Search Results - "Melin, Celine"

Mechanical stress rapidly induces E-resveratrol and E-piceatannol biosynthesis in grape canes stored as a freshly-pruned byproduct by Billet, Kévin, Houillé, Benjamin, Besseau, Sébastien, Mélin, Céline, Oudin, Audrey, Papon, Nicolas, Courdavault, Vincent, Clastre, Marc, Giglioli-Guivarc'h, Nathalie, Lanoue, Arnaud

“…•A method to induce stilbenoids in freshly-pruned grape canes is described.•A mechanical stress is applied by cutting the canes in short length…”
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Yeast Platforms for Production and Screening of Bioactive Derivatives of Rauwolscine by Bradley, Samuel A., Hansson, Frederik G., Lehka, Beata J., Rago, Daniela, Pinho, Pedro, Peng, Huadong, Adhikari, Khem B., Haidar, Ahmad K., Hansen, Lea G., Volkova, Daria, Holtz, Maxence, Muyo Abad, Sergi, Ma, Xin, Koudounas, Konstantinos, Besseau, Sébastien, Gautron, Nicolas, Mélin, Céline, Marc, Jillian, Birer Williams, Caroline, Courdavault, Vincent, Jensen, Emil D., Keasling, Jay D., Zhang, Jie, Jensen, Michael K.

“…Monoterpene indole alkaloids (MIAs) make up a highly bioactive class of metabolites produced by a range of tropical and subtropical plants. The corynanthe-type…”
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CHASE-Containing Histidine Kinase Receptors in Apple Tree: From a Common Receptor Structure to Divergent Cytokinin Binding Properties and Specific Functions by Daudu, Dimitri, Allion, Elsa, Liesecke, Franziska, Papon, Nicolas, Courdavault, Vincent, Dugé de Bernonville, Thomas, Mélin, Céline, Oudin, Audrey, Clastre, Marc, Lanoue, Arnaud, Courtois, Martine, Pichon, Olivier, Giron, David, Carpin, Sabine, Giglioli-Guivarc'h, Nathalie, Crèche, Joël, Besseau, Sébastien, Glévarec, Gaëlle

“…Cytokinin signaling is a key regulatory pathway of many aspects in plant development and environmental stresses. Herein, we initiated the identification and…”
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Design, synthesis and evaluation of new marine alkaloid-derived pentacyclic structures with anti-tumoral potency by Boucle, Sebastien, Melin, Celine, Clastre, Marc, Guillard, Jerome

“…This work describes the synthesis and biological evaluation of a new heterocyclic hybrid derived from the ellipticine and the marine alkaloid makaluvamine A…”
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An additional Meyerozyma guilliermondii IMH3 gene confers mycophenolic acid resistance in fungal CTG clade species by Defosse, Tatiana A., Mélin, Céline, Clastre, Marc, Besseau, Sébastien, Lanoue, Arnaud, Glévarec, Gaëlle, Oudin, Audrey, Dugé de Bernonville, Thomas, Vandeputte, Patrick, Linder, Tomas, Bouchara, Jean-Philippe, Courdavault, Vincent, Giglioli-Guivarc'h, Nathalie, Papon, Nicolas

“…The fungal CTG clade comprises a number of well-known yeasts that impact human health or with high biotechnological potential. To further extend the set of…”
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Disrupting the methionine biosynthetic pathway in Candida guilliermondii: characterization of the MET2 gene as counter‐selectable marker by Obando Montoya, Erika J, Mélin, Céline, Blanc, Nathalie, Lanoue, Arnaud, Foureau, Emilien, Boudesocque, Leslie, Prie, Gildas, Simkin, Andrew J, Crèche, Joël, Atehortùa, Lucia, Giglioli‐Guivarc'h, Nathalie, Clastre, Marc, Courdavault, Vincent, Papon, Nicolas

“…Candida guilliermondii (teleomorph Meyerozyma guilliermondii) is an ascomycetous species belonging to the fungal CTG clade. This yeast remains actively studied…”
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Setting-up a fast and reliable cytokinin biosensor based on a plant histidine kinase receptor expressed in Saccharomyces cerevisiae by Daudu, Dimitri, Kisiala, Anna, Werner Ribeiro, Carolina, Mélin, Céline, Perrot, Laura, Clastre, Marc, Courdavault, Vincent, Papon, Nicolas, Oudin, Audrey, Courtois, Martine, Dugé de Bernonville, Thomas, Gaucher, Matthieu, Degrave, Alexandre, Lanoue, Arnaud, Lanotte, Philippe, Schouler, Catherine, Brisset, Marie-Noëlle, Emery, R.J. Neil, Pichon, Olivier, Carpin, Sabine, Giglioli-Guivarc’h, Nathalie, Crèche, Joël, Besseau, Sébastien, Glévarec, Gaëlle

“…•The cytokinin biosensor is based on a yeast sln1Δ mutant complemented by a plant HK.•Biosensing assay was developed to detect cytokinins from bacterial…”
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Two Tabersonine 6,7-Epoxidases Initiate Lochnericine-Derived Alkaloid Biosynthesis in Catharanthus roseus by Carqueijeiro, Inês, Brown, Stephanie, Chung, Khoa, Dang, Thu-Thuy, Walia, Manish, Besseau, Sébastien, de Bernonville, Thomas Dugé, Oudin, Audrey, Lanoue, Arnaud, Billet, Kevin, Munsch, Thibaut, Koudounas, Konstantinos, Melin, Céline, Godon, Charlotte, Razafimandimby, Bienvenue, de Craene, Johan-Owen, Glévarec, Gaëlle, Marc, Jillian, Giglioli-Guivarc'h, Nathalie, Clastre, Marc, St-Pierre, Benoit, Papon, Nicolas, Andrade, Rodrigo B., O'Connor, Sarah E., Courdavault, Vincent

“…Lochnericine is a major monoterpene indole alkaloid (MIA) in the roots of Madagascar periwinkle (Catharanthus roseus). Lochnericine is derived from the…”
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Different processing of meningeal and cutaneous pain information in the spinal trigeminal nucleus caudalis by Melin, Céline, Jacquot, Florian, Vitello, Nicolas, Dallel, Radhouane, Artola, Alain

“…Introduction Within superficial trigeminal nucleus caudalis (Sp5C) (laminae I/II), meningeal primary afferents project exclusively to lamina I, whereas…”
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Segmental disinhibition suppresses C-fiber inputs to the rat superficial medullary dorsal horn via the activation of GABAB receptors by Melin, Céline, Jacquot, Florian, Dallel, Radhouane, Artola, Alain

“…Specialized primary afferents, although they terminate in different laminae within the dorsal horn (DH), are known to interact through local circuit excitatory…”
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Tonic and phasic descending dopaminergic controls of nociceptive transmission in the medullary dorsal horn by Lapirot, Olivier, Melin, Céline, Modolo, Alice, Nicolas, Charline, Messaoudi, Yassine, Monconduit, Lénaic, Artola, Alain, Luccarini, Philippe, Dallel, Radhouane

“…The transfer of nociceptive information at the level of dorsal horn is subject to extensive processing by both local segmental and supraspinal mechanisms,…”
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Enhanced bioproduction of anticancer precursor vindoline by yeast cell factories by Kulagina, Natalja, Guirimand, Grégory, Melin, Céline, Lemos‐Cruz, Pamela, Carqueijeiro, Ines, De Craene, Johan‐Owen, Oudin, Audrey, Heredia, Vladimir, Koudounas, Konstantinos, Unlubayir, Marianne, Lanoue, Arnaud, Imbault, Nadine, St‐Pierre, Benoit, Papon, Nicolas, Clastre, Marc, Giglioli‐Guivarc’h, Nathalie, Marc, Jillian, Besseau, Sébastien, Courdavault, Vincent

“…Summary The pharmaceutical industry faces a growing demand and recurrent shortages in many anticancer plant drugs given their extensive use in human…”
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A single gene encodes isopentenyl diphosphate isomerase isoforms targeted to plastids, mitochondria and peroxisomes in Catharanthus roseus by Guirimand, Grégory, Guihur, Anthony, Phillips, Michael A., Oudin, Audrey, Glévarec, Gaëlle, Melin, Céline, Papon, Nicolas, Clastre, Marc, St-Pierre, Benoit, Rodríguez-Concepción, Manuel, Burlat, Vincent, Courdavault, Vincent

“…Isopentenyl diphosphate isomerases (IDI) catalyze the interconversion of the two isoprenoid universal C5 units, isopentenyl diphosphate and dimethylally…”
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Organization of projections from the spinal trigeminal subnucleus oralis to the spinal cord in the rat: A neuroanatomical substrate for reciprocal orofacial–cervical interactions by Devoize, Laurent, Doméjean, Sophie, Melin, Céline, Raboisson, Patrick, Artola, Alain, Dallel, Radhouane

“…Abstract The organization of efferent projections from the spinal trigeminal nucleus oralis (Sp5O) to the spinal cord in the rat was studied using the…”
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Molecular cloning and functional characterization of Catharanthus roseus hydroxymethylbutenyl 4-diphosphate synthase gene promoter from the methyl erythritol phosphate pathway by Ginis, Olivia, Courdavault, Vincent, Melin, Céline, Lanoue, Arnaud, Giglioli-Guivarc’h, Nathalie, St-Pierre, Benoit, Courtois, Martine, Oudin, Audrey

“…The Madagascar periwinkle produces monoterpenoid indole alkaloids (MIA) of high interest due to their therapeutical values. The terpenoid moiety of MIA is…”
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A new series of vectors for constitutive, inducible or repressible gene expression in Candida guilliermondii by Defosse, Tatiana A., Melin, Céline, Obando Montoya, Erika J., Lanoue, Arnaud, Foureau, Emilien, Glévarec, Gaëlle, Oudin, Audrey, Simkin, Andrew J., Crèche, Joël, Atehortùa, Lucia, Giglioli-Guivarc’h, Nathalie, Clastre, Marc, Courdavault, Vincent, Papon, Nicolas

“…•The biotechnological potential of C. guilliermondii is now well established.•The number of expression systems in C. guilliermondii remains limited.•We…”
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Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast by Bradley, Samuel A., Lehka, Beata J., Hansson, Frederik G., Adhikari, Khem B., Rago, Daniela, Rubaszka, Paulina, Haidar, Ahmad K., Chen, Ling, Hansen, Lea G., Gudich, Olga, Giannakou, Konstantina, Lengger, Bettina, Gill, Ryan T., Nakamura, Yoko, de Bernonville, Thomas Dugé, Koudounas, Konstantinos, Romero-Suarez, David, Ding, Ling, Qiao, Yijun, Frimurer, Thomas M., Petersen, Anja A., Besseau, Sébastien, Kumar, Sandeep, Gautron, Nicolas, Melin, Celine, Marc, Jillian, Jeanneau, Remi, O’Connor, Sarah E., Courdavault, Vincent, Keasling, Jay D., Zhang, Jie, Jensen, Michael K.

“…Monoterpenoid indole alkaloids (MIAs) represent a large class of plant natural products with marketed pharmaceutical activities against a wide range of…”
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Triple subcellular targeting of isopentenyl diphosphate isomerases encoded by a single gene by Guirimand, Grégory, Guihur, Anthony, Phillips, Michael A., Oudin, Audrey, Glévarec, Gaëlle, Mahroug, Samira, Melin, Céline, Papon, Nicolas, Clastre, Marc, Giglioli-Guivarc'h, Nathalie, St-Pierre, Benoit, Rodríguez-Concepción, Manuel, Burlat, Vincent, Courdavault, Vincent

“…Isopentenyl diphosphate isomerase (IDI) is a key enzyme of the isoprenoid pathway, catalyzing the interconversion of isopentenyl diphosphate and dimethylallyl…”
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TRP5/5-fluoroanthranilic acid counter-selection system for gene disruption in Candida guilliermondii by Foureau, Emilien, Clastre, Marc, Millerioux, Yoann, Simkin, Andrew J, Cornet, Lucie, Dutilleul, Christelle, Besseau, Sébastien, Marais, Emeline, Melin, Céline, Guillard, Jérôme, Crèche, Joël, Giglioli-Guivarc’h, Nathalie, Courdavault, Vincent, Papon, Nicolas

“…Candida guilliermondii is an interesting biotechnological model for the industrial production of value-added metabolites and also remains an opportunistic…”
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Segmental disinhibition suppresses C‐fiber inputs to the rat superficial medullary dorsal horn via the activation of GABA B receptors by Melin, Céline, Jacquot, Florian, Dallel, Radhouane, Artola, Alain

“…Abstract Specialized primary afferents, although they terminate in different laminae within the dorsal horn ( DH ), are known to interact through local circuit…”
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