Search Results - "Melikian, Anita"

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development by Burns, Jennifer M, Summers, Bretton C, Wang, Yu, Melikian, Anita, Berahovich, Rob, Miao, Zhenhua, Penfold, Mark E T, Sunshine, Mary Jean, Littman, Dan R, Kuo, Calvin J, Wei, Kevin, McMaster, Brian E, Wright, Kim, Howard, Maureen C, Schall, Thomas J

“…The chemokine stromal cell-derived factor (SDF-1; also known as chemokine ligand 12 [CXCL12]) regulates many essential biological processes, including cardiac…”
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Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of .gamma.-aminobutyric acid acting as selective GABA-A antagonists by Wermuth, Camille Georges, Bourguignon, Jean Jacques, Schlewer, Gilbert, Gies, Jean Pierre, Schoenfelder, Angele, Melikian, Anita, Bouchet, Marie Jeanne, Chantreux, Dominique, Molimard, Jean Charles

“…We have recently shown that an arylaminopyridazine derivative of GABA, SR 95103 [2-(3-carboxypropyl)-3-amino-4-methyl-6-phenylpyridazinium chloride], is a…”
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Condensation of muscimol or thiomuscimol with aminopyridazines yields GABA-A antagonists by Melikian, Anita, Schlewer, Gilbert, Chambon, Jean Pierre, Wermuth, Camille Georges

“…Ten analogs of muscimol and thiomuscimol in which the amino function was delocalized in an amidinic system were prepared by N2 alkylation of…”
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(S)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno- 1H,13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-dione (LY333531) and Related Analogues:  Isozyme Selective Inhibitors of Protein Kinase Cβ by Jirousek, Michael R, Gillig, James R, Gonzalez, Cecile M, Heath, William F, McDonald, John H, Neel, David A, Rito, Christopher J, Singh, Upinder, Stramm, Lawrence E, Melikian-Badalian, Anita, Baevsky, Matthew, Ballas, Lawrence M, Hall, Steven E, Winneroski, Leonard L, Faul, Margaret M

“…Protein kinase C (PKC) is a family of closely related serine and threonine kinases. Overactivation of some PKC isozymes has been postulated to occur in several…”
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Solid-phase synthesis of substituted quinoline and isoquinoline derivatives using heterocyclic N-oxide chemistry by Hoemann, Michael Z., Melikian-Badalian, Anita, Kumaravel, G., Hauske, James R.

“…Using heterocyclic- N-oxide chemistry, various substituted quinoline and isoquinoline compounds were synthesized on the solid support in excellent purity and…”
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Synthesis of bisindolylmaleimide macrocycles by Jirousek, Michael R, Gillig, James R, Neel, David A, Rito, Christopher J, O'Bannon, Douglas, Heath, William F, McDonald, John H, Faul, Margaret M, Winneroski, Leonard L, Melikian-Badalian, Anita, Baevsky, Matthew, Ballas, Larwence M, Hall, Steven E

“…The synthesis of a novel class of N-N′-macrocyclic bisindolylmaleimides is reported. The key step involves a remarkably efficient intramolecular cyclization…”
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( S )-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno- 1 H ,13 H -dibenzo[ e , k ]pyrrolo[3,4- h ][1,4,13]oxadiazacyclohexadecene-1,3(2 H )-dione (LY333531) and Related Analogues:  Isozyme Selective Inhibitors of Protein Kinase Cβ by Jirousek, Michael R., Gillig, James R., Gonzalez, Cecile M., Heath, William F., McDonald, John H., Neel, David A., Rito, Christopher J., Singh, Upinder, Stramm, Lawrence E., Melikian-Badalian, Anita, Baevsky, Matthew, Ballas, Lawrence M., Hall, Steven E., Winneroski, Leonard L., Faul, Margaret M.

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