Search Results - "Melia, Ciara"
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Increased uptake of the P2X7 receptor radiotracer 18F‐JNJ‐64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice
Published in Epilepsia (Copenhagen) (01-02-2023)“…Objective The P2X7 receptor (P2X7R) is an important contributor to neuroinflammation, responding to extracellularly released adenosine triphosphate. Expression…”
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Journal Article -
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Increased uptake of the P2X7 receptor radiotracer 18 F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice
Published in Epilepsia (Copenhagen) (01-02-2023)“…The P2X7 receptor (P2X7R) is an important contributor to neuroinflammation, responding to extracellularly released adenosine triphosphate. Expression of the…”
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Journal Article -
3
Opposing effects of the purinergic P2X7 receptor on seizures in neurons and microglia in male mice
Published in Brain, behavior, and immunity (01-08-2024)“…•P2X7R signaling regulates both glial and neuronal genes during seizures.•P2X7R deficiency in microglia reduces seizure severity and leads to an…”
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Journal Article