Search Results - "Mellert, David J"

Sexual-dimorphism in human immune system aging by Márquez, Eladio J., Chung, Cheng-han, Marches, Radu, Rossi, Robert J., Nehar-Belaid, Djamel, Eroglu, Alper, Mellert, David J., Kuchel, George A., Banchereau, Jacques, Ucar, Duygu

“…Differences in immune function and responses contribute to health- and life-span disparities between sexes. However, the role of sex in immune system aging is…”
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High-throughput deconvolution of 3D organoid dynamics at cellular resolution for cancer pharmacology with Cellos by Mukashyaka, Patience, Kumar, Pooja, Mellert, David J., Nicholas, Shadae, Noorbakhsh, Javad, Brugiolo, Mattia, Courtois, Elise T., Anczukow, Olga, Liu, Edison T., Chuang, Jeffrey H.

“…Three-dimensional (3D) organoid cultures are flexible systems to interrogate cellular growth, morphology, multicellular spatial architecture, and cellular…”
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Midline crossing by gustatory receptor neuron axons is regulated by fruitless, doublesex and the Roundabout receptors by Mellert, David J, Knapp, Jon-Michael, Manoli, Devanand S, Meissner, Geoffrey W, Baker, Bruce S

“…Although nervous system sexual dimorphisms are known in many species, relatively little is understood about the molecular mechanisms generating these…”
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Genetic and Environmental Control of Neurodevelopmental Robustness in Drosophila by Mellert, David J, Williamson, W Ryan, Shirangi, Troy R, Card, Gwyneth M, Truman, James W

“…Interindividual differences in neuronal wiring may contribute to behavioral individuality and affect susceptibility to neurological disorders. To investigate…”
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doublesex functions early and late in gustatory sense organ development by Mellert, David J, Robinett, Carmen C, Baker, Bruce S

“…Somatic sexual dimorphisms outside of the nervous system in Drosophila melanogaster are largely controlled by the male- and female-specific Doublesex…”
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Development of a Cardiac Sarcomere Functional Genomics Platform to Enable Scalable Interrogation of Human TNNT2 Variants by Pettinato, Anthony M., Ladha, Feria A., Mellert, David J., Legere, Nicholas, Cohn, Rachel, Romano, Robert, Thakar, Ketan, Chen, Yu-Sheng, Hinson, J. Travis

“…BACKGROUND:Pathogenic TNNT2 variants are a cause of hypertrophic and dilated cardiomyopathies, which promote heart failure by incompletely understood…”
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Transvection is common throughout the Drosophila genome by Mellert, David J, Truman, James W

“…Higher-order genome organization plays an important role in transcriptional regulation. In Drosophila, somatic pairing of homologous chromosomes can lead to…”
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A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice by Bubier, Jason A, Philip, Vivek M, Quince, Christopher, Campbell, James, Zhou, Yanjiao, Vishnivetskaya, Tatiana, Duvvuru, Suman, Blair, Rachel Hageman, Ndukum, Juliet, Donohue, Kevin D, Foster, Carmen M, Mellert, David J, Weinstock, George, Culiat, Cymbeline T, O’Hara, Bruce F, Palumbo, Anthony V, Podar, Mircea, Chesler, Elissa J

“…Abstract Host genetic diversity provides a variable selection environment and physiological context for microbiota and their interaction with host physiology…”
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Functional dissection of the neural substrates for sexual behaviors in Drosophila melanogaster by Meissner, Geoffrey W, Manoli, Devanand S, Chavez, Jose F, Knapp, Jon-Michael, Lin, Tasha L, Stevens, Robin J, Mellert, David J, Tran, David H, Baker, Bruce S

“…The male-specific Fruitless proteins (FruM) act to establish the potential for male courtship behavior in Drosophila melanogaster and are expressed in small…”
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Abstract A032: Cellos : High-throughput deconvolution of 3D organoid dynamics at cellular resolution for cancer pharmacology by Mukashyaka, Patience, Kumar, Pooja, Mellert, David J., Nicholas, Shadae, Noorbakhsh, Javad, Brugiolo, Mattia, Anczukow, Olga, Liu, Edison T., Chuang, Jeffrey H.

“…Three-dimensional (3D) culture models, such as organoids, are flexible systems to interrogate cellular evolution, cellular growth and morphology, multicellular…”
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A Microbe Associated with Sleep Revealed by a Novel Systems Genetic Analysis of the Microbiome in Collaborative Cross Mice by Bubier, Jason A, Philip, Vivek M, Quince, Christopher, Campbell, James, Zhou, Yanjiao, Vishnivetskaya, Tatiana, Duvvuru, Suman, Blair, Rachel Hageman, Ndukum, Juliet, Donohue, Kevin D, Foster, Carmen M, Mellert, David J, Weinstock, George, Culiat, Cymbeline T, O'Hara, Bruce F, Palumbo, Anthony V, Podar, Mircea, Chesler, Elissa J

“…Host genetic diversity provides a variable selection environment and physiological context for microbiota and their interaction with host physiology. Using a…”
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