Search Results - "Melikhova, Ekaterina Y"

Directing Group Enhanced Carbonylative Ring Expansions of Amino-Substituted Cyclopropanes: Rhodium-Catalyzed Multicomponent Synthesis of N‑Heterobicyclic Enones by Shaw, Megan H, Melikhova, Ekaterina Y, Kloer, Daniel P, Whittingham, William G, Bower, John F

“…Aminocyclopropanes equipped with suitable N-directing groups undergo efficient and regioselective Rh-catalyzed carbonylative C–C bond activation. Trapping of…”
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Dehydromicrosclerodermin B and Microsclerodermin J: Total Synthesis and Structural Revision by Melikhova, Ekaterina Y., Pullin, Robert D. C., Winter, Christian, Donohoe, Timothy J.

“…The total synthesis of dehydromicrosclerodermin B and microsclerodermin J is described. Efficient approaches to the unusual amino acids in the target molecules…”
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Tethered Aminohydroxylation: Synthesis of the β‑Amino Acid of Microsclerodermins A and B by Pullin, Robert D. C, Rathi, Akshat H, Melikhova, Ekaterina Y, Winter, Christian, Thompson, Amber L, Donohoe, Timothy J

“…The utility of the tethered aminohydroxylation (TA) has been demonstrated by synthesis of the complex β-amino acid residue of microsclerodermins A and B. The…”
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Application of Experimental Design (DoE) to Improve a Very Dilute Workup Procedure by Melikhova, Ekaterina Y., Smith, Dan A., Moseley, Jonathan D.

“…A three-level face-centered central composite experimental design was applied to the reaction parameters (concentration, stoichiometry, temperature) of an…”
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Early Process Development and Scale-Up of Orally Active Apomorphine Drug Candidates by Melikhova, Ekaterina Y., Derrien, Nolwenn, Fleary-Roberts, Nadia, Forsyth, Siân M., Papadouli, Sofia, Ruda, Antonio M., Thangavadivale, Vargini G., Tyler, Simon N. G., Moseley, Jonathan D.

“…The manufacturing route to a novel apomorphine Parkinson’s drug candidate (MCL-509) has been developed from a mg laboratory scale to that suitable for use on a…”
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DehydromicroscleroderminB and MicroscleroderminJ: Total Synthesis and Structural Revision by Melikhova, Ekaterina Y, Pullin, Robert D C, Winter, Christian, Donohoe, Timothy J

“…The total synthesis of dehydromicroscleroderminB and microscleroderminJ is described. Efficient approaches to the unusual amino acids in the target molecules…”
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Dehydromicrosclerodermin B and Microsclerodermin J: Total Synthesis and Structural Revision by Melikhova, Ekaterina Y., Pullin, Robert D. C., Winter, Christian, Donohoe, Timothy J.

“…The total synthesis of dehydromicrosclerodermin B and microsclerodermin J is described. Efficient approaches to the unusual amino acids in the target molecules…”
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DehydromicroscleroderminB and MicroscleroderminJ: Total Synthesis and Structural Revision by Melikhova, Ekaterina Y, Pullin, Robert D C, Winter, Christian, Donohoe, Timothy J

“…The total synthesis of dehydromicroscleroderminB and microscleroderminJ is described. Efficient approaches to the unusual amino acids in the target molecules…”
Get full text