Search Results - "Mellem, Jerry E."

Neuronal Activity and CaMKII Regulate Kinesin-Mediated Transport of Synaptic AMPARs by Hoerndli, Frédéric J., Wang, Rui, Mellem, Jerry E., Kallarackal, Angy, Brockie, Penelope J., Thacker, Colin, Madsen, David M., Maricq, Andres V.

“…Excitatory glutamatergic synaptic transmission is critically dependent on maintaining an optimal number of postsynaptic AMPA receptors (AMPARs) at each synapse…”
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Kinesin-1 Regulates Synaptic Strength by Mediating the Delivery, Removal, and Redistribution of AMPA Receptors by Hoerndli, Frédéric J., Maxfield, Dane A., Brockie, Penelope J., Mellem, Jerry E., Jensen, Erica, Wang, Rui, Madsen, David M., Maricq, Andres V.

“…A primary determinant of the strength of neurotransmission is the number of AMPA-type glutamate receptors (AMPARs) at synapses. However, we still lack a…”
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Cornichons Control ER Export of AMPA Receptors to Regulate Synaptic Excitability by Brockie, Penelope J., Jensen, Michael, Mellem, Jerry E., Jensen, Erica, Yamasaki, Tokiwa, Wang, Rui, Maxfield, Dane, Thacker, Colin, Hoerndli, Frédéric, Dunn, Patrick J., Tomita, Susumu, Madsen, David M., Maricq, Andres V.

“…The strength of synaptic communication at central synapses depends on the number of ionotropic glutamate receptors, particularly the class gated by the agonist…”
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Mechanistic and structural studies reveal NRAP-1-dependent coincident activation of NMDARs by Goodell, Dayton J., Whitby, Frank G., Mellem, Jerry E., Lei, Ning, Brockie, Penelope J., Maricq, Aleksander J., Eckert, Debra M., Hill, Christopher P., Madsen, David M., Maricq, Andres V.

“…N-methyl-D-aspartate (NMDA)-type ionotropic glutamate receptors have essential roles in neurotransmission and synaptic plasticity. Previously, we identified an…”
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The SOL-2/Neto Auxiliary Protein Modulates the Function of AMPA-Subtype Ionotropic Glutamate Receptors by Wang, Rui, Mellem, Jerry E., Jensen, Michael, Brockie, Penelope J., Walker, Craig S., Hoerndli, Frédéric J., Hauth, Linda, Madsen, David M., Maricq, Andres V.

“…The neurotransmitter glutamate mediates excitatory synaptic transmission by gating ionotropic glutamate receptors (iGluRs). AMPA receptors (AMPARs), a subtype…”
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Evolutionary Conserved Role for TARPs in the Gating of Glutamate Receptors and Tuning of Synaptic Function by Wang, Rui, Walker, Craig S., Brockie, Penelope J., Francis, Michael M., Mellem, Jerry E., Madsen, David M., Maricq, Andres V.

“…Neurotransmission in the brain is critically dependent on excitatory synaptic signaling mediated by AMPA-class ionotropic glutamate receptors (AMPARs). AMPARs…”
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Decoding of Polymodal Sensory Stimuli by Postsynaptic Glutamate Receptors in C. elegans by Mellem, Jerry E., Brockie, Penelope J., Zheng, Yi, Madsen, David M., Maricq, Andres V.

“…The C. elegans polymodal ASH sensory neurons detect mechanical, osmotic, and chemical stimuli and release glutamate to signal avoidance responses. To…”
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SOL-1 is a CUB-domain protein required for GLR-1 glutamate receptor function in C. elegans by Maricq, Andres V, Zheng, Yi, Mellem, Jerry E, Brockie, Penelope J, Madsen, David M

“…Ionotropic glutamate receptors (iGluRs) mediate most excitatory synaptic signalling between neurons. Binding of the neurotransmitter glutamate causes a…”
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Neuronal Control of Locomotion in C. elegans Is Modified by a Dominant Mutation in the GLR-1 Ionotropic Glutamate Receptor by Zheng, Yi, Brockie, Penelope J, Mellem, Jerry E, Madsen, David M, Maricq, Andres V

“…How simple neuronal circuits control behavior is not well understood at the molecular or genetic level. In Caenorhabditis elegans, foraging behavior consists…”
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Reconstitution of Invertebrate Glutamate Receptor Function Depends on Stargazin-Like Proteins by Walker, Craig S., Brockie, Penelope J., Madsen, David M., Francis, Michael M., Zheng, Yi, Koduri, Sri, Mellem, Jerry E., Strutz-Seebohm, Nathalie, Maricq, Andres V.

“…α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors (AMPARs) are a major subtype of ionotropic glutamate receptors (iGluRs) that mediate…”
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The Rho/Rac-Family Guanine Nucleotide Exchange Factor VAV-1 Regulates Rhythmic Behaviors in C. elegans by Norman, Kenneth R., Fazzio, Robert T., Mellem, Jerry E., Espelt, Maria V., Strange, Kevin, Beckerle, Mary C., Maricq, Andres V.

“…Rhythmic behaviors are a fundamental feature of all organisms. Pharyngeal pumping, the defecation cycle, and gonadal-sheath-cell contractions are three…”
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NRAP-1 Is a Presynaptically Released NMDA Receptor Auxiliary Protein that Modifies Synaptic Strength by Lei, Ning, Mellem, Jerry E., Brockie, Penelope J., Madsen, David M., Maricq, Andres V.

“…NMDA receptors (NMDARs) are a subtype of postsynaptic ionotropic glutamate receptors that function as molecular coincidence detectors, have critical roles in…”
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SOL-1 Is an Auxiliary Subunit That Modulates the Gating of GLR-1 Glutamate Receptors in Caenorhabditis elegans by Zheng, Yi, Brockie, Penelope J., Mellem, Jerry E., Madsen, David M., Walker, Craig S., Francis, Michael M., Maricq, Andres V.

“…Most rapid excitatory synaptic signaling in the brain is mediated by postsynaptic ionotropic glutamate receptors (iGluRs) that are gated open by the…”
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MAPK signaling and a mobile scaffold complex regulate AMPA receptor transport to modulate synaptic strength by Hoerndli, Frédéric J., Brockie, Penelope J., Wang, Rui, Mellem, Jerry E., Kallarackal, Angy, Doser, Rachel L., Pierce, Dayton M., Madsen, David M., Maricq, Andres V.

“…Synaptic plasticity depends on rapid experience-dependent changes in the number of neurotransmitter receptors. Previously, we demonstrated that motor-mediated…”
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Action potentials contribute to neuronal signaling in C. elegans by Maricq, Andres V, Mellem, Jerry E, Brockie, Penelope J, Madsen, David M

“…Small, high-impedance neurons with short processes, similar to those found in the soil nematode Caenorhabditis elegans, are predicted to transmit electrical…”
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Clathrin-Mediated Endocytosis Is Required for Compensatory Regulation of GLR-1 Glutamate Receptors after Activity Blockade by Grunwald, Maria E., Mellem, Jerry E., Strutz, Nathalie, Maricq, Andres V., Kaplan, Joshua M., Goodman, Corey S.

“…Chronic changes in neural activity trigger a variety of compensatory homeostatic mechanisms by which neurons maintain a normal level of synaptic input. Here we…”
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Memory in Caenorhabditis elegans Is Mediated by NMDA-Type Ionotropic Glutamate Receptors by Kano, Takashi, Brockie, Penelope J., Sassa, Toshihiro, Fujimoto, Hiroyuki, Kawahara, Yasushi, Iino, Yuichi, Mellem, Jerry E., Madsen, David M., Hosono, Ryuji, Maricq, Andres V.

“…Learning and memory are essential processes of both vertebrate and invertebrate nervous systems that allow animals to survive and reproduce. The…”
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Reply to "First report of action potentials in a C. elegans neuron is premature" by Mellem, Jerry E, Brockie, Penelope J, Madsen, David M, Maricq, Andres V

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Bridging the gap between genes and behavior: recent advances in the electrophysiological analysis of neural function in Caenorhabditis elegans by Francis, Michael M., Mellem, Jerry E., Maricq, Andres Villu

“…The nematode Caenorhabditis elegans has long been popular with researchers interested in fundamental issues of neural development, sensory processing and…”
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Neuronal Toxicity in Caenorhabditis elegans from an Editing Site Mutant in Glutamate Receptor Channels by Aronoff, Rachel, Mellem, Jerry E, Maricq, Andres Villu, Sprengel, Rolf, Seeburg, Peter H

“…Ionotropic glutamate receptors (iGluRs) in Caenorhabditis elegans are predicted to have high permeability for Ca2+ because of glutamine (Q) residues in the…”
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