Search Results - "Mello, Bruna Stefânia Ferreira"
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Effects of doxycycline on depressive-like behavior in mice after lipopolysaccharide (LPS) administration
Published in Journal of psychiatric research (01-10-2013)“…Abstract Current evidences support inflammation, oxidative and nitrogen stress, as well as brain-derived neurotrophic factor (BDNF) signaling mechanisms as…”
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Neonatal Immune Challenge with Lipopolysaccharide Triggers Long-lasting Sex- and Age-related Behavioral and Immune/Neurotrophic Alterations in Mice: Relevance to Autism Spectrum Disorders
Published in Molecular neurobiology (01-05-2018)“…Early-life challenges, particularly infections and stress, are related to neuropsychiatric disorders such as autism and schizophrenia. Here, we conducted a…”
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Time course of the effects of lipopolysaccharide on prepulse inhibition and brain nitrite content in mice
Published in European journal of pharmacology (05-08-2013)“…The systemic administration of lipopolysaccharide (LPS) induces time-dependent behavioral alterations, which are related to sickness behavior and depression…”
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Doxycycline at subantimicrobial dose combined with escitalopram reverses depressive-like behavior and neuroinflammatory hippocampal alterations in the lipopolysaccharide model of depression
Published in Journal of affective disorders (01-09-2021)“…•DOXY alone or DOXY+ESC reduced hippocampal Iba-1 expression and IL-1β levels.•DOXY+ESC reversed the increase in NF-kBp65 and TNFα levels induced by LPS.•DOXY…”
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Sex influences in behavior and brain inflammatory and oxidative alterations in mice submitted to lipopolysaccharide-induced inflammatory model of depression
Published in Journal of neuroimmunology (15-07-2018)“…Peripheral inflammation induced by lipopolysaccharide (LPS) causes a behavioral syndrome with translational relevance for depression. This mental disorder is…”
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Two-hit model of schizophrenia induced by neonatal immune activation and peripubertal stress in rats: Study of sex differences and brain oxidative alterations
Published in Behavioural brain research (28-07-2017)“…•We developed a new two-hit model of schizophrenia with neonatal poly(I:C) challenge.•Sex differences were observed in the behavior of rats exposed to our…”
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