Search Results - "Melikhova, M E"

A statistical model and computer program to estimate association constants for the binding of fluorescent-labelled monoclonal antibodies to cell surface antigens and to interpret shifts in flow cytometry data resulting from alterations in gene expression by Bardsley, W G, Wilson, A R, Kyprianou, E K, Melikhova, E M

“…Flow cytometry is used to obtain estimates for the distribution of fluorescent ligands bound to cell surface receptors throughout a cell sample. The equipment…”
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Receptor binding on whole cells can oscillate by Sukhomlin, T K, Melikhova, E M, Kurochkin, I N, Varfolomeev, S D

“…The study of the kinetics of binding of the opiate receptor agonist [3H]DADLE with NG108-15 cell suspensions has revealed a new periodic biological phenomenon,…”
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Analysis of ligand-receptor binding by the difference method by Melikhova, E M, Kurochkin, I N, Zaitsev, S V, Varfolomeev, S D

“…A new method has been proposed for analysis of experimental data on ligand-receptor binding at equilibrium. This method makes it possible to detect…”
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Cardiotropic activity of synthetic peptide CH3CO-Lys-Lys-Arg-Arg-NH2 (protectin) by Sazhin, A I, Zaĭtseva, M A, Melikhova, M E, Ezhov, N F, Sadovnikov, V B, Navolotskaia, E V

“…Peptide CH3CO-Lys-Lys-Arg-Arg-NH2 (protectin) was synthesized and its activity was studied on the model of experimental myocardial infarction in rats in…”
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Optimal design: A computer program to study the best possible spacing of design points for model discrimination by Bardsley, W.G., Wood, R.M.W., Melikhova, E.M.

“…Optimal design is largely concerned with selecting design points so as to maximise the precision of parameter estimates once the correct model has been…”
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Theoretical examination of kinetic regularities in interaction of second messenger systems upon activation of cells by an external chemical signal by Melikhova, E M, Kurochkin, I N

“…A model of cell activation under the action of an external chemical signal is examined. The model is based on the assumption of simultaneous stimulation of, as…”
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Receptor binding oscillations by Sukhomlin, T K, Melikhova, E M, Kurochkin, I N, Varfolomeev, S D

“…A kinetic analysis of the delta-opiate receptor agonist, [3H] DADLE, binding to cell (NG108-15) suspensions has led to the discovery of a new periodic…”
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