Search Results - "Mello Junior, Fernando Augusto Rodrigues"
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Targeting aurora kinases as a potential prognostic and therapeutical biomarkers in pediatric acute lymphoblastic leukaemia
Published in Scientific reports (04-12-2020)“…Aurora kinases (AURKA and AURKB) are mitotic kinases with an important role in the regulation of several mitotic events, and in hematological malignancies,…”
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Repeated Cycles of Binge-Like Ethanol Exposure Induces Neurobehavioral Changes During Short- and Long-Term Withdrawal in Adolescent Female Rats
Published in Oxidative medicine and cellular longevity (25-10-2022)“…Alcohol consumption is spread worldwide and can lead to an abuse profile associated with severe health problems. Adolescents are more susceptible to addiction…”
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One binge-type cycle of alcohol plus ketamine exposure induces emotional-like disorders associated with oxidative damage in adolescent female rats
Published in Biomedicine & pharmacotherapy (01-06-2023)“…Drug abuse is a global public health problem among adolescents, with alcohol often used in association with other psychotropic drugs, such as ketamine…”
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Chronic Myelogenous Leukemia with Double Philadelphia Chromosome and Coexpression of p210 and p190 Fusion Transcripts
Published in Genes (25-03-2022)“…The Philadelphia (Ph+) chromosome, t(9;22)(q34;q11.2), originates from a chimeric gene called and is present in more than 90% of CML patients. Most patients…”
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Association between the TPMT3C (rs1142345) Polymorphism and the Risk of Death in the Treatment of Acute Lymphoblastic Leukemia in Children from the Brazilian Amazon Region
Published in Genes (25-09-2020)“…Acute lymphoblastic leukemia (ALL) is the leading cause of death from pediatric cancer worldwide. However, marked ethnic disparities are found in the treatment…”
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Telomerase ( hTERT ) Overexpression Reveals a Promising Prognostic Biomarker and Therapeutical Target in Different Clinical Subtypes of Pediatric Acute Lymphoblastic Leukaemia
Published in Genes (17-10-2021)“…Acute Lymphoblastic Leukemia (ALL) is a neoplasm of the hematopoietic system defined as a clonal expansion of an abnormal lymphoid precursor cell. It mostly…”
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High-density array comparative genomic hybridization detects novel copy number alterations in gastric adenocarcinoma
Published in Anticancer research (01-11-2014)“…To investigate frequent quantitative alterations of intestinal-type gastric adenocarcinoma. We analyzed genome-wide DNA copy numbers of 22 samples and using…”
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Association of genes ARID5B, CEBPE and folate pathway with acute lymphoblastic leukemia in a population from the Brazilian Amazon region
Published in Leukemia research reports (2020)“…Acute Lymphoblastic Leukemia (ALL) is the most common childhood neoplasia. Studies have shown that susceptibility to ALL may be modulated by genetic variables…”
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Research for Cytomegalovirus Mutations Associated With Resistance to Antivirals in Kidney Transplant Receptors
Published in Cell transplantation (01-01-2023)“…Cytomegalovirus (CMV) mutations associated with antiviral resistance have become a major problem related to high mortality in kidney transplant patients. The…”
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PARP1 Characterization as a Potential Biomarker for BCR::ABL1 p190+ Acute Lymphoblastic Leukemia
Published in Cancers (22-11-2023)“…Detection of t(9;22), and consequent fusion, is still a marker of worse prognosis for acute lymphoblastic leukemia (ALL), with resistance to tyrosine-kinase…”
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Role of miRNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer
Published in World journal of gastroenterology : WJG (21-09-2016)“…Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large…”
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Influence of variants of the drosha , mir499a , and mir938 genes on susceptibility to acute lymphoblastic leukemia in an admixed population from the brazilian amazon
Published in American journal of translational research (01-01-2020)“…Acute Lymphoblastic Leukemia (ALL) is the most common type of cancer in children. Polymorphisms that alter the normal function of the microRNAs involved in the…”
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Role of mi RNAs and their potential to be useful as diagnostic and prognostic biomarkers in gastric cancer
Published in 世界胃肠病学杂志:英文版 (2016)“…Alterations in epigenetic control of gene expression play an important role in many diseases, including gastric cancer. Many studies have identified a large…”
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PARP1 Characterization as a Potential Biomarker for IBCR::ABL1/I p190+ Acute Lymphoblastic Leukemia
Published in Cancers (01-11-2023)“…Acute lymphoblastic leukemia (ALL) is the most common childhood cancer and the presence of BCR::ABL1 fusion in p190 isoform is a marker for worse prognosis,…”
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Amplificação dos genes ADAM3A, ADAM6 e DMBT1 em pacientes com Leucemia Linfoblástica Aguda
Published in Semina. Ciências biológicas e da saúde (16-02-2018)“…A leucemia linfoblástica aguda (LLA), assim como outros tipos de câncer, é um processo de múltiplas etapas caracterizado por alterações iniciais e secundárias…”
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Association of PARP1 Expression Levels and Clinical Parameters in Different Leukemic Subtypes With BCR::ABL1 p190+ Translocation
Published in Cancer diagnosis & prognosis (01-09-2024)“…Although the reciprocal translocation t(9;22)(q34;q11) is a hallmark of chronic myeloid leukemia (CML), it is also present in acute lymphoblastic leukemia…”
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