Search Results - "Melo, Bruno Marcel Silva de"
-
1
P2x7 Receptor Signaling Blockade Reduces Lung Inflammation and Necrosis During Severe Experimental Tuberculosis
Published in Frontiers in cellular and infection microbiology (05-05-2021)“…The risk of developing severe forms of tuberculosis has increased by the acquired immunodeficiency syndrome (AIDS) epidemic, lack of effective drugs to…”
Get full text
Journal Article -
2
S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity
Published in Journal of investigative dermatology (01-09-2023)“…Psoriasis is a chronic inflammatory skin disorder driven by the IL-23/type 3 immune response. However, molecular mechanisms sustaining the chronicity of…”
Get full text
Journal Article -
3
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation
Published in Science immunology (22-10-2021)“…Psoriasis is a chronic inflammatory skin disorder underpinned by dysregulated cytokine signaling. Drugs neutralizing the common p40 subunit of interleukin-12…”
Get more information
Journal Article -
4
IL-23 stabilizes an effector Treg cell program in the tumor microenvironment
Published in Nature immunology (01-03-2024)“…Interleukin-23 (IL-23) is a proinflammatory cytokine mainly produced by myeloid cells that promotes tumor growth in various preclinical cancer models and…”
Get full text
Journal Article -
5
Mycobacterium tuberculosis‐infected alveolar epithelial cells modulate dendritic cell function through the HIF‐1α‐NOS2 axis
Published in Journal of leukocyte biology (01-10-2020)“…Tuberculosis kills more than 1 million people every year, and its control depends on the effective mechanisms of innate immunity, with or without induction of…”
Get full text
Journal Article -
6
IL-23 stabilizes an effector T reg cell program in the tumor microenvironment
Published in Nature immunology (01-03-2024)“…Interleukin-23 (IL-23) is a proinflammatory cytokine mainly produced by myeloid cells that promotes tumor growth in various preclinical cancer models and…”
Get full text
Journal Article -
7
The DNA sensor AIM2 mediates psoriasiform inflammation by inducing type 3 immunity
Published in JCI insight (01-10-2024)“…Psoriasis is a chronic and recurrent inflammatory skin disease characterized by abnormal proliferation and differentiation of keratinocytes and activation of…”
Get full text
Journal Article