Search Results - "Melo, Luma"

Women in toxicology in the United States by Luma, Melo

“…Since the toxicology field was established, women have played a critical role in it. This article is written to celebrate the 20-year anniversary of the…”
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Loss of hepatic DRP1 exacerbates alcoholic hepatitis by inducing megamitochondria and mitochondrial maladaptation by Ma, Xiaowen, Chen, Allen, Melo, Luma, Clemente-Sanchez, Ana, Chao, Xiaojuan, Ahmadi, Ali Reza, Peiffer, Brandon, Sun, Zhaoli, Sesaki, Hiromi, Li, Tiangang, Wang, Xiaokun, Liu, Wanqing, Bataller, Ramon, Ni, Hong-Min, Ding, Wen-Xing

“…Increased megamitochondria formation and impaired mitophagy in hepatocytes have been linked to the pathogenesis of alcohol-associated liver disease (ALD). This…”
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Endurance training slows breast tumor growth in mice by suppressing Treg cells recruitment to tumors by Hagar, Amit, Wang, Zemin, Koyama, Sachiko, Serrano, Josua Aponte, Melo, Luma, Vargas, Stephanie, Carpenter, Richard, Foley, John

“…Aerobic exercise has been shown to slow tumor progression in rodents and humans, but the mechanisms behind this effect are still unclear. Here we show that…”
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Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure by Ma, Jing, Guillot, Adrien, Yang, Zhihong, Mackowiak, Bryan, Hwang, Seonghwan, Park, Ogyi, Peiffer, Brandon J, Ahmadi, Ali Reza, Melo, Luma, Kusumanchi, Praveen, Huda, Nazmul, Saxena, Romil, He, Yong, Guan, Yukun, Feng, Dechun, Sancho-Bru, Pau, Zang, Mengwei, Cameron, Andrew MacGregor, Bataller, Ramon, Tacke, Frank, Sun, Zhaoli, Liangpunsakul, Suthat, Gao, Bin

“…Intrahepatic neutrophil infiltration has been implicated in severe alcoholic hepatitis (SAH) pathogenesis; however, the mechanism underlying neutrophil-induced…”
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Biotransformation of 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine (TTBP-TAZ) can contribute to high levels of 2,4,6-tribromophenol (2,4,6-TBP) in humans by Zheng, Guomao, Melo, Luma, Chakraborty, Rishika, Klaunig, James E., Salamova, Amina

“…[Display omitted] •2,4,6-TBP was a major hepatic metabolite of TTBP-TAZ in an in vitro experiment.•The transformation rates of TTBP-TAZ to 2,4,6-TBP were 1.3%…”
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Subclinical versus advanced forms of alcohol-related liver disease: Need for early detection by Gómez-Medina, Concepción, Melo, Luma, Martí-Aguado, David, Bataller, Ramón

“…Alcohol-related liver disease (ALD) consists of a wide spectrum of clinical manifestations and pathological features, ranging from asymptomatic patients to…”
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The effect of endurance training on non‐alcoholic fatty liver disease in mice by Melo, Luma, Bilici, Merve, Hagar, Amit, Klaunig, James E.

“…Chronic endurance exercise is a therapeutic strategy in the treatment of non‐alcoholic fatty liver disease (NAFLD). Metabolic, cardiorespiratory, and endocrine…”
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Ceramide synthase 6 (CerS6) is upregulated in alcohol-associated liver disease and exhibits sex-based differences in the regulation of energy homeostasis and lipid droplet accumulation by Jeon, Sookyoung, Scorletti, Eleonora, Dempsey, Joseph, Buyco, Delfin, Lin, Chelsea, Saiman, Yedidya, Bayen, Susovon, Harkin, Julia, Martin, Jasmin, Hooks, Royce, Ogretmen, Besim, Argemi, Josepmaria, Melo, Luma, Bataller, Ramon, Carr, Rotonya M.

“…Alcohol-associated liver disease (ALD) is the leading cause of liver-related mortality worldwide. Current strategies to manage ALD focus largely on advanced…”
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Erratum to: Women in toxicology in the United States by Melo, Luma

“…[This corrects the article DOI: 10.1093/toxres/tfab075.]…”
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How to train a mouse-methodological issues in pre-clinical exercise oncology by Melo, Luma, Hagar, Amit

“…We point at several challenges that current exercise oncology rodent models face, which call their human-relevance into question: the vast majority of…”
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A new aerobic fitness score based on lactate sensing during submaximal exercise by Hagar, Amit, Melo, Luma, Hills, Grace, Kenshur, Nathan, Dickinson, Stephanie

“…Given the known clinical utility of cardiorespiratory fitness, measurement of physiological responses to submaximal exercise may be a feasible approach well…”
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Mechanisms of hepatic cancer by persistent organic pollutants by Klaunig, James E., Melo, Luma, Tilmant, Karen

“…Persistent organic pollutants (POPs) are a group of organic chemicals, as defined by the Stockholm Convention that are persistent in the environment and…”
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On the Interaction of Alkyl-Functionalized Ionic Liquids with Model Proteins: A Spectroscopic and Structural Study by Raw, Juliana, Melo, Luma O., Barbosa, Leandro R.S.

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AKR1B10 as a novel molecular driver of alcohol-associated hepatitis by Hernandez-Tejero, Maria, Clemente, Ana, Melo, Luma, Ravi, Samhita, Argemi, Josep Maria, Atkinson, Stephen, Arab, Juan Pablo, Cabrera, Daniel, Rivera, Paula, Diaz, Luis Antonio, Idalsoaga, Francisco, Cao, Sheng, Shah, Vijay, Behari, Jaideep, Arteel, Gavin, Bataller, Ramon

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TOP-073 - AKR1B10 as a novel molecular driver of alcohol-associated hepatitis by Hernandez-Tejero, Maria, Clemente, Ana, Melo, Luma, Ravi, Samhita, Argemi, Josep Maria, Atkinson, Stephen, Arab, Juan Pablo, Cabrera, Daniel, Rivera, Paula, Diaz, Luis Antonio, Idalsoaga, Francisco, Cao, Sheng, Shah, Vijay, Behari, Jaideep, Arteel, Gavin, Bataller, Ramon

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Letter (brief communication): A pilot study of hemp hull bio gut fibre (BGF) to reduce intestinal permeability in IBS‐BAD by Lupianez‐Merly, Camille, Jencks, Kara, Dilmaghani, Saam, Ferber, Monique, Melo, Luma, Klinken, B. Jan‐Willem, Kalgaonkar, Swati, Camilleri, Michael

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Modulation of Non-alcoholic Fatty Liver Disease by Exercise by Melo de Oliveira, Luma

“…Non-alcoholic fatty liver disease (NAFLD) affects up to one-third of the population in the western countries. Diet is the major cause related to NAFLD, however…”
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