Search Results - "Melnikova, Daria N."
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Plant Pathogenesis-Related Proteins PR-10 and PR-14 as Components of Innate Immunity System and Ubiquitous Allergens
Published in Current medicinal chemistry (01-01-2017)“…Pathogenesis-related (PR) proteins are components of innate immunity system in plants. They play an important role in plant defense against pathogens. Lipid…”
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Structural and Immunological Features of PR-10 Allergens: Focusing on the Major Alder Pollen Allergen Aln g 1
Published in International journal of molecular sciences (01-05-2024)“…Today, allergies have become a serious problem. PR-10 proteins are clinically relevant allergens that have the ability to bind hydrophobic ligands, which can…”
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Structural and Immunologic Properties of the Major Soybean Allergen Gly m 4 Causing Anaphylaxis
Published in International journal of molecular sciences (06-12-2022)“…Gly m 4 is the major soybean allergen, causing birch pollen cross allergic reactions. In some cases, Gly m 4-mediated anaphylaxis takes place, but the…”
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Investigation of Sensitization Potential of the Soybean Allergen Gly m 4 by Using Caco-2/Immune Cells Co-Culture Model
Published in Nutrients (01-06-2021)“…The soybean allergen Gly m 4 is known to cause severe allergic reactions including anaphylaxis, unlike other Bet v 1 homologues, which induce mainly local…”
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Features and Possible Applications of Plant Lipid-Binding and Transfer Proteins
Published in Membranes (Basel) (20-12-2022)“…In plants, lipid trafficking within and inside the cell is carried out by lipid-binding and transfer proteins. Ligands for these proteins are building and…”
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How Do Pollen Allergens Sensitize?
Published in Frontiers in molecular biosciences (16-06-2022)“…Plant pollen is one of the main sources of allergens causing allergic diseases such as allergic rhinitis and asthma. Several allergens in plant pollen are…”
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Molecular Insight into Ligand Binding and Transport by the Lentil Lipid Transfer Protein Lc-LTP2: The Role of Basic Amino Acid Residues at Opposite Entrances to the Hydrophobic Cavity
Published in Biomolecules (Basel, Switzerland) (24-11-2023)“…Lipid transfer proteins (LTPs) realize their functions in plants due to their ability to bind and transport various ligands. Structures of many LTPs have been…”
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Impact of Different Lipid Ligands on the Stability and IgE-Binding Capacity of the Lentil Allergen Len c 3
Published in Biomolecules (Basel, Switzerland) (13-12-2020)“…Previously, we isolated the lentil allergen Len c 3, belonging to the class of lipid transfer proteins, cross-reacting with the major peach allergen Pru p 3…”
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Effect of Point Mutations on Structural and Allergenic Properties of the Lentil Allergen Len c 3
Published in Membranes (Basel) (27-11-2021)“…Plant lipid transfer proteins (LTPs) are known to be clinically significant allergens capable of binding various lipid ligands. Recent data showed that lipid…”
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Effects of Salinity and Abscisic Acid on Lipid Transfer Protein Accumulation, Suberin Deposition and Hydraulic Conductance in Pea Roots
Published in Membranes (Basel) (01-10-2021)“…Lipid transfer proteins (LTPs) participate in many important physiological processes in plants, including adaptation to stressors, e.g., salinity. Here we…”
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Do Lipids Influence Gastrointestinal Processing: A Case Study of Major Soybean Allergen Gly m 4
Published in Membranes (Basel) (30-09-2021)“…Previously, we have demonstrated that Gly m 4, one of the major soybean allergens, could pass through the Caco-2 epithelial barrier and have proposed a…”
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A novel lipid transfer protein from the pea Pisum sativum: isolation, recombinant expression, solution structure, antifungal activity, lipid binding, and allergenic properties
Published in BMC plant biology (30-04-2016)“…Plant lipid transfer proteins (LTPs) assemble a family of small (7-9 kDa) ubiquitous cationic proteins with an ability to bind and transport lipids as well as…”
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Ligand Binding Properties of the Lentil Lipid Transfer Protein: Molecular Insight into the Possible Mechanism of Lipid Uptake
Published in Biochemistry (Easton) (28-03-2017)“…The lentil lipid transfer protein, designated as Lc-LTP2, was isolated from Lens culinaris seeds. The protein belongs to the LTP1 subfamily and consists of 93…”
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A novel lipid transfer protein from the dill Anethum graveolens L.: isolation, structure, heterologous expression, and functional characteristics
Published in Journal of peptide science (01-01-2016)“…A novel lipid transfer protein, designated as Ag‐LTP, was isolated from aerial parts of the dill Anethum graveolens L. Structural, antimicrobial, and lipid…”
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Recombinant production and solution structure of lipid transfer protein from lentil Lens culinaris
Published in Biochemical and biophysical research communications (04-10-2013)“…•Lipid transfer protein from lentil seeds (Lc-LTP2) was overexpressed in E. coli.•Antimicrobial activity and spatial structure of the recombinant Lc-LTP2 were…”
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