Effect of Low-Intensity 900 MHz Frequency Electromagnetic Radiation on Rat Brain Enzyme Activities Linked to Energy Metabolism

The research deals with the effect of low-intensity 900 MHz frequency electromagnetic radiation (EMR), power density 25 μW/cm2, on the following rat brain and blood serum enzyme activities: creatine kinase (CK), playing a central role in the process of storing and distributing the cell energy, as we...

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Bibliographic Details
Published in:	Radiat͡s︡ionnai͡a︡ biologii͡a︡, radioėkologii͡a Vol. 55; no. 6; p. 625
Main Authors:	Petrosyan, M S, Nersesova, L S, Gazaryants, M G, Meliksetyan, G O, Malakyan, M G, Bajinyan, S A, Akopian, J I
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-11-2015
Subjects:	Adaptation, Physiological Alanine Transaminase - blood Alanine Transaminase - metabolism Animals Aspartate Aminotransferases - blood Aspartate Aminotransferases - metabolism Brain - enzymology Brain - metabolism Brain - radiation effects Creatine Kinase - blood Creatine Kinase - metabolism Dose-Response Relationship, Radiation Electromagnetic Radiation Energy Metabolism - radiation effects Male Rats Whole-Body Irradiation
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Summary:	The research deals with the effect of low-intensity 900 MHz frequency electromagnetic radiation (EMR), power density 25 μW/cm2, on the following rat brain and blood serum enzyme activities: creatine kinase (CK), playing a central role in the process of storing and distributing the cell energy, as well as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) that play a key role in providing the conjunction of carbohydrate and amino acid metabolism. The comparative analysis of the changes in the enzyme activity studied at different times following the two-hour single, as well as fractional, radiation equivalent of the total time showed that the most radiosensitive enzyme is the brain creatine kinase, which may then be recommended as a marker of the radio frequency radiation impact. According to the analysis of the changing dynamics of the CK, ALT and AST activity level, with time these changes acquire the adaptive character and are directed to compensate the damaged cell energy metabolism.
ISSN:	0869-8031
DOI:	10.7868/s0869803115060119