Search Results - "Mellado, E."

Population-Based Survey of Filamentous Fungi and Antifungal Resistance in Spain (FILPOP Study) by ALASTRUEY-IZQUIERDO, A, MELLADO, E, PELAEZ, T, PEMAN, J, ZAPICO, S, ALVAREZ, M, RODRIGUEZ-TUDELA, J. L, CUENCA-ESTRELLA, M

“…Erratum ( vol. 57 , p. 4604 ) Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Prospective multicenter international surveillance of azole resistance in Aspergillus fumigatus by van der Linden, J W M, Arendrup, M C, Warris, A, Lagrou, K, Pelloux, H, Hauser, P M, Chryssanthou, E, Mellado, E, Kidd, S E, Tortorano, A M, Dannaoui, E, Gaustad, P, Baddley, J W, Uekötter, A, Lass-Flörl, C, Klimko, N, Moore, C B, Denning, D W, Pasqualotto, A C, Kibbler, C, Arikan-Akdagli, S, Andes, D, Meletiadis, J, Naumiuk, L, Nucci, M, Melchers, W J G, Verweij, P E

“…To investigate azole resistance in clinical Aspergillus isolates, we conducted prospective multicenter international surveillance. A total of 3,788 Aspergillus…”
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A New Aspergillus fumigatus Resistance Mechanism Conferring In Vitro Cross-Resistance to Azole Antifungals Involves a Combination of cyp51A Alterations by MELLADO, E, GARCIA-EFFRON, G, ALCAZAR-FUOLI, L, MELCHERS, W. J. G, VERWEIJ, P. E, CUENCA-ESTRELLA, M, RODRIGUEZ-TUDELA, J. L

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Multiresistance to Nonazole Fungicides in Aspergillus fumigatus TR34/L98H Azole-Resistant Isolates by Gonzalez-Jimenez, I, Garcia-Rubio, R, Monzon, S, Lucio, J, Cuesta, I, Mellado, E

“…Drug resistance is a worldwide problem affecting all pathogens. The human fungal pathogen Aspergillus fumigatus coexists in the environment with other fungi…”
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Candida tropicalis Antifungal Cross-Resistance Is Related to Different Azole Target (Erg11p) Modifications by Forastiero, A, Mesa-Arango, A. C, Alastruey-Izquierdo, A, Alcazar-Fuoli, L, Bernal-Martinez, L, Pelaez, T, Lopez, J. F, Grimalt, J. O, Gomez-Lopez, A, Cuesta, I, Zaragoza, O, Mellado, E

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Rapid development of Candida krusei echinocandin resistance during caspofungin therapy by Forastiero, A, Garcia-Gil, V, Rivero-Menendez, O, Garcia-Rubio, R, Monteiro, M C, Alastruey-Izquierdo, A, Jordan, R, Agorio, I, Mellado, E

“…In invasive candidiasis, there has been an epidemiological shift from Candida albicans to non-albicans species infections, including infections with C…”
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Multiresistance to Nonazole Fungicides in Aspergillus fumigatus TR 34 /L98H Azole-Resistant Isolates by Gonzalez-Jimenez, I, Garcia-Rubio, R, Monzon, S, Lucio, J, Cuesta, I, Mellado, E

“…Drug resistance is a worldwide problem affecting all pathogens. The human fungal pathogen Aspergillus fumigatus coexists in the environment with other fungi…”
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Development and Validation of a High-Resolution Melting Assay To Detect Azole Resistance in Aspergillus fumigatus by Bernal-Martínez, L, Gil, H, Rivero-Menéndez, O, Gago, S, Cuenca-Estrella, M, Mellado, E, Alastruey-Izquierdo, A

“…The global emergence of azole-resistant strains is a growing public health concern. Different patterns of azole resistance are linked to mutations in…”
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The relevance of tumor target expression levels on IgA-mediated cytotoxicity in cancer immunotherapy by Chan, Chilam, Cabanes, Núria Casalé, Jansen, J. H. Marco, Guillaume, Joël, Nederend, Maaike, Passchier, Elsemieke M., Gómez-Mellado, Valentina E., Peipp, Matthias, Boes, Marianne, van Tetering, Geert, Leusen, Jeanette H. W.

“…Recent advances in cancer immunotherapy, particularly the success of immune checkpoint inhibitors, have reignited interest in targeted monoclonal antibodies…”
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The phospholipid flippase ATP8B1 is required for lysosomal fusion in macrophages by Gómez‐Mellado, Valentina E., Ho‐Mok, Kam S., Mark, Vincent A., Wel, Nicole N., Grootemaat, Anita E., Verhoeven, Arthur J., Elferink, Ronald P. J. Oude, Paulusma, Coen C.

“…ATP8B1 is a phospholipid flippase and member of the type 4 subfamily of P‐type ATPases (P4‐ATPase) subfamily. P4‐ATPases catalyze the translocation of…”
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ATP8B1 Deficiency Results in Elevated Mitochondrial Phosphatidylethanolamine Levels and Increased Mitochondrial Oxidative Phosphorylation in Human Hepatoma Cells by Gómez-Mellado, Valentina E., Chang, Jung-Chin, Ho-Mok, Kam S., Bernardino Morcillo, Carmen, Kersten, Remco H. J., Oude Elferink, Ronald P. J., Verhoeven, Arthur J., Paulusma, Coen C.

“…ATP8B1 is a phospholipid flippase that is deficient in patients with progressive familial intrahepatic cholestasis type 1 (PFIC1). PFIC1 patients suffer from…”
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Matrix‐assisted laser desorption ionization time‐of‐flight mass spectrometry for fast and accurate identification of clinically relevant Aspergillus species by Alanio, A., Beretti, J.‐L., Dauphin, B., Mellado, E., Quesne, G., Lacroix, C., Amara, A., Berche, P., Nassif, X., Bougnoux, M.‐E.

“…New Aspergillus species have recently been described with the use of multilocus sequencing in refractory cases of invasive aspergillosis. The classical…”
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TREM1 regulates antifungal immune responses in invasive pulmonary aspergillosis by Bernal-Martínez, L, Gonçalves, SM, de Andres, B, Cunha, C, Gonzalez Jimenez, I, Lagrou, K, Mellado, E, Gaspar, ML, Maertens, JA, Carvalho, A, Alcazar-Fuoli, L

“…Pattern recognition receptors (PRRs) are responsible for Aspergillus fumigatus recognition by innate immunity and its subsequent immune signaling. The…”
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Substitutions at Methionine 220 in the 14α-Sterol Demethylase (Cyp51A) of Aspergillus fumigatus Are Responsible for Resistance In Vitro to Azole Antifungal Drugs by E. Mellado, G. Garcia-Effron, L. Alcazar-Fuoli, M. Cuenca-Estrella, J. L. Rodriguez-Tudela

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A Point Mutation in the 14α-Sterol Demethylase Gene cyp51A Contributes to Itraconazole Resistance in Aspergillus fumigatus by T. M. Diaz-Guerra, E. Mellado, M. Cuenca-Estrella, J. L. Rodriguez-Tudela

“…AUTHOR'S CORRECTION ( vol. 48 , p. 1071 ) Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Diversity of moderately halophilic bacteria producing extracellular hydrolytic enzymes by Sánchez‐Porro, C., Martín, S., Mellado, E., Ventosa, A.

“…Aims: The aim of this study was to determine the diversity of moderately halophilic bacteria with hydrolase activities. Methods and Results: Screening bacteria…”
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In vitro activity of antifungals against Zygomycetes by Alastruey-Izquierdo, A., Castelli, M.V., Cuesta, I., Zaragoza, O., Monzón, A., Mellado, E., Rodríguez-Tudela, J.L.

“…To date, no reference standard for therapy for zygomycosis has been established because there are insufficient clinical data with which to make such a…”
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In vivo efficacy of voriconazole and posaconazole therapy in a novel invertebrate model of Aspergillus fumigatus infection by Forastiero, A, Bernal-Martínez, L, Mellado, E, Cendejas, E, Gomez-Lopez, A

“…Highlights • Galleria mellonella is an alternative model to assess the in vivo efficacy of azoles. • The MICs observed in vitro correlate with the efficacy…”
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Identification of Two Different 14-α Sterol Demethylase-Related Genes (cyp51A and cyp51B) in Aspergillus fumigatus and Other Aspergillus species by MELLADO, E, DIAZ-GUERRA, T. M, CUENCA-ESTRELLA, M, RODRIGUEZ-TUDELA, J. L

“…Author's Correction ( vol. 39 , p. 4225 ) Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Targeted Gene Disruption of the 14-α Sterol Demethylase (cyp51A) in Aspergillus fumigatus and Its Role in Azole Drug Susceptibility by Mellado, E., Garcia-Effron, G., Buitrago, M. J., Alcazar-Fuoli, L., Cuenca-Estrella, M., Rodriguez-Tudela, J. L.

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