Search Results - "Melie‐Garcia, Lester"
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1
Evolution of white matter tract microstructure across the life span
Published in Human brain mapping (01-05-2019)“…The human brain undergoes dramatic structural change over the life span. In a large imaging cohort of 801 individuals aged 7–84 years, we applied quantitative…”
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2
Ragu: A Free Tool for the Analysis of EEG and MEG Event-Related Scalp Field Data Using Global Randomization Statistics
Published in Computational Intelligence and Neuroscience (01-01-2011)“…We present a program (Ragu; Randomization Graphical User interface) for statistical analyses of multichannel event-related EEG and MEG experiments. Based on…”
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3
Method to Determine the Presence of Averaged Event-Related Fields Using Randomization Tests
Published in Brain topography (01-09-2010)“…We present a simple and effective method to test whether an event consistently activates a set of brain electric sources across repeated measurements of…”
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4
Networks of myelin covariance
Published in Human brain mapping (01-04-2018)“…Networks of anatomical covariance have been widely used to study connectivity patterns in both normal and pathological brains based on the concurrent changes…”
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5
Apolipoprotein E4 effects on topological brain network organization in mild cognitive impairment
Published in Scientific reports (12-01-2021)“…The Apolipoprotein E isoform E4 (ApoE4) is consistently associated with an elevated risk of developing late-onset Alzheimer’s Disease (AD); however, less is…”
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A Multicenter Longitudinal MRI Study Assessing LeMan‐PV Software Accuracy in the Detection of White Matter Lesions in Multiple Sclerosis Patients
Published in Journal of magnetic resonance imaging (01-09-2023)“…Background Detecting new and enlarged lesions in multiple sclerosis (MS) patients is needed to determine their disease activity. LeMan‐PV is a software…”
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7
Spherical Deconvolution of Multichannel Diffusion MRI Data with Non-Gaussian Noise Models and Spatial Regularization
Published in PloS one (15-10-2015)“…Spherical deconvolution (SD) methods are widely used to estimate the intra-voxel white-matter fiber orientations from diffusion MRI data. However, while some…”
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8
Remodeling of brain morphology in temporal lobe epilepsy
Published in Brain and behavior (01-11-2020)“…Background Mesial temporal lobe epilepsy (TLE) is one of the most widespread neurological network disorders. Computational anatomy MRI studies demonstrate a…”
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Neurobiological origin of spurious brain morphological changes: A quantitative MRI study
Published in Human brain mapping (01-05-2016)“…The high gray‐white matter contrast and spatial resolution provided by T1‐weighted magnetic resonance imaging (MRI) has made it a widely used imaging protocol…”
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10
Glucose metabolism during resting state reveals abnormal brain networks organization in the Alzheimer's disease and mild cognitive impairment
Published in PloS one (23-07-2013)“…This paper aims to study the abnormal patterns of brain glucose metabolism co-variations in Alzheimer disease (AD) and Mild Cognitive Impairment (MCI) patients…”
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11
Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study
Published in Nature communications (09-11-2022)“…Growing evidence links COVID-19 with acute and long-term neurological dysfunction. However, the pathophysiological mechanisms resulting in central nervous…”
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12
Advanced MRI Measures of Myelin and Axon Volume Identify Repair in Multiple Sclerosis
Published in Annals of neurology (10-10-2024)“…Pathological studies suggest that multiple sclerosis (MS) lesions endure multiple waves of damage and repair; however, the dynamics and characteristics of…”
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13
Mapping grip force to motor networks
Published in NeuroImage (Orlando, Fla.) (01-04-2021)“…There is ongoing debate about the role of cortical and subcortical brain areas in force modulation. In a whole-brain approach, we sought to investigate the…”
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14
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis
Published in Brain pathology (Zurich, Switzerland) (01-11-2023)“…Quantitative MRI (qMRI) probes the microstructural properties of the central nervous system (CNS) by providing biophysical measures of tissue characteristics…”
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15
Studying the topological organization of the cerebral blood flow fluctuations in resting state
Published in NeuroImage (Orlando, Fla.) (01-01-2013)“…In this paper the cerebral blood flow (CBF) in resting state obtained from SPECT imaging is employed as a hemodynamics descriptor to study the concurrent…”
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16
Anterior horn atrophy in the cervical spinal cord: A new biomarker in progressive multiple sclerosis
Published in Multiple sclerosis (01-05-2023)“…Background: Spinal cord (SC) gray and white matter pathology plays a central role in multiple sclerosis (MS). Objective: We aimed to investigate the extent,…”
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Studying the human brain anatomical network via diffusion-weighted MRI and Graph Theory
Published in NeuroImage (Orlando, Fla.) (15-04-2008)“…Our goal is to study the human brain anatomical network. For this, the anatomical connection probabilities (ACP) between 90 cortical and subcortical brain gray…”
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18
Dopaminergic modulation of motor network compensatory mechanisms in Parkinson's disease
Published in Human brain mapping (15-10-2019)“…The dopaminergic system has a unique gating function in the initiation and execution of movements. When the interhemispheric imbalance of dopamine inherent to…”
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19
Brain hemispheric structural efficiency and interconnectivity rightward asymmetry in human and nonhuman primates
Published in Cerebral cortex (New York, N.Y. 1991) (01-01-2011)“…Evidence for interregional structural asymmetries has been previously reported for brain anatomic regions supporting well-described functional lateralization…”
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20
A novel imaging marker of cortical “cellularity” in multiple sclerosis patients
Published in Scientific reports (29-04-2024)“…Pathological data showed focal inflammation and regions of diffuse neuronal loss in the cortex of people with multiple sclerosis (MS). In this work, we applied…”
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