Search Results - "Mellgård, B."

Structure and Function of Recombinant versus Plasma-Derived von Willebrand Factor and Impact on Multimer Pharmacokinetics in von Willebrand Disease by Gritsch, Herbert, Schrenk, Gerald, Weinhappl, Nina, Mellgard, Bjorn, Ewenstein, Bruce, Turecek, Peter L

“…Background: Recombinant von Willebrand factor (rVWF, vonicog alfa) is a purified VWF concentrate produced from Chinese hamster ovary cells. rVWF is not exposed…”
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A Rat Model of Chronic Helicobacter pylori Infection: Studies of Epithelial Cell Turnover and Gastric Ulcer Healing by LI, H, KALIES, I, MELLGARD, B, HELANDER, H. F

“…Background: Our aim was to infect rats with Helicobacter pylori and to study the effects of the infection on the gastric mucosa in normal and in ulcer-operated…”
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Prucalopride induces high‐amplitude propagating contractions in the colon of patients with chronic constipation: a randomized study by Miner, P. B., Camilleri, M., Burton, D., Achenbach, H., Wan, H., Dragone, J., Mellgard, B.

“…Background This study compared prucalopride, a selective, prokinetic, 5‐HT4 receptor agonist, with polyethylene glycol 3350 + electrolytes (PEG3350), an…”
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Inoculation of VacA− and CagA− Helicobacter pylori Delays Gastric Ulcer Healing in the Rat by Li, H., Mellgård, B., Helander, H. F.

“…Background: Helicobacter pylori is associated with peptic ulcer disease. In the present study, the influence of VacA and CagA− H. pylori on gastric ulcer…”
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OC 14.2 Pharmacokinetic Characteristics of ADAMTS13 in Patients with Congenital Thrombotic Thrombocytopenic Purpura: Interim Results from a Phase 3 Randomized, Controlled, Open-Label, Crossover Study by Cataland, S., Patel, M., Mellgård, B., Ortel, T., Scully, M., Wang, L., Windyga, J., Bhattacharya, I.

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OC 14.1 Phase 3 Prospective, Randomized, Controlled, Open-Label, Multicenter, Crossover Study of Recombinant ADAMTS13 in Patients with Congenital Thrombotic Thrombocytopenic Purpura by Scully, M., Windyga, J., Mellgård, B., Ortel, T., Li, H., Ayash-Rashkovsky, M., Cataland, S., Wang, L.

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OC 14.4 Recombinant ADAMTS13 Prophylaxis in Patients with Congenital Thrombotic Thrombocytopenic Purpura: Interim Analysis from Phase 3B Continuation Study by Coppo, P., Patwari, P., Mellgård, B., Li, H., Scully, M., Matsumoto, M., Windyga, J., Ortel, T., Cataland, S., Knoebl, P., Yu, Z., Wang, L.

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Local acid production and Helicobacter pylori: a unifying hypothesis of gastroduodenal disease by Lee, A, Dixon, M F, Danon, S J, Kuipers, E, Mégraud, F, Larsson, H, Mellgård, B

“…We aimed to produce a unifying hypothesis to explain the different locations of peptic ulcer and gastritis observed in different populations. The…”
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Structure−Activity Relationship of 2-[[(2-Pyridyl)methyl]thio]-1H- benzimidazoles as Anti Helicobacter pylori Agents in Vitro and Evaluation of their in Vivo Efficacy by Kühler, Thomas C, Swanson, Marianne, Shcherbuchin, Vladimir, Larsson, Håkan, Mellgård, Björn, Sjöström, Jan-Eric

“…A relationship between the structure of 21 2-[[(2-pyridyl)methyl]thio]-1H-benzimidazoles (6) and their anti He l icobacter py l ori activity expressed as…”
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Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial by Hueber, Wolfgang, Sands, Bruce E, Lewitzky, Steve, Vandemeulebroecke, Marc, Reinisch, Walter, Higgins, Peter D R, Wehkamp, Jan, Feagan, Brian G, Yao, Michael D, Karczewski, Marek, Karczewski, Jacek, Pezous, Nicole, Bek, Stephan, Bruin, Gerard, Mellgard, Bjoern, Berger, Claudia, Londei, Marco, Bertolino, Arthur P, Tougas, Gervais, Travis, Simon P L

“…The authors tested whether the anti-interleukin (IL)-17A monoclonal antibody secukinumab was safe and effective for the treatment of active Crohn's disease. In…”
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Helicobacter pylori-antigen-binding fragments expressed on the filamentous M13 phage prevent bacterial growth by Cao, Jun, Sun, Yi-qian, Berglindh, Thomas, Mellgård, Björn, Li, Zhao-qi, Mårdh, Bibbi, Mårdh, Sven

“…Colonization of the human stomach by Helicobacter pylori is associated with the development of gastritis, duodenal ulcer, mucosa-associated lymphoid tissue…”
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Genetic variation in DLG5 is associated with inflammatory bowel disease by Lagerstrom-Fermer, Maria, Hampe, Jochen, Rosenstiel, Philip, Stoll, Monika, Albrecht, Mario, Corneliussen, Brit, Foelsch, Ulrich R, Schreiber, Stefan, Croucher, Peter J P, Waetzig, Georg H, Lengauer, Thomas, Costello, Christine M, Mellgard, Bjorn, Seegert, Dirk, Mathew, Christopher G, Nikolaus, Susanna, Koch, W Andreas, Pierrou, Stefan

“…Crohn disease and ulcerative colitis are two subphenotypes of inflammatory bowel disease (IBD), a complex disorder resulting from gene-environment interaction…”
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A comparison of oligonucleotide and cDNA-based microarray systems by Mah, Nancy, Thelin, Anders, Lu, Tim, Nikolaus, Susanna, Kuhbacher, Tanja, Gurbuz, Yesim, Eickhoff, Holger, Kloppel, Gunther, Lehrach, Hans, Mellgard, Bjorn, Costello, Christine M, Schreiber, Stefan

“…1 First Department of Medicine, Christian-Albrechts-University Kiel, D-24105 Kiel, Germany 2 AstraZeneca R&D Mölndal, S-43183 Mölndal, Sweden 3 Department of…”
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Inoculation of VacA and CagA Helicobacter pylori delays gastric ulcer healing in the rat by Li, Hong, Mellgård, B, Helander, H.F

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Design and Synthesis of Dihydrofolate Reductase Inhibitors Encompassing a Bridging Ester Group. Evaluation in a Mouse Colitis Model by Graffner-Nordberg, Malin, Fyfe, Meredith, Brattsand, Ralph, Mellgård, Björn, Hallberg, Anders

“…Crohn's disease is a chronic inflammatory bowel disease characterized by inflammation of both the small and large intestines. Methotrexate (MTX), a classical…”
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Anti-inflammatory effects of budesonide in intestinal epithelial cells by Fredin, Maria Fritsch, Ulfhammer, Erik, Rhedin, Magdalena, Melgar, Silvia, Mellgård, Björn, Peterson, Anders

“…The glucocorticosteroid budesonide is one of the mainstay treatments in inflammatory bowel disease. The aim of this study was to investigate its effects on…”
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Helicobacter pylori-antigen-binding fragments expressed on the filamentous M13 phage prevent bacterial growth by Cao, J, Sun, Y-Q, Berglindh, T, Mellgard, B, Li, Z-Q, Mardh, B, Mardh, S

“…Colonization of the human stomach by Helicobacter pylori is associated with the development of gastritis, duodenal ulcer, mucosa-associated lymphoid tissue…”
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