian A.F.

“…Biochemical and pharmacological characterization of novel bradykinin-related peptides (BRP) named Cd-146, Thr6-BK, fulvonin and cyphokinin isolated from the…”
Get full text

Carbon and Nitrogen Stocks and Microbiological Activity Under Forest-Pasture System and Traditional Pasture in Pernambuco by Pessôa, Gabriel Carlos Moura, Piscoya, Victor Casimiro, Rolim Neto, Fernando Cartaxo, Araújo Filho, Renisson Neponuceno de, Melo, Robson Carlos Pereira de, Pessôa, Uriel Calisto Moura, Silva, Lucas José de Souza, Cunha Filho, Moacyr, Almeida, Rafael Costa Schaidhauer de, Piscoya, Thaisa Oliveira Folha, Moraes, Alex Souza, Gomes Filho, Raimundo Rodrigues, Medeiros, Raimundo Mainar de, Saboya, Luciano Marcelo Fallé, Pedrotti, Alceu, Holanda, Francisco Sandro Rodrigues, Fernandes, Milton Marques, Santos, Luiz Diego Vidal

“…Abstract An adequate amount of soil organic matter is considered essential for long-term sustainable agriculture, ensuring good productivity. Therefore, the…”
Get full text

Synergic effects between ocellatin-F1 and bufotenine on the inhibition of BHK-21 cellular infection by the rabies virus by Cunha Neto, Rene Dos Santos, Vigerelli, Hugo, Jared, Carlos, Antoniazzi, Marta Maria, Chaves, Luciana Botelho, da Silva, Andréa de Cássia Rodrigues, Melo, Robson Lopes de, Sciani, Juliana Mozer, Pimenta, Daniel C

“…Rabies is an incurable neglected zoonosis with worldwide distribution characterized as a lethal progressive acute encephalitis caused by a lyssavirus. Animal…”
Get full text

The snake venom peptide Bj‐PRO‐7a is a M1 muscarinic acetylcholine receptor agonist by Negraes, Priscilla D., Lameu, Claudiana, Hayashi, Mirian A. F., Melo, Robson L., Camargo, Antônio C. M., Ulrich, Henning

“…Proline‐rich peptides from Bothrops jararaca venom (Bj‐PRO) were characterized based on the capability to inhibit the somatic angiotensin‐converting enzyme…”
Get full text

Activation of leukocyte rolling by the cysteine-rich domain and the hyper-variable region of HF3, a snake venom hemorrhagic metalloproteinase by Menezes, Milene C., Paes Leme, Adriana F., Melo, Robson L., Silva, Carlos A., Della Casa, Maisa, Bruni, Fernanda M., Lima, Carla, Lopes-Ferreira, Mônica, Camargo, Antonio C.M., Fox, Jay W., Serrano, Solange M.T.

“…The functionality of the disintegrin-like/cysteine-rich domains of snake venom metalloproteinases (SVMPs) has been shown to reside in the cysteine-rich region,…”
Get full text

Echinometrin: A novel mast cell degranulating peptide from the coelomic liquid of Echinometra lucunter sea urchin by Sciani, Juliana Mozer, Sampaio, Marlos Cortez, Zychar, Bianca Cestari, de Camargo Gonçalves, Luis Roberto, Giorgi, Renata, de Oliveira Nogueira, Thiago, de Melo, Robson Lopes, de Fátima Pereira Teixeira, Catarina, Pimenta, Daniel Carvalho

“…•Novel peptide isolated from Echinometra lucunter sea urchin.•The peptide acts on mast cells, causing inflammatory effects.•Synthetic analog retains the…”
Get full text