Search Results - "Melle, I"
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Published in European psychiatry (01-04-2021)“…There is a considerable overlap of psychotic and mood symptoms in patients with severe mental disorders, and a large proportion of patients meeting diagnostic…”
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Hallucinations without delusions in patients with first-episode psychosis: Clinical correlates and implications for pathophysiological models
Published in European psychiatry (01-03-2016)“…Introduction The symptomatic distribution in schizophrenia spectrum disorder is heterogeneous. Patients may experience hallucinations, delusions and…”
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Identifying early signs of Treatment Resistance in First Episode Psychosis to revise and aid further treatment
Published in European psychiatry (01-03-2023)“…Introduction Approximately 1/3 of patients with first episode psychosis (FEP) will not benefit from antipsychotic medications and are considered treatment…”
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Do prospective longitudinal studies of bipolar disorder support the hypothesis of neuroprogression?
Published in European psychiatry (01-03-2023)“…Introduction Bipolar I disorder is a mental disorder with the risk of severe clinical outcomes. Bipolar disorder was initially defined based on having a better…”
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The relationship between visual hallucinations, functioning and suicidality over the course of illness: a 10-year follow-up study in first-episode psychosis
Published in European psychiatry (01-03-2023)“…Introduction Visual hallucinations are a common symptom across psychotic disorders and have been linked to illness severity, impaired functioning, and…”
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Sleep problems in bipolar disorders: more than just insomnia
Published in Acta psychiatrica Scandinavica (01-05-2016)“…Objective Sleep problems in bipolar disorder (BD) are common, but reported rates vary from 10% to 80%, depending on definitions, methodologies and management…”
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Early detection of psychosis: positive effects on 5-year outcome
Published in Psychological medicine (01-07-2011)“…During the last decades we have seen a new focus on early treatment of psychosis. Several reviews have shown that duration of untreated psychosis (DUP) is…”
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Lifetime and point prevalence of psychotic symptoms in adults with bipolar disorders: a systematic review and meta-analysis
Published in Psychological medicine (01-10-2022)“…Psychotic symptoms, that we defined as delusions or hallucinations, are common in bipolar disorders (BD). This systematic review and meta-analysis aims to…”
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Affective lability mediates the association between childhood trauma and suicide attempts, mixed episodes and co-morbid anxiety disorders in bipolar disorders
Published in Psychological medicine (01-04-2017)“…Many studies have shown associations between a history of childhood trauma and more severe or complex clinical features of bipolar disorders (BD), including…”
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Association between cytokine levels, verbal memory and hippocampus volume in psychotic disorders and healthy controls
Published in Acta psychiatrica Scandinavica (01-01-2016)“…Objective We investigated whether elevated plasma levels of immune markers were associated with verbal memory and hippocampal subfield volumes in patients with…”
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Polygenic risk score and the psychosis continuum model
Published in Acta psychiatrica Scandinavica (01-10-2014)“…Objective Schizophrenia (SZ) and bipolar disorder (BD) are heritable, polygenic disorders with shared clinical characteristics and genetic risk indicating a…”
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Additive effects of childhood abuse and cannabis abuse on clinical expressions of bipolar disorders
Published in Psychological medicine (01-06-2014)“…Previous studies of bipolar disorders indicate that childhood abuse and substance abuse are associated with the disorder. Whether both influence the clinical…”
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Neurocognitive Dysfunction in Bipolar and Schizophrenia Spectrum Disorders Depends on History of Psychosis Rather Than Diagnostic Group
Published in Schizophrenia bulletin (01-01-2011)“…Neurocognitive dysfunction is milder in bipolar disorders than in schizophrenia spectrum disorders, supporting a dimensional approach to severe mental…”
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Childhood trauma is associated with increased brain responses to emotionally negative as compared with positive faces in patients with psychotic disorders
Published in Psychological medicine (01-03-2017)“…Childhood trauma increases risk of a range of mental disorders including psychosis. Whereas the mechanisms are unclear, previous evidence has implicated…”
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Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder
Published in Journal of affective disorders (01-09-2019)“…•Recurrent suicide attempts (RSA) regarded the majority of suicide attempters.•RSA were associated to tobacco smoking independently from other…”
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Cardiovascular risk remains high in schizophrenia with modest improvements in bipolar disorder during past decade
Published in Acta psychiatrica Scandinavica (01-04-2019)“…Objective While CVD risk has decreased in the general population during the last decade, the situation in patients with schizophrenia (SCZ) and bipolar…”
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Premorbid cannabis use is associated with more symptoms and poorer functioning in schizophrenia spectrum disorder
Published in Psychological medicine (01-11-2016)“…Cannabis use disorder is associated with an earlier age at onset and a more severe outcome of schizophrenia spectrum disorders. The role of cannabis use before…”
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Increased MRI-based cortical grey/white-matter contrast in sensory and motor regions in schizophrenia and bipolar disorder
Published in Psychological medicine (01-07-2016)“…Schizophrenia and bipolar disorder share genetic risk factors and one possible illness mechanism is abnormal myelination. T1-weighted magnetic resonance…”
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No progressive brain changes during a 1-year follow-up of patients with first-episode psychosis
Published in Psychological medicine (01-02-2016)“…First-episode psychosis (FEP) patients show structural brain abnormalities. Whether the changes are progressive or not remain under debate, and the results…”
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“Why shouldn’t I expect things from life?” – what people with lived experience from psychosis highlight as important to their personally defined long-term recovery process
Published in European psychiatry (01-03-2023)“…Introduction Many people with lived experience from psychosis recover and thrive, contrary to the common stigmatizing belief that they will be chronic…”
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