Search Results - "Melissa K Frey"
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Universal endometrial cancer tumor typing: How much has immunohistochemistry, microsatellite instability, and MLH1 methylation improved the diagnosis of Lynch syndrome across the population?
Published in Cancer (15-09-2019)“…Background Universal tumor testing for defective DNA mismatch repair (MMR) is recommended for all women diagnosed with endometrial cancer to identify those…”
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Cascading After Peridiagnostic Cancer Genetic Testing: An Alternative to Population-Based Screening
Published in Journal of clinical oncology (01-05-2020)“…Despite advances in DNA sequencing technology and expanded medical guidelines, the vast majority of individuals carrying pathogenic variants of common cancer…”
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Financial toxicity, mental health, and gynecologic cancer treatment: The effect of the COVID‐19 pandemic among low‐income women in New York City
Published in Cancer (15-07-2021)“…BACKGROUND New York City (NYC) emerged as an epicenter of the COVID‐19 pandemic, and marginalized populations were affected at disproportionate rates. The…”
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Prevalence of nonfounder BRCA1/2 mutations in Ashkenazi Jewish patients presenting for genetic testing at a hereditary breast and ovarian cancer center
Published in Cancer (01-03-2019)“…Background Genetic assessment in Ashkenazi Jewish (AJ) patients often is limited to BRCA1/2 founder mutation testing. With access to time‐efficient and…”
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Protocol for Health Risk Information Technology-Assisted Genetic Evaluation (HeRITAGE): a randomised controlled trial of digital genetic cancer risk assessment in a diverse underserved gynaecology clinic
Published in BMJ open (05-09-2024)“…IntroductionIn the USA, up to 95% of individuals harbouring cancer-predisposing germline pathogenic variants have not been identified despite recommendations…”
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Ovarian cancer survivors' acceptance of treatment side effects evolves as goals of care change over the cancer continuum
Published in Gynecologic oncology (01-08-2017)“…Abstract Objectives Women with ovarian cancer can have long overall survival and goals of treatment change over time from cure to remission to stable disease…”
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Risk-Reducing Bilateral Salpingo-Oophorectomy for Ovarian Cancer: A Review and Clinical Guide for Hereditary Predisposition Genes
Published in JCO oncology practice (01-03-2022)“…Pathogenic germline variants underlie up to 20% of ovarian cancer (OC) and are associated with varying degrees of risk for OC. For mutations in high-penetrance…”
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Evaluation of lysophosphatidic acid in vaginal fluid as a biomarker for ovarian cancer: A pilot study
Published in European journal of obstetrics & gynecology and reproductive biology: X (01-04-2019)“…There remains a need to differentiate between women with a benign or a malignant adnexal mass prior to surgery. As part of an ongoing evaluation of vaginal…”
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Impact of postoperative intensity-modulated radiation therapy (IMRT) on the rate of bowel obstruction in gynecologic malignancy
Published in Gynecologic oncology (01-10-2016)“…Abstract Objective The purpose was to determine the potential impact of IMRT on the rate of bowel obstruction (BO), in patients with gynecologic malignancies…”
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Could fertility-sparing surgery be considered for women with early stage ovarian clear cell carcinoma?
Published in Journal of gynecologic oncology (01-11-2017)“…The aim of the present retrospective population-based study was to investigate the oncologic impact of uterine and ovarian preservation (OP) in premenopausal…”
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Do people with hereditary cancer syndromes inform their at-risk relatives? A systematic review and meta-analysis
Published in PEC innovation (01-12-2023)“…To evaluate rates of familial disclosure of hereditary cancer syndrome information. A systematic review and meta-analysis was conducted in accordance with…”
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Attitudes and beliefs regarding complementary and alternative medicine in a diverse gynecologic oncology patient population
Published in Gynecologic oncology reports (01-08-2023)“…•Complementary and alternative medicine use among diverse gynecologic oncology patients is less common than expected.•Race and ethnicity influence perceived…”
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The influence of BRCA variants of unknown significance on cancer risk management decision-making
Published in Journal of gynecologic oncology (01-07-2019)“…To compare gynecological cancer risk management between women with BRCA variants of unknown significance (VUS) to women with negative genetic testing…”
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Metastatic epithelial ovarian cancer to Meckel’s cave with leptomeningeal spread at time of diagnosis
Published in Gynecologic oncology reports (01-11-2020)“…•Rare case of aggressive epithelial ovarian cancer with brain metastasis at time of initial diagnosis.•First reported case of epithelial ovarian cancer with…”
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Enhanced recovery Pathways in gynecologic surgery: Are they safe and effective in the elderly?
Published in Gynecologic oncology reports (01-11-2021)“…•Data on the safety of ERP in elderly patients undergoing complex gynecologic surgery is sparse.•Elderly patients undergoing gynecologic laparotomy achieved…”
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Room for improvement in capturing cancer family history in a gynecologic oncology outpatient setting
Published in Gynecologic oncology reports (01-04-2022)“…•Collection of family health history is necessary for identifying patients at risk for hereditary cancer.•Patients with either a relative with cancer or prior…”
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Role of adjuvant chemotherapy in the management of non-granulosa cell ovarian sex cord-stromal tumors
Published in Journal of gynecologic oncology (01-03-2019)“…To investigate the role of adjuvant chemotherapy (CT) in the management of ovarian non-granulosa cell (GC) sex cord-stromal tumors (SCSTs). The National Cancer…”
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Does the presence of adenomyosis and lymphovascular space invasion affect lymph node status in patients with endometrioid adenocarcinoma of the endometrium?
Published in American journal of obstetrics and gynecology (01-11-2012)“…Objective We sought to determine the prevalence of adenomyosis and assess its effect on lymph node status in endometrioid adenocarcinoma of the endometrium…”
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Treatment patterns and outcomes among women with brain metastases from gynecologic malignancies
Published in Gynecologic oncology reports (01-11-2020)“…•Longer time between initial cancer diagnosis and brain metastasis is associated with improved survival.•Brain metastasis treated with surgery and radiation is…”
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