Search Results - "Melloni, G. E. M."

PML-RARA-associated cooperating mutations belong to a transcriptional network that is deregulated in myeloid leukemias by Ronchini, C, Brozzi, A, Riva, L, Luzi, L, Gruszka, A M, Melloni, G E M, Scanziani, E, Dharmalingam, G, Mutarelli, M, Belcastro, V, Lavorgna, S, Rossi, V, Spinelli, O, Biondi, A, Rambaldi, A, Lo-Coco, F, di Bernardo, D, Pelicci, P G

“…It has been shown that individual acute myeloid leukemia (AML) patients are characterized by one of few initiating DNA mutations and 5–10 cooperating mutations…”
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The E3 ubiquitin ligase WWP1 sustains the growth of acute myeloid leukaemia by Sanarico, A G, Ronchini, C, Croce, A, Memmi, E M, Cammarata, U A, De Antoni, A, Lavorgna, S, Divona, M, Giacò, L, Melloni, G E M, Brendolan, A, Simonetti, G, Martinelli, G, Mancuso, P, Bertolini, F, Coco, F Lo, Melino, G, Pelicci, P G, Bernassola, F

“…The E3 ubiquitin ligase (E3) WWP1 is an oncogenic factor implicated in the maintenance of different types of epithelial cancers. The role of WW…”
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PATRI, a Genomics Data Integration Tool for Biomarker Discovery by Callari, Maurizio, Cesarini, M., Della Vedova, G., Daidone, Maria Grazia, Pettenella, M., Isacchi, A., Bosotti, R., Leone, A., Vescovi, M., Pirchio, M. R., Di Bella, S., Rossi, P., Raddrizzani, L., Melloni, G. E. M., Ukmar, G., Somaschini, A.

“…The availability of genomic datasets in association with clinical, phenotypic, and drug sensitivity information represents an invaluable source for potential…”
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Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups by Riva, L, Ronchini, C, Bodini, M, Lo-Coco, F, Lavorgna, S, Ottone, T, Martinelli, G, Iacobucci, I, Tarella, C, Cignetti, A, Volorio, S, Bernard, L, Russo, A, Melloni, G E M, Luzi, L, Alcalay, M, Dellino, G I, Pelicci, P G

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Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups by Riva, L, Ronchini, C, Bodini, M, Lo-Coco, F, Lavorgna, S, Ottone, T, Martinelli, G, Iacobucci, I, Tarella, C, Cignetti, A, Volorio, S, Bernard, L, Russo, A, Melloni, G E M, Luzi, L, Alcalay, M, Dellino, G I, Pelicci, P G

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Deciphering lipoprotein(a) atherogenicity with use of high-throughput proteomics by Morze, J, Marston, N A, Melloni, G E M, Da Silva, G R, Rynkiewicz, A, Wittenbecher, C

“…Abstract Background Accumulating observational and genetic evidence suggests that lipoprotein(a) [Lp(a)], is significantly more atherogenic than other…”
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Exome sequencing in over 63,000 patients in TIMI trials uncovers pathogenic cardiomyopathy variant carriers with high risk for heart failure and cardiovascular death by Kany, S, Melloni, G E M, Jurgens, S J, Berg, D, Bonaca, M, Giugliano, R P, Wiviott, S D, Bhatt, D L, Steg, P G, Raz, I, Pirruccello, J P, Sabatine, M S, Ruff, C T, Ellinor, P T, Marston, N A

“…Abstract Background Rare genetic variants predisposing to cardiomyopathy (CMP) confer increased risk for adverse events. The prevalence of CMP variants in…”
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Pathogenic cardiomyopathy gene variants inform prognosis in atrial fibrillation: results from exome sequencing in over 17,000 patients in TIMI trials by Jurgens, S, Melloni, G E M, Kany, S, Berg, D D, Bonaca, M P, Giugliano, R P, Wiviott, S D, Bhatt, D L, Steg, P G, Raz, I, Pirruccello, J P, Sabatine, M S, Marston, N A, Ellinor, P T, Ruff, C T

“…Abstract Background Rare genetic variants in cardiomyopathy genes are associated with risk of atrial fibrillation (AF), even in the absence of overt…”
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Erratum: Acute promyelocytic leukemias share cooperative mutations with other myeloid-leukemia subgroups by Riva, L, Ronchini, C, Bodini, M, Lo-Coco, F, Lavorgna, S, Ottone, T, Martinelli, G, Iacobucci, I, Tarella, C, Cignetti, A, Volorio, S, Bernard, L, Russo, A, Melloni, G E M, Luzi, L, Alcalay, M, Dellino, G I, Pelicci, P G

“…Correction to: Blood Cancer Journal (2013) 3, e147; doi: 10.1038/bcj.2013.46; published online 13 September 2013 Since the publication of this article, the…”
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