Search Results - "Melo, JB"

Early detection and personalized treatment in oral cancer: the impact of omics approaches by Ribeiro, Ilda Patrícia, Barroso, Leonor, Marques, Francisco, Melo, Joana Barbosa, Carreira, Isabel Marques

“…Oral cancer is one of the most common malignant lesions of the head and neck. This cancer is an aggressive and lethal disease with no significant improvements…”
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Involvement of oxidative stress in the enhancement of acetylcholinesterase activity induced by amyloid beta-peptide by Melo, Joana Barbosa, Agostinho, Paula, Oliveira, Catarina Resende

“…Acetylcholinesterase (AChE) activity is increased within and around amyloid plaques, which are present in Alzheimer's disease (AD) patient's brain. In this…”
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Somatic homozygous loss of SH2B3, and a non-Robertsonian translocation t(15;21)(q25.3;q22.1) with NTRK3 rearrangement, in an adolescent with progenitor B-cell acute lymphoblastic leukemia with the iAMP21 by Capela de Matos, RR, Othman, MAK, Ferreira, GM, Monteso, KCA, de Souza, MT, Rouxinol, M, Melo, JB, Carreira, IM, Abdelhay, E, Liehr, T, Ribeiro, RC, Silva, MLM

“…•Pediatric iAMP21-ALL with somatic non-Rob(15;21), NTRK3 rearrangement, and SH2B3 loss.•Sporadic iAMP21 leukemogenesis through chromothripsis and…”
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Mitochondrial Alterations in Fibroblasts of Early Stage Bipolar Disorder Patients by Marques, Ana P., Resende, Rosa, Silva, Diana F., Batista, Mariana, Pereira, Daniela, Wildenberg, Brigite, Morais, Sofia, Macedo, António, Pais, Cláudia, Melo, Joana B., Madeira, Nuno, Pereira, Cláudia F.

“…This study aims to evaluate whether mitochondrial changes occur in the early stages of bipolar disorder (BD). Using fibroblasts derived from BD patients and…”
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Interstitial 287 kb deletion of 4p16.3 including FGFRL1 gene associated with language impairment and overgrowth by Matoso, Eunice, Ramos, Fabiana, Ferrão, José, Pires, Luís M, Mascarenhas, Alexandra, Melo, Joana B, Carreira, Isabel M

“…We report a male patient with developmental delay carrying an interstitial 4p16.3 deletion of 287 kb, disclosed by oligo array-CGH and inherited from his…”
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Amyloid beta-peptide 25-35 reduces [3H] acetylcholine release in retinal neurons. Involvement of metabolic dysfunction by Melo, Joana Barbosa, Agostinho, Paula, Oliveira, Catarina Resende

“…Cholinergic pathways serve important functions in learning and memory processes. The loss of basal forebrain cholinergic neurons and the presence of senile…”
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Synthesis and Anticancer Evaluation of Thiazacridine Derivatives Reveals New Selective Molecules to Hematopoietic Neoplastic Cells by de Melo Rego, Moacyr J B, de Sena, Wanessa L B, de Moura, Ricardo O, Jacob, Iris T T, Lins E Lins, Thiago U, Pereira, Michelly C, do Carmo A Lima, Maria, Galdino-Pitta, Marina R, da R Pitta, Ivan, da Rocha Pitta, Maira G

“…Cancer has become one of the leading causes of morbidity and mortality worldwide. Limitations associated with existing agents increase the need to develop more…”
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GalNAc-T15 in gastric adenocarcinoma: Characterization according to tissue architecture and cellular location by De Souza Albuquerque, Mário S, Da Silva-Filho, Antônio F, Ferraz Cordeiro, Marina, Deodato de Souza, Maria de Fátima, Quirino, Michael W L, Amorim Lima, Luiza R, Da Rocha Pitta, Maira G, Martins, Mario R, De Melo Rêgo, Moacyr J B

“…Gastric cancer (GC) is the second most common cause of cancer-related deaths in the world. This study aims to investigate the differential tissue expression of…”
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